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NYRADA INC. Major Shareholding Notification 2024

Nov 4, 2024

65469_rns_2024-11-04_6843e7a5-99f6-469f-a407-f3f209b19668.pdf

Major Shareholding Notification

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5 November 2024

Sydney, Australia

Notice of Change of Interests of a Substantial Securityholder

Nyrada Inc (ASX: NYR ), a drug discovery and development company focused on innovative Transient Receptor Potential Canonical (TRPC) ion channel blockers, further to the Deed Poll dated 6 January 2020 issued by the Company in favour of ASX Limited in respect of the Initial Public Offering of its Chess Depositary Interests (“CDIs”), provides a Notice of Change of Interests of a Substantial Holder in relation to Nyrada. Details of the change in CDIs (“Relevant Interests”) are as follows:

Name of Substantial Holder of Relevant Interests: Noxopharm Limited Date of change in the interests of the Substantial Holder : 4 November 2024

Previous and present voting power of Substantial Holder (through CHESS Depository Nominees Pty Ltd):

Nominees Pty Ltd): Nominees Pty Ltd):
Previous notice Present notice
Number of CDIs Voting power Number of CDIs Voting Power
33,373,245 18.60% 33,373,245 15.92%

Present Relevant Interests:

Holder of Relevant
Interest
Registered Holdings of
CDIs
Relevant
Interest
Number of
CDIs
Voting Power
Noxopharm Limited Noxopharm Limited 33,373,245 15.92%

-ENDS-

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Nyrada Inc. Level 3, 828 Pacific Highway, Gordon NSW 2072

ARBN 625 401 818

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About Nyrada Inc

Nyrada Inc. is a biotechnology company focused on the discovery and development of innovative small-molecule therapies, specifically targeting Transient Receptor Potential Canonical (TRPC) ion channels. The company’s lead candidate, NYR-BI03, has shown efficacy in both neuroprotection and cardioprotection, positioning it for a first-in-human Phase I clinical trial. Nyrada Inc. (ARBN 625 401 818) is incorporated in Delaware, USA, with limited liability for its stockholders.

www.nyrada.com

Authorised by Mr. John Moore, Chair on behalf of the Board.

Investor: Company Secretary: Dimitri Burshtein David Franks T: 02 9498 3390 T: 02 8072 1400 E: [email protected] E: [email protected]

Media Enquiries:

Catherine Strong Sodali & Co T: 02 8234 0111 E: [email protected]

Forward-Looking Statements

This announcement may contain forward-looking statements. You can identify these statements by the fact they use words such as “aim”, “anticipate”, “assume”, “believe”, “continue”, “could”, “estimate”, “expect”, “intend”, “may”, “plan”, “predict”, “project”, “plan”, “should”, “target”, “will” or “would” or the negative of such terms or other similar expressions. Forward-looking statements are based on estimates, projections, and assumptions made by Nyrada about circumstances and events that have not yet taken place. Although Nyrada believes the forward-looking statements to be reasonable, they are not certain. Forwardlooking statements involve known and unknown risks, uncertainties and other factors that are in some cases beyond the Company’s control that could cause the actual results, performance, or achievements to differ materially from those expressed or implied by the forward-looking statement.

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Nyrada Inc. Level 3, 828 Pacific Highway, Gordon NSW 2072

ARBN 625 401 818