Opthea Ltd — Director's Dealing 2013

May 26, 2013

Appendix 3Y Change of Director’s Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/9/2001.Amended 1/1/2011

Name of entity CIRCADIAN TECHNOLOGIES LIMITED ABN 32 006 340 567

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	ROBERT KLUPACS
Date of last notice	22 MAY 2013

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Direct or indirect interest	DIRECT INTEREST
Nature of indirect interest (including registered holder) Note: Provide details of the circumstances giving rise to the relevant interest.	N/A
Date of change	24 MAY 2013
No. of securities held prior to change	DIRECT INTEREST – 475,453 ORDINARY SHARES 520,000 EMPLOYEE CONDITIONAL PERFORMANCE RIGHTS (UNLISTED SECURITIES) EXERCISE PRICE: $0.00 FIRST EXERCISE DATE: Subject to satisfaction of certain performance milestones. EXPIRY DATE: 31/3/2015 (CIRAM)
Class	ORDINARY SHARES
Number acquired	5,000 ORDINARY SHARES

• See chapter 19 for defined terms.

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Appendix 3Y Change of Director’s Interest Notice

Number disposed	NIL
Value/Consideration Note: If consideration is non-cash, provide details and estimated valuation	TOTAL CONSIDERATION - $1,250
No. of securities held after change	DIRECT INTEREST – 476,703 ORDINARY SHARES 520,000 EMPLOYEE CONDITIONAL PERFORMANCE RIGHTS (UNLISTED SECURITIES) EXERCISE PRICE: $0.00 FIRST EXERCISE DATE: Subject to satisfaction of certain performance milestones. EXPIRY DATE: 31/3/2015 (CIRAM)
Nature of change Example: on-market trade, off-market trade, exercise of options, issue of securities under dividend reinvestment plan, participation in buy- back	On Market Trade

• See chapter 19 for defined terms.

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Appendix 3Y Change of Director’s Interest Notice

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

Detail of contract	-
Nature of interest	-
Name of registered holder (if issued securities)	-
Date of change	-
No. and class of securities to which interest related prior to change Note: Details are only required for a contract in relation to which the interest has changed	-
Interest acquired	-
Interest disposed	-
Value/Consideration Note: If consideration is non-cash, provide details and an estimated valuation	-
Interest after change	-

Part 3 – + Closed period

Were the interests in the securities or contracts detailed above traded during a+closed period where prior written clearance was required?	No
If so, was prior written clearance provided to allow the trade to proceed during this period?	Not applicable
If prior written clearance was provided, on what date was this provided?	Not applicable

• See chapter 19 for defined terms.

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