Opthea Ltd — Regulatory Filings 2006

Oct 26, 2006

27 October 2006

The Companies Section The Australian Stock Exchange Limited 530 Collins Street MELBOURNE VIC 3000

No. of Pages: 1

Dear Sir/Madam

Results of Annual General Meeting: 27 October 2006

As required by section 251AA(2) of the Corporations Act and ASX Listing Rule 3.13.2, Circadian Technologies Limited advises that the resolutions set out in its Notice of Annual General Meeting, which was lodged with the ASX on 22 September 2006, were put to that meeting today and were carried on a show of hands.

Validly appointed proxies totalling 14,731,620 shares were received, representing 36.71% of the total issued shares in the Company. The proxies were to be exercised as follows for each respective resolution:

	In favour	Against	Abstention	Proxy's discretion
ORDINARY BUSINESS
Resolution $1 -$ Adoption of the Remuneration Report:
No. of shares represented by proxies	13,830,301	177,452	126.715	597,152
Resolution 2 – Re-election of Dr John Stocker as a director:
No. of shares represented by proxies	14.083.185	31,831	12,185	604.419
Resolution 3 – Re-election of Mr Graeme Kaufman as a director:
No. of shares represented by proxies	14,064,116	47,400	14.185	605.919

Yours faithfully

Natalie Korchev Company Secretary

Level 1, 10 Wallace Avenue, Toorak, Victoria 3442, Australia 2. +61 (0) 5922-0292 Circadian Technologies Limited F +61(3) 9824 0083 ABN 32 006 340 567 www.circadlan.com.au