Opthea Ltd — Major Shareholding Notification 2022

Aug 28, 2022

Form 604 Corporations Act 2001 Section 671B Notice of change of interests of substantial holder	Form 604 Corporations Act 2001 Section 671B Notice of change of interests of substantial holder	Form 604 Corporations Act 2001 Section 671B Notice of change of interests of substantial holder	Form 604 Corporations Act 2001 Section 671B Notice of change of interests of substantial holder	Form 604 Corporations Act 2001 Section 671B Notice of change of interests of substantial holder	Form 604 Corporations Act 2001 Section 671B Notice of change of interests of substantial holder
To Company Name/Scheme ACN/ARSN 1. Details of substantial holder (1) Name ACN/ARSN (if applicable) The previous notice was given to the compa The previous notice was dated 2. Previous and present voting power The total number of votes attached to all the voting (3) in when last required, and when now required, t There was a change in the interests of the s	ny on shares in the company or voting interests in o give a substantial holding notice to the com ubstantial holder on	OPTHEA L		TD (OPT)
		006 340 56		7
		Regal Fund (see Annex		s Management Pty Limited ure 1)		and its associates
		-
		the scheme that pany or schem		25/08/2022 7/06/2022 3/06/2022 the substantial holder or an assoc e, are as follows:		Class and number of securities Person's votes 28,223,867 Ordinary 28,233,867 1,340,637 ADS 10,725,096 1,286,776 Ordinary 1,286,776 13,976,823 Ordinary 15,502,503 1,543,153 ADS 12,345,224 3,091,085 Ordinary 4,296,457 d number of securities NAGEMENT iate (2) had a relevant interest notice Voting power (5) pany or scheme, since the 12.18% 5.70% (9) with, the substantial
Class of securities (4)	Previous notice			Current		notice
	Person's votes	Voting power (5)		Person's votes		Voting power (5)
ORDINARY	43,701,022	12.41%		49,319,603		*12.18%
ADS each representing 8 ordinary shares	2,883,790	6.55%		2,883,790		*5.70%
The % substantial is based on the shares o 3. Changes in relevant interests* Particulars of each change in, or change in the nat substantial holder was last required to give a subst	n issue of 404,975,423 as disclosed by the Company on 24-08-2022. ure of, a relevant interest of the substantial holder or an associate in voting securities of the com antial holding notice to the company or scheme are as follows:
Holder of relevant interest	Date of acquisition	Consideration (9)			Class an	d number of securities
	See Annexure 2
4. Present relevant interests Particulars of each relevant interest of the su	bstantial holder in voting securities after the change are as follows:
Holder of relevant interest	Registered holder of securities		Person entitled to be registered as holder (8)		Nature of relevant interest (6)	Class and number of securities	Person's votes
Regal Funds Management Pty Ltd and its associates	UBS Nominees Pty Ltd		UBS AG, Australia Branch		HOLDER OF SHARES	28,223,867 Ordinary	28,233,867
	UBS Securities LLC & Citibank					1,340,637 ADS	10,725,096
Regal Funds Management Pty Ltd and its associates	HSBC Custody Nominees (Australia) Limited A/C 2		Morgan Stanley & Co Intl Plc		HOLDER OF SHARES	1,286,776 Ordinary	1,286,776
Regal Funds Management Pty Ltd and its associates	Merrill Lynch (Australia) Nominees Pty Limited		Merrill Lynch International Limited		HOLDER OF SHARES	13,976,823 Ordinary	15,502,503
	Merrill Lynch Pierce Fenner & Smith					1,543,153 ADS	12,345,224
Regal Funds Management Pty Ltd and its associates	J.P. MORGAN PRIME NOMINEES LTD		J.P MORGAN SECURITIES PLC		HOLDER OF SHARES	3,091,085 Ordinary	4,296,457
5. Changes in association The persons who have become associates holder in relation to voting interests in the co	(2) of, ceased to be associates of, or have changed the nature of their association mpany or scheme are as follows:					NAGEMENT (9) with, the substantial
Name and ACN/AR	SN (if applicable)		Nature of association
REGAL PARTN	ERS LIMITED		100% OWNER OF REGAL FUNDS MA PTY LIMITED			NAGEMENT

	Previous notice		Current notice	Current notice
Class of securities (4)	Person's votes	Voting power (5)	Person's votes		Voting power (5)
ORDINARY	43,701,022	12.41%	49,319,603		*12.18%
ADS each representing 8 ordinary shares	2,883,790	6.55%	2,883,790		*5.70%

Holder of relevant interest	Date of acquisition		Consideration (9)	Class and number of securities	Class and number of securities	Class and number of securities
	See Annexure 2
4. Present relevant interests
Particulars of each relevant interest of the substantial holder in voting securities after the change are as follows:
Holder of relevant interest	Registered holder of securities		Person entitled to be registered as holder (8)	Nature of relevant interest (6)	Class and number of securities	Person's votes
Regal Funds Management Pty Ltd and its associates	UBS Securities LLC & Citibank UBS Nominees Pty Ltd		UBS AG, Australia Branch	HOLDER OF SHARES	28,223,867 Ordinary 1,340,637 ADS	28,233,867 10,725,096
Regal Funds Management Pty Ltd and its associates	HSBC Custody Nominees (Australia) Limited A/C 2		Morgan Stanley & Co Intl Plc	HOLDER OF SHARES	1,286,776 Ordinary	1,286,776
Regal Funds Management Pty Ltd and its	Merrill Lynch (Australia) Nominees Pty Limited		Merrill Lynch International	HOLDER OF	13,976,823 Ordinary	15,502,503
associates	Merrill Lynch Pierce Fenner & Smith		Limited	SHARES	1,543,153 ADS	12,345,224
Regal Funds Management Pty Ltd and its associates	J.P. MORGAN PRIME NOMINEES LTD		J.P MORGAN SECURITIES PLC	HOLDER OF SHARES	3,091,085 Ordinary	4,296,457
5. Changes in association
The persons who have become associates	(2) of, ceased to be associates of, or have changed the nature of their association				(9) with, the substantial
holder in relation to voting interests in the company or scheme are as follows:
Name and ACN/ARSN (if applicable)			Nature of association
REGAL PARTNERS LIMITED			100% OWNER OF REGAL	FUNDS MANAGEMENT
			PTY LIMITED

