Opthea Ltd — Major Shareholding Notification 2024

Jul 18, 2024

Form 604 Corporations Act 2001 Section 671B Notice of change of interests of substantial holder	Form 604 Corporations Act 2001 Section 671B Notice of change of interests of substantial holder	Form 604 Corporations Act 2001 Section 671B Notice of change of interests of substantial holder	Form 604 Corporations Act 2001 Section 671B Notice of change of interests of substantial holder	Form 604 Corporations Act 2001 Section 671B Notice of change of interests of substantial holder	Form 604 Corporations Act 2001 Section 671B Notice of change of interests of substantial holder
To Company Name/Scheme ACN/ARSN 1. Details of substantial holder (1) Name ACN/ARSN (if applicable) The previous notice was given to the company on The previous notice was dated 2. Previous and present voting power The total number of votes attached to all the voting shares in the company or voting interes when last required, and when now required, to give a substantial holding notice to the com There was a change in the interests of the substantial holder on		OPTHEA L		TD (OPT)
		006 340 56		7
		Regal Fund (see Annex		s Management Pty Limited and ure 1)		its associates
		-
		ts in the schem pany or scheme,		17/07/2024 25/06/2024 21/06/2024 e that the substantial holder or an associa are as follows:		Class and number of securities Person's votes 145,317,367 ORDINARY 145,317,367 778,373 ADS 6,226,984 3,980,049 ORDINARY 3,980,049 46,242,896 ORDINARY 46,242,896 646,058 ADS 5,168,464 60,000,000 ORDINARY 60,000,000 2,114,754 ORDINARY 2,114,754 51,180,287 ORDINARY 51,180,287 770,942 ADS 6,167,536 1.89% any or scheme, since the substantial 30.99% otice Voting power (5) te (2) had a relevant interest (3) in d number of securities
Class of securities (4)	Previous notice			Current n		otice
	Person's votes	Voting power (5)		Person's votes		Voting power (5)
ORDINARY	289,736,603	*26.55%		381,559,238		*30.99%
ADS each representing 8 ordinaryshares	2,907,403	*2.13%		2,907,403		*1.89%
The % substantial is bas 3. Changes in relevant* Particulars of each change in, holder was last required to giv	ed on the shares on issue of 1,231,094,617 as disclo interests or change in the nature of, a relevant interest of the substant e a substantial holding notice to the company or scheme are	sed by the Company on 17-07-2024. ial holder or an associate in voting securities of the comp as follows:
Holder of relevant interest	Date of acquisition	Consideration (9)			Class an	d number of securities
	See Annexure 2
4. Present relevant int Particulars of each releva	erests nt interest of the substantial holder in voting securitie	s after the change are as follows:
Holder of relevant interest	Registered holder of securities		Person entitled to be registered as holder (8)		Nature of relevant interest (6)	Class and number of securities	Person's votes
Regal Funds Management Pty Ltd and its associates	UBS Nominees Pty Ltd		UBS AG, Australia Branch		HOLDER OF SHARES	145,317,367 ORDINARY	145,317,367
	UBS Securities LLC & Citibank					778,373 ADS	6,226,984
Regal Funds Management Pty Ltd and its associates	HSBC Custody Nominees (Australia) Limited A/C 2		Morgan Stanley & Co Intl Plc		HOLDER OF SHARES	3,980,049 ORDINARY	3,980,049
Regal Funds Management Pty Ltd and its associates	HSBC CUSTODY NOMINEES (AUSTRALIA) LIMITED		GOLDMAN SACHS INTERNATIONAL, LONDON		HOLDER OF SHARES	46,242,896 ORDINARY	46,242,896
	Goldman Sachs International					646,058 ADS	5,168,464
	HSBC CUSTODY NOMINEES (AUSTRALIA) LIMITED-GSC ECSA	O	GOLDMAN SACHS & CO. LLC			60,000,000 ORDINARY	60,000,000
Regal Funds Management Pty Ltd and its associates	J.P. MORGAN NOMINEES AUSTRALIA LTD (AUSTRALIA) LIMITED		J.P MORGAN NOMINEES AUSTRALIA LTD		HOLDER OF SHARES	2,114,754 ORDINARY	2,114,754
Regal Funds Management Pty Ltd and its associates	Merrill Lynch (Australia) Nominees Pty Limited		Merrill Lynch International Limited		HOLDER OF SHARES	51,180,287 ORDINARY	51,180,287
	Merrill Lynch Pierce Fenner & Smith					770,942 ADS	6,167,536

