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ORASURE TECHNOLOGIES INC Capital/Financing Update 2022

May 18, 2022

33573_rns_2022-05-18_f56b1413-c429-4b97-b1a5-8f98ed6ada26.zip

Capital/Financing Update

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CORRESP 1 filename1.htm CORRESP

OraSure Technologies, Inc.

220 East First Street

Bethlehem, Pennsylvania 18015

May 18, 2022

VIA EDGAR

United States Securities and Exchange Commission

Division of Corporation Finance

Office of Life Sciences

100 F Street NE

Washington, D.C. 20549

Attn: Michael Davis and Celeste Murphy

Re: OraSure Technologies, Inc.

Registration Statement on Form S-3

Filed February 10, 2022 (File No. 333-262633)

Ladies and Gentlemen:

Pursuant to Rule 461 under the Securities Act of 1933, as amended, OraSure Technologies, Inc. (the “ Company ”) hereby requests that the effective date of the Company’s Registration Statement on Form S-3 (File No. 333-262633) (the “ Registration Statement ”) be accelerated so that the Company’s Registration Statement will become effective at 4:00 PM, Eastern Time, on May 20, 2022, or as soon thereafter as is practicable.

Please contact Jennifer Porter of Troutman Pepper Hamilton Sanders LLP, counsel to the Company, at (215) 981-4339 to provide notice of effectiveness or if you have any questions or comments concerning this request.

Very truly yours,
ORASURE TECHNOLOGIES, INC.
By: /s/ Agnieszka Gallagher
Name: Agnieszka Gallagher
Title: Senior Vice President, General Counsel and Secretary