6. Addresses The addresses of persons named in this form are as follo	6. Addresses The addresses of persons named in this form are as follo	ws: capacity CompanySecretary Address LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000 KennyHo LIMITED LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000	ws: capacity CompanySecretary Address LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000 KennyHo LIMITED LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000	ws: capacity CompanySecretary Address LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000 KennyHo LIMITED LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000	ws: capacity CompanySecretary Address LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000 KennyHo LIMITED LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000	ws: capacity CompanySecretary Address LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000 KennyHo LIMITED LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000	ws: capacity CompanySecretary Address LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000 KennyHo LIMITED LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000
Name			Address
REGAL FUNDS MANAGEMENT PTY		LIMITED	LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000
REGAL PARTNERS LIMITED			LEVEL 47, GATEWAY, 1 MACQUARIE PLACE, SYDNEY NSW 2000
Signature print name sign here Annexure 1 Details of Substantial Holders
		date 29/08/2022
		Nature of Change Consideration given in relation to change Number of securities affected Class of securities Persons votes affected Buy 24730.42 23564 Ordinary 23564 Buy 21000.00 20000 Ordinary 20000 Buy 82964.04 74474 Ordinary 74474 Buy 172555.53 147370 Ordinary 147370 Buy 167547.34 149090 Ordinary 149090 Buy 19790.34 15864 Ordinary 15864 Sell 42065.14 36741 Ordinary 36741 Buy 6385937.35 5552989 Ordinary 5552989 Sell 383793.93 328029 Ordinary 328029 Holding diluted due to the issue of 52,822,881 shares on the 25th of August, 2022. TED egal Partners Limited by virtue ment Pty Limited) egal Partners Limited by virtue ment Pty Limited) egal Partners Limited by virtue ment Pty Limited) egal Partners Limited by virtue ment Pty Limited) egal Partners Limited by virtue ment Pty Limited) egal Partners Limited by virtue ment Pty Limited) rest changed egal Partners Limited by virtue ment Pty Limited) egal Partners Limited by virtue ment Pty Limited) egal Partners Limited by virtue ment Pty Limited) egal Partners Limited by virtue ment Pty Limited)
ACN	Name
107 576 821	REGAL FUNDS MANAGEMENT PTY LIMI	TED
129 188 450	REGAL PARTNERS LIMITED
Annexure 2 Changes in relevant interests [ordinary]
Date	Person whose relevant inte	rest changed	Nature of Change	Consideration given in relation to change	Number of securities affected	Class of securities	Persons votes affected
16/06/2022	Regal Funds Management Pty Limited (and R of control of Regal Funds Manage	egal Partners Limited by virtue ment Pty Limited)	Buy	24730.42	23564	Ordinary	23564
22/06/2022	Regal Funds Management Pty Limited (and R of control of Regal Funds Manage	egal Partners Limited by virtue ment Pty Limited)	Buy	21000.00	20000	Ordinary	20000
24/06/2022	Regal Funds Management Pty Limited (and R of control of Regal Funds Manage	egal Partners Limited by virtue ment Pty Limited)	Buy	82964.04	74474	Ordinary	74474
28/06/2022	Regal Funds Management Pty Limited (and R of control of Regal Funds Manage	egal Partners Limited by virtue ment Pty Limited)	Buy	172555.53	147370	Ordinary	147370
29/06/2022	Regal Funds Management Pty Limited (and R of control of Regal Funds Manage	egal Partners Limited by virtue ment Pty Limited)	Buy	167547.34	149090	Ordinary	149090
16/08/2022	Regal Funds Management Pty Limited (and R of control of Regal Funds Manage	egal Partners Limited by virtue ment Pty Limited)	Buy	19790.34	15864	Ordinary	15864
24/08/2022	Regal Funds Management Pty Limited (and R of control of Regal Funds Manage	egal Partners Limited by virtue ment Pty Limited)	Sell	42065.14	36741	Ordinary	36741
25/08/2022	Regal Funds Management Pty Limited (and R of control of Regal Funds Manage	egal Partners Limited by virtue ment Pty Limited)	Buy	6385937.35	5552989	Ordinary	5552989
25/08/2022	Regal Funds Management Pty Limited (and R of control of Regal Funds Manage	egal Partners Limited by virtue ment Pty Limited)	Sell	383793.93	328029	Ordinary	328029
25/08/2022	Regal Funds Management Pty Limited (and R of control of Regal Funds Manage	egal Partners Limited by virtue ment Pty Limited)	Holding diluted due to the issue of 52,822,881 shares on the 25th of August, 2022.