	Previous notice		Current notice	Current notice
Class of securities (4)	Person's votes	Voting power (5)	Person's votes		Voting power (5)
ORDINARY	289,736,603	*26.55%	381,559,238		*30.99%
ADS each representing 8 ordinaryshares	2,907,403	*2.13%	2,907,403		*1.89%

Holder of relevant interest	Date of acquisition	Consideration (9)	Class and number of securities
	See Annexure 2

Holder of relevant interest	Registered holder of securities	Person entitled to be registered as holder (8)	Nature of relevant interest (6)	Class and number of securities	Person's votes
	UBS Nominees Pty Ltd			145,317,367 ORDINARY	145,317,367
Regal Funds Management Pty Ltd and its associates	UBS Securities LLC & Citibank	UBS AG, Australia Branch	HOLDER OF SHARES	778,373 ADS	6,226,984
Regal Funds Management Pty Ltd and its associates	HSBC Custody Nominees (Australia) Limited A/C 2	Morgan Stanley & Co Intl Plc	HOLDER OF SHARES	3,980,049 ORDINARY	3,980,049
	HSBC CUSTODY NOMINEES (AUSTRALIA) LIMITED			46,242,896 ORDINARY	46,242,896
		GOLDMAN SACHS
		INTERNATIONAL, LONDON
Regal Funds Management Pty Ltd and its associates	Goldman Sachs International		HOLDER OF SHARES	646,058 ADS	5,168,464
	HSBC CUSTODY NOMINEES (AUSTRALIA) LIMITED-GSCO ECSA	GOLDMAN SACHS & CO. LLC		60,000,000 ORDINARY	60,000,000
Regal Funds Management Pty Ltd and its associates	J.P. MORGAN NOMINEES AUSTRALIA LTD (AUSTRALIA) LIMITED	J.P MORGAN NOMINEES AUSTRALIA LTD	HOLDER OF SHARES	2,114,754 ORDINARY	2,114,754
Regal Funds Management	Merrill Lynch (Australia) Nominees Pty Limited	Merrill Lynch International	HOLDER OF	51,180,287 ORDINARY	51,180,287
Pty Ltd and its associates	Merrill Lynch Pierce Fenner & Smith	Limited	SHARES	770,942 ADS	6,167,536

Regal Funds Management Pty Ltd and its associates	J.P. MORGAN PRIME NOMINEES LTD	J.P. MORGAN SECURITIES PLC	HOLDER OF SHARES	72,723,885 ORDINARY	72,723,885
	J.P. MORGAN SECURITIES LLC	J.P. MORGAN SECURITIES LLC		712,030 ADS	5,696,240

5. Changes in associatio The persons who have bec in relation to voting interest	n ome associ s in the com	is form are as follows: capacity ates (2) of, ceased to be associates of, or have changed the nature of their association (9) with, the substantial holder pany or scheme are as follows: S MANAGEMENT PTY LIMITED LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000 TNERS LIMITED 100% OWNER OF REGAL FUNDS MANAGEMENT PTY LIMITED ESTMENTS LIMITED LISTED INVESTMENT COMPANY WHOSE INVESTMENT MANAGEMENT DECISIONS ARE CONTROLLED BY REGAL ASIAN INVESTMENTS MANAGEMENT PTY LIMITED S MANAGEMENT PTY LIMITED 100% OWNED BY REGAL PARTNERS LIMITED ARSN (if applicable) Nature of association ame TNERS LIMITED Address LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000 KennyHo AGEMENT PTY LIMITED LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000 ESTMENTS LIMITED LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000 CompanySecretary
Nam	e and ACN/	ARSN (if applicable)	Nature of association
R	EGAL PAR	TNERS LIMITED	100% OWNER OF REGAL FUNDS MANAGEMENT PTY LIMITED
REGAL	ASIAN INV	ESTMENTS LIMITED	LISTED INVESTMENT COMPANY WHOSE INVESTMENT MANAGEMENT DECISIONS ARE CONTROLLED BY REGAL ASIAN INVESTMENTS MANAGEMENT PTY LIMITED
REGAL ASIAN INV	ESTMENT	S MANAGEMENT PTY LIMITED	100% OWNED BY REGAL PARTNERS LIMITED
6. Addresses The addresses of persons	named in th
	N	ame	Address
REGAL FU	NDS MAN	AGEMENT PTY LIMITED	LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000
R	EGAL PAR	TNERS LIMITED	LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000
REGAL	ASIAN INV	ESTMENTS LIMITED	LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000
REGAL ASIAN INV	ESTMENT	S MANAGEMENT PTY LIMITED	LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000
	print name sign here
		date 19/07/2024

