Opthea Ltd — Director's Dealing 2014

Nov 18, 2014

Appendix 3Y Change of Director’s Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/09/01 Amended 01/01/11

Name of entity Circadian Technologies Limited

ABN 32 006 340 567

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director Megan Baldwin

Date of last notice 21 February 2014

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Direct or indirect interest	Direct
Nature of indirect interest(including registered holder)Note: Provide details of the circumstances giving rise to the relevantinterest.	N/A
Date of change	12 November 2014
No. of securities held prior to change	10,674 ordinary shares, fully paid.200,000 Employee conditionalperformance rights (unlisted securities –CIRAM) Exercise price $Nil, expiry 31March 2015
Class	Ordinary shares, fully paid, listed optionsand performance rights (unlistedsecurities)
Number acquired	23,000 ordinary shares, fully paid.11,500 listed options, exercise price $0.27,expiry25November 2018
Number disposed	NIL
Value/ConsiderationNote: If consideration is non-cash, provide details and estimatedvaluation	$4,025.00

• See chapter 19 for defined terms.

01/01/2011 Appendix 3Y Page 1

Appendix 3Y Change of Director’s Interest Notice

	6 ordinar shares full aid
No of securities held after change
.	33,74 y y p.11,500 listed options, exercise price $0.27,expiry 25 November 2018.200,000 Employee conditionalperformance rights (unlisted securities –CIRAM)Exercise price $Nil, expiry 31 March 2015
Nature of changeExample: on-market trade, off-market trade, exercise of options,issue of securities under dividend reinvestment plan, participation inbuy-back	Ordinary shares and accompanying listedoptions acquired pursuant toparticipation in non-renounceable 2 for 5rights issue announced on 6 October 2014

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

	Detail of contract	N/A	N/A	N/A	N/A
	Nature of interest	N/A
	Name of registered holder(if issued securities)	N/A
	Date of change	N/A
	No. and class of securities to whichinterest related prior to changeNote: Details are only required for a contract inrelation to which the interest has changed	N/A
	Interest acquired	N/A
	Interest disposed	N/A
	Value/ConsiderationNote: If consideration is non-cash, provide detailsand an estimated valuation	N/A
	**Interest after change **	N/A

Part 3 –[+] Closed period

Part 3 –+Closed period
Were the interests in the securities or contracts detailedabove traded during a+closed period where prior writtenclearance was required?	N0
If so, was prior written clearance provided to allow the tradeto proceed during this period?	N/A
If prior written clearance was provided, on what date was thisprovided?	N/A

• See chapter 19 for defined terms.

Appendix 3Y Page 2

01/01/2011