Opthea Ltd — Director's Dealing 2009

Apr 23, 2009

Appendix 3Y Change of Director’s Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director’s Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX’s property and may be made public.

Introduced 30/9/2001.

Name of entity CIRCADIAN TECHNOLOGIES LIMITED ABN 32 006 340 567

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of Director	DOMINIQUE GAYLE FISHER
Date of last notice	19 DECEMBER 2007

Part 1 - Change of director’s relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Note: In the case of a company, interests which come within paragraph (i) of the definition of “notifiable interest of a director” should be disclosed in this part.

Direct or indirect interest	INDIRECT INTEREST
Nature of indirect interest(including registered holder)Note: Provide details of the circumstances giving rise to the relevantinterest.	THE STOCKDALE FISHERSUPERANNUATION FUND(Ms Fisher is a beneficiary of thissuperannuation fund)
Date of change	23 April 2009
No. of securities held prior to change	INDIRECT INTEREST:**MERINA PTY LTD -**17,500 ordinaryshares, fully paidTHE STOCKDALE FISHER**SUPERANNUATION FUND –**50,000ordinary shares, fully paid
Class	ORDINARY SHARES
Number acquired	50,000 shares

• See chapter 19 for defined terms.

Appendix 3Y Page 1

11/3/2002

Appendix 3Y Change of Director’s Interest Notice

Number disposed		-
Value/ConsiderationNote: If consideration is non-cash, provide details and estimatedvaluation		$0.85 per share
No. of securities held after change		INDIRECT INTEREST**MERINA PTY LTD -**17,500 ordinaryshares, fully paidTHE STOCKDALE FISHER**SUPERANNUATION FUND –**100,000ordinary shares, fully paid
Nature of changeExample: on-market trade, off-market trade, exercise of options, issue ofsecurities under dividend reinvestment plan, participation in buy-back		ON-MARKET TRADE

Part 2 – Change of director’s interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of “notifiable interest of a director” should be disclosed in this part.

Detail of contract	-
Nature of interest	-
Name of registered holder(if issued securities)	-
Date of change	-
No. and class of securities to whichinterest related prior to changeNote: Details are only required for a contract in relationto which the interest has changed	-
Interest acquired	-
Interest disposed	-
Value/ConsiderationNote: If consideration is non-cash, provide details andan estimated valuation	-
Interest after change	-

• See chapter 19 for defined terms.

Appendix 3Y Page 2

11/3/2002