Opthea Ltd — Director's Dealing 2013

Dec 9, 2013

Appendix 3Z Final Director’s Interest Notice

Rule 3.19A.3

Appendix 3Z

Final Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/9/2001.

Name of entity CIRCADIAN TECHNOLOGIES LIMITED ABN 32 006 340 567

We (the entity) give ASX the following information under listing rule 3.19A.3 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of director	ROBERT KLUPACS
Date of last notice	27 MAY 2013
Date that director ceased to be director	03 DECEMBER 2013

Part 1 – Director’s relevant interests in securities of which the director is the registered holder In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Number & class of securities

480,453** Fully paid ordinary shares

520,000 Employee conditional performance rights (unlisted securities - CIRAM) Exercise price = $0.00, Expiry date = 31/03/2015

• ** The last notice lodged 27 May 2013 incorrectly showed holdings of 476,703 fully paid ordinary shares due to a clerical error.

• See chapter 19 for defined terms.

Appendix 3Z Page 1

11/3/2002

Appendix 3Z Final Director’s Interest Notice

Part 2 – Director’s relevant interests in securities of which the director is not the registered holder

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

	Name of holder & nature of interestNote: Provide details of the circumstances giving rise tothe relevant interestNIL	Number & class of securitiesNIL

Part 3 – Director’s interests in contracts

Detail of contract	NIL
Nature of interest	NIL
Name of registered holder(if issued securities)	NIL
No. and class of securities towhich interest relates	NIL

• See chapter 19 for defined terms.

Appendix 3Z Page 2

11/3/2002