5. Changes in association

The persons who have become associates (2) of, ceased to be associates of, or have changed the nature of their association (9) with, the substantial holder in relation to voting interests in the company or scheme are as follows:

Name and ACN/ARSN (if applicable)	Nature of association
	100% OWNER OF REGAL FUNDS MANAGEMENT PTY
REGAL PARTNERS LIMITED
	LIMITED
	LISTED INVESTMENT COMPANY WHOSE INVESTMENT
	MANAGEMENT DECISIONS ARE CONTROLLED BY
REGAL ASIAN INVESTMENTS LIMITED
	REGAL ASIAN INVESTMENTS MANAGEMENT PTY
	LIMITED
REGAL ASIAN INVESTMENTS MANAGEMENT PTY LIMITED	100% OWNED BY REGAL PARTNERS LIMITED

6. Addresses

The addresses of persons named in this form are as follows:

Name	Address
REGAL FUNDS MANAGEMENT PTY LIMITED	LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY
	NSW 2000
REGAL PARTNERS LIMITED	LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY
	NSW 2000
REGAL ASIAN INVESTMENTS LIMITED	LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY
	NSW 2000
REGAL ASIAN INVESTMENTS MANAGEMENT PTY LIMITED	LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY
	NSW 2000

Signature

Annexure 1

Details of Substantial Holders

ACN	Name
107 576 821	REGAL FUNDS MANAGEMENT PTY LIMITED
129 188 450	REGAL PARTNERS LIMITED
635 179 538	REGAL ASIAN INVESTMENTS MANAGEMENT PTY LIMITED
635 219 484	REGAL ASIAN INVESTMENTS LIMITED

Annexure 2

Annexure 2	Annexure 2	Annexure 2	Annexure 2	Annexure 2	Annexure 2	Annexure 2
Changes in Relevant Interests Date Nature of Change Consideration given in relation to change Number of securities affected Class of securities Persons votes affected 27/06/2024 Sell 360000.00 1000000 Ordinary 1000000 27/06/2024 Buy 360000.00 1000000 Ordinary 1000000 2/07/2024 Sell 690000.00 2000000 Ordinary 2000000 2/07/2024 Buy 690000.00 2000000 Ordinary 2000000 Regal Funds Management Pty Limited (and Regal Partners Limited by virtue of control of Regal Funds Management Pty Limited) Regal Funds Management Pty Limited (and Regal Partners Limited by virtue of control of Regal Funds Management Pty Limited) Person whose relevant interest changed Regal Funds Management Pty Limited (and Regal Partners Limited by virtue of control of Regal Funds Management Pty Limited) Regal Funds Management Pty Limited (and Regal Partners Limited by virtue of control of Regal Funds Management Pty Limited)
5/07/2024 Sell 491466.65 1424541 Ordinary 1424541 5/07/2024 Buy 491466.65 1424541 Ordinary 1424541 17/07/2024 Buy 36729054.00 91822635 Ordinary 91822635 Regal Funds Management Pty Limited (and Regal Partners Limited by virtue of control of Regal Funds Management Pty Limited) Regal Funds Management Pty Limited (and Regal Partners Limited by virtue of control of Regal Funds Management Pty Limited) Regal Funds Management Pty Limited (and Regal Partners Limited by virtue of control of Regal Funds Management Pty Limited)
5/07/2024	Regal Funds Management Pty Limited (and Regal Partners Limited by virtue of control of Regal Funds Management Pty Limited)	Sell	491466.65	1424541	Ordinary	1424541
5/07/2024	Regal Funds Management Pty Limited (and Regal Partners Limited by virtue of control of Regal Funds Management Pty Limited)	Buy	491466.65	1424541	Ordinary	1424541
17/07/2024	Regal Funds Management Pty Limited (and Regal Partners Limited by virtue of control of Regal Funds Management Pty Limited)	Buy	36729054.00	91822635	Ordinary	91822635