Opthea Ltd — Director's Dealing 2024

Dec 16, 2024

Appendix 3Y Change of Director’s Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/09/01 Amended 01/01/11

Name of entity: Opthea Limited

ABN 32 006 340 567

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	Anshul Thakral
Date of last notice	21 December 2023

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Direct or indirect interest	Direct
Nature of indirect interest(including registered holder)Note: Provide details of the circumstances giving rise to the relevantinterest.	Anshul Thakral.
Date of change	17 December 2024
No. of securities held prior to change	1,000,000 unquoted options to acquirefully paid ordinary shares at an exerciseprice of $0.60, expiring on 29 November2033, granted under the LTIP
Class	Options
Number acquired	2,000,000 unquoted options to acquirefully paid ordinary shares at an exerciseprice of $0.655, expiring on 14 November2034, granted under the LTIP

• See chapter 19 for defined terms.

01/01/2011

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Appendix 3Y Change of Director’s Interest Notice

Number disposed	nil
Value/ConsiderationNote: If consideration is non-cash, provide details and estimatedvaluation	nil.
No. of securities held after change	Direct:1,000,000 unquoted options to acquirefully paid ordinary shares at an exerciseprice of $0.60, expiring on 29 November2033, granted under the LTIP2,000,000 unquoted options to acquirefully paid ordinary shares at an exerciseprice of $0.655, expiring on 14 November2034, granted under the LTIP
Nature of changeExample: on-market trade, off-market trade, exercise of options, issueof securities under dividend reinvestment plan, participation in buy-back	Issuance of unquoted options

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

==> picture [408 x 276] intentionally omitted <==

----- Start of picture text ----- Detail of contract N/ANature of interest N/AName of registered holder N/A(if issued securities)Date of change N/ANo. and class of securities to which N/Ainterest related prior to changeNote: Details are only required for a contract inrelation to which the interest has changedInterest acquired N/AInterest disposed N/AValue/Consideration N/ANote: If consideration is non-cash, provide detailsand an estimated valuation----- End of picture text -----

• See chapter 19 for defined terms.

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Appendix 3Y Change of Director’s Interest Notice

Interest after change N/A

Part 3 –[+] Closed period

Part 3 –+Closed period
Were the interests in the securities or contracts detailedabove traded during a+closed period where prior writtenclearance was required?	N/A
If so, was prior written clearance provided to allow thetrade to proceed during this period?	N/A
If prior written clearance was provided, on what date wasthis provided?	N/A

• See chapter 19 for defined terms.

01/01/2011

Appendix 3Y Page 3