NYRADA INC. — Capital/Financing Update 2025

Jul 30, 2025

Market Announcement

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31 July 2025

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Nyrada Inc (ASX: NYR) – Trading Halt

Trading in the securities of Nyrada Inc (‘NYR’) will be halted at the request of NYR, pending the release of an announcement by NYR.

Unless ASX decides otherwise, the securities will remain in trading halt until the earlier of:

• the commencement of normal trading on Monday, 4 August 2025; or

• the release of the announcement to the market.

NYR’s request for a trading halt is attached below for the information of the market.

Issued by

ASX Compliance

Market Announcement 1/1 ASX Customer Service Centre 131 279 | asx.com.au

31 July 2025 ASX Limited

#10941528v1

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31 July 2025

Sydney, Australia

ASX Limited Listings Compliance, Sydney 20 Bridge Street Sydney NSW 2000

Attention: Ms Yulia Gurdina (Senior Adviser, Listings Compliance (Sydney))

By Email Only: tradinghaltssydney@asx.com.au

Dear Ms Gurdina,

TRADING HALT REQUEST

Nyrada Inc [ASX:NYR] ( Company or Nyrada ) hereby requests a trading halt in relation to the Company’s Chess Depositary Interests (CDIs) quoted on the Australian Securities Exchange ( ASX ) in accordance with ASX Listing Rule 17.1.

The trading halt is requested pending an announcement by the Company to the market regarding a proposed capital raising ( the Purpose ).

In accordance with ASX Listing Rule 17.1, the Company provides the following information in relation to the request:

• The trading halt is necessary to assist Nyrada in managing its continuous disclosure obligations as the Company expects to make an announcement to the market in relation to the stated Purpose above.

• Nyrada requests that the trading halt remain in place until the earlier of commencement of normal trading on Monday, 4 August 2025, or when the announcement regarding the stated Purpose is released to the market.

• Nyrada is not aware of any reason why the trading halt should not be granted or of any further information necessary to inform the market about the trading halt.

For and on behalf of the Board of Nyrada Inc.

Yours faithfully,

David Franks

Company Secretary

-ENDS-

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Nyrada Inc. Level 3, 828 Pacific Highway, Gordon NSW 2072

ARBN 625 401 818

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About Nyrada Inc

Nyrada Inc. is a clinical stage biotechnology company focused on the discovery and development of innovative small-molecule therapies, specifically targeting Transient Receptor Potential Canonical (TRPC) ion channels. The company’s lead candidate, Xolatryp[TM] , has shown efficacy in both neuroprotection and cardioprotection, positioning it for a first-inhuman Phase I clinical trial. Nyrada Inc. (ARBN 625 401 818) is incorporated in Delaware, US, with limited liability for its stockholders.

www.nyrada.com

Authorised by Mr. John Moore, Non-Executive Chair on behalf of the Board.

Investors and Media: Company Secretary: Dimitri Burshtein David Franks T: 02 9498 3390 T: 02 8072 1400 E: info@nyrada.com E: david.franks@automicgroup.com.au

Forward-Looking Statements

This announcement may contain forward-looking statements. You can identify these statements by the fact they use words such as “aim”, “anticipate”, “assume”, “believe”, “continue”, “could”, “estimate”, “expect”, “intend”, “may”, “plan”, “predict”, “project”, “plan”, “should”, “target”, “will” or “would” or the negative of such terms or other similar expressions. Forward-looking statements are based on estimates, projections, and assumptions made by Nyrada about circumstances and events that have not yet taken place. Although Nyrada believes the forward-looking statements to be reasonable, they are not certain. Forwardlooking statements involve known and unknown risks, uncertainties and other factors that are in some cases beyond the Company’s control that could cause the actual results, performance, or achievements to differ materially from those expressed or implied by the forward-looking statement.

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Nyrada Inc. Level 3, 828 Pacific Highway, Gordon NSW 2072

ARBN 625 401 818