Opthea Ltd — Capital/Financing Update 2025

Aug 7, 2025

Appendix 2A - Application for quotation of securities

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Announcement Summary

Entity name

OPTHEA LIMITED

Announcement Type

New announcement

Date of this announcement

Friday August 08, 2025

The +securities to be quoted are:

+Securities previously issued under an +employee incentive scheme where the restrictions on transfer have ceased or are about to cease

Total number of +securities to be quoted

ASX +security		Number of +securities to
code	Security description	be quoted	Issue date
OPT	ORDINARY FULLY PAID	29,672	29/01/2025

Refer to next page for full details of the announcement

Appendix 2A - Application for quotation of securities

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Appendix 2A - Application for quotation of securities

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Part 1 - Entity and announcement details

1.1 Name of entity

OPTHEA LIMITED

We (the entity named above) apply for +quotation of the following +securities and agree to the matters set out in Appendix 2A of the ASX Listing Rules.

1.2 Registered number type

ABN

Registration number

32006340567

1.3 ASX issuer code

OPT

1.4 The announcement is

New announcement

1.5 Date of this announcement

8/8/2025

Appendix 2A - Application for quotation of securities

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Appendix 2A - Application for quotation of securities

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Part 2 - Type of Issue

2.1 The +securities to be quoted are:

+Securities previously issued under an +employee incentive scheme where the restrictions on transfer have ceased or are about to cease

2.2 The +class of +securities to be quoted is:

Additional +securities in a class that is already quoted on ASX ("existing class")

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Appendix 2A - Application for quotation of securities

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Part 3B - number and type of +securities to be quoted (existing class) where issue has not previously been notified to ASX in an Appendix 3B

Additional +securities to be quoted in an existing class as a result of transfer restrictions ceasing on an existing class FROM (Existing Class) ASX +security code and description OPTAC : ADS EXPIRING VARIOUS DATES EX VARIOUS PRICES

TO (Existing Class)
ASX +security code and description
OPT : ORDINARY FULLY PAID
Please state the number of +securities previously issued under the	And the date the restrictions on
+employee incentive scheme where the restrictions on transfer have ceased	transfer have ceased or will cease
or are about to cease
29,672	29/1/2025
Issue date
29/1/2025
Will the +securities to be quoted rank equally in all respects from their issue	date with the existing issued
+securities in that class?
Yes

Issue details Number of +securities to be quoted 29,672 Are the +securities being issued for a cash consideration? No Please describe the consideration being provided for the +securities Cash less conversion on exercise of ADS options Please provide an estimate (in AUD) of the value of the consideration being provided per +security for the +securities to be quoted 0.165000 Any other information the entity wishes to provide about the +securities to be quoted 'The Company advises that the late lodgement of this Appendix 2A is due to an isolated administrative oversight that was picked up as part of a reconciliation exercise. The Company considers that its current systems and practices remain adequate and appropriate to ensure compliance with the ASX Listing Rules.'

Appendix 2A - Application for quotation of securities

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Appendix 2A - Application for quotation of securities

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Part 4 - Issued capital following quotation

Following the quotation of the +securities the subject of this application, the issued capital of the entity will comprise:

The figures in parts 4.1 and 4.2 below are automatically generated and may not reflect the entity's current issued capital if other Appendix 2A, Appendix 3G or Appendix 3H forms are currently with ASX for processing.

4.1 Quoted +securities (total number of each +class of +securities quoted on ASX following the +quotation of the +securities subject of this application)

+securities subject of this application)
	Total number of
ASX +security code and description	+securities on issue
OPT : ORDINARY FULLY PAID	1,231,317,008
OPTOA : OPTION EXPIRING 31-AUG-2025	97,787,612
OPTOB : OPTION EXPIRING 30-JUN-2026	189,426,682

4.2 Unquoted +securities (total number of each +class of +securities issued but not quoted on ASX)

	Total number of
ASX +security code and description	+securities on issue
OPTAD : PERFORMANCE RIGHTS	2,900,000
OPTAL : OPTION EXPIRING 19-FEB-2034 EX USD 3.03	250,000
OPTAA : OPTION EXPIRING 31-MAR-2034 EX USD 4.14	27,000
OPTAB : OPTION EXPIRING VARIOUS DATES EX VARIOUS PRICES	41,370,950
OPTAC : ADS EXPIRING VARIOUS DATES EX VARIOUS PRICES	11,660,578

Appendix 2A - Application for quotation of securities

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