Nyxoah SA

Major Shareholding Notification • Jun 3, 2024

1) Status of the notification

	Final
Identification number 0817-149-675	Name NYXOAH

3) Reason for the notification

Acquisition or disposal of voting securities or voting rights 2		+
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4) Notification by

2) Issuer

A parent undertaking or a controlling person

5) Persons subject to the notification requirement

Name	Address (for legal entities)
FMR LLC	The Corporation Trust Center, 1209 Orange Street, Wilmington, New Castle County, Delaware, 19801.	+

6) Persons that dispose of voting rights (only to be filled in if art. 7 of the Law applies)

Name	Address (for legal entities)
		A	+

Please continue entering the information in part II concerning the persons referred to in Sections 5 and 6

Part II

7) Date on which the threshold is crossed

8) Threshold that is crossed (in %)

If the holding has fallen below the lowest threshold, you have the option of not entering any numbers in Section 10

3

9) Denominator

34,060,390

Please enter the denominator before filling in the data

10) Notified details

A) Voting rights	After the transaction Previous notification
	# of voting rights	# of voting rights		% of voting rights
Holders of voting rights		Linked to securities	Not linked to the securities	Linked to securities	Not linked to the securities
FMR LLC	0	0		0.00%
FIAM LLC	0	258		0.00%
Fidelity Management & Research Company LLC	0	1,613,630		4.74%
Subtotal		1,613,888		4.74%
	TOTAL	1,613,888	0	4.74%	0.00%

0

0

0

² +

Start with "groups" of holders. Add subtotals with S, and then finish with the persons who are "alone". For groups, start with the ultimate controlling natural person or legal entity.

The totals, subtotals and % will be updated once you have clicked on .

After the transaction B) Equivalent financial instruments
Holders of equivalent financial instruments	Type of financial instrument		Expiration date Exercise period or date	# of voting rights that may be acquired if the instrument is exercised	% of voting rights	Settlement
Fidelity Management & Research Company LLC	Stock Loan			84,514	0.25%	physical	+
TOTAL				84,514	0.25%
The totals will be updated once you have clicked on
	TOTAL (A & B)				# of voting rights % of voting rights
			CALCULATE	1,698,402	4.99%

11) Full chain of controlled undertakings through which the holding is effectively held, if applicable

FIAM LLC is controlled by FIAM Holdings LLC. FIAM Holdings LLC, Fidelity Management & Research Company LLC are controlled by FMR LLC. FMR LLC is not a controlled undertaking.

12) In case of proxy voting for only one GM

				(DD/MM/YYYY)
Holder	will cease to hold / will hold again	0	voting rights as of

13) Additional information

The holdings attributed to the entities mentioned in heading 10 arise from holdings of various undertakings for collective investment that are managed by FIAM LLC, Fidelity Management & Research Company LLC, each of which are entities that are subsidiaries of and controlled by FMR LLC. The entities mentioned in heading 10 are the discretionary investment managers and exercise the voting rights at their discretion in the absence of specific instructions.

	Done at Dublin, Ireland
On		30/05/2024 (DD/MM/YYYY)
	Name & capacity Aaron Watson, Manager, Regulatory Reporting	Signature

For security reasons, the unsigned form in xlsx format should be transmitted to trp.fin@fsma.be. You can do this manually OR if you have MS Outlook at your disposal via the "Save & Send" button.

In addition, a signed copy in PDF format should also be transmitted.