OPKO Health Inc.

Foreign Filer Report • Jul 28, 2017

_________ false

����� ���', ����	2 380
OPKO HEALTH, INC
Corporation no: 2279206	10802
- - -

	Israel Securities Authority			Tel Aviv Stock Exchange		C002 ( Public )		Reported via MAGNA:	28/07/2017
	www.isa.gov.il			www.tase.co.il				Reference:	2017-02-065374	Time of broadcast: 15:08 15:07:10

---

Immediate ReportRegulation 4 of the Securities Regulations, (Periodic and Immediate Reports of Foreign Corporation) 5761-2000

	The corporation is a foreign private issuer as defined by U.S. Securities Laws.

Attached hereto is a report onrelated party transaction

20170728Form4Signed.pdf

References of previous documents relating to this matter(the reference does not constitute incorporation by reference):
- - -
Stock Exchange/Market: NYSE	Date of revision of form structure: 16/07/2017
Address: Golda Meir 7 , Nes Ziona 7414002   Israel , Israel Tel: 08-9300051 , Fax: 08-9300091
E-mail address: yphilip@opko.com   Company site: Www.Opko.Com
Previous names of reporting entity:
Name of the Signatory: Philip Yifat Position of Signatory in the reporting corporation: General Counsel Name of Employer Company:
Address: Golda Meir 7 , Nes Ziona 7414002 Telephone: 08-9300051 Facsimile: 08-9300091 E-mail: yphilip@opko.com 1
Israel