Opthea Ltd — Director's Dealing 2013

Dec 5, 2013

Appendix 3X Initial Director’s Interest Notice

Rule 3.19A.1

Appendix 3X

Initial Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/9/2001.

Name of entity CIRCADIAN TECHNOLOGIES LIMITED ABN 32 006 340 567

We (the entity) give ASX the following information under listing rule 3.19A.1 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	Russell John Howard
Date of appointment	03 December 2013

Part 1 - Director’s relevant interests in securities of which the director is the registered holder In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Number & class of securities

NIL

Part 2 – Director’s relevant interests in securities of which the director is not the registered holder

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

	Name of holder & nature of interestNote: Provide details of the circumstances givingrise to the relevant interest.NIL	Number & class of SecuritiesNIL

• See chapter 19 for defined terms.

30/9/2001

Appendix 3X Page 1

Appendix 3X Initial Director’s Interest Notice

Part 3 – Director’s interests in contracts

Detail of contract	NIL
Nature of interest	NIL
Name of registered holder(if issued securities)	NIL
No. and class of securities to whichinterest relates	NIL

• See chapter 19 for defined terms.

30/9/2001

Appendix 3X Page 2