Nuvalent, Inc. — Director's Dealing 2025

Oct 15, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Nuvalent, Inc. (NUVL)
CIK: 0001861560
Period of Report: 2025-10-13

Reporting Person: Pelish Henry E. (N/A)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-10-13	Class A Common Stock	M	1669	$18.93	Acquired	67632	Direct
2025-10-13	Class A Common Stock	M	4168	$27.85	Acquired	71800	Direct
2025-10-13	Class A Common Stock	M	1800	$72.35	Acquired	73600	Direct
2025-10-13	Class A Common Stock	S	7637	$89.81	Disposed	65963	Direct
2025-10-14	Class A Common Stock	M	731	$18.93	Acquired	66694	Direct
2025-10-14	Class A Common Stock	M	877	$27.85	Acquired	67571	Direct
2025-10-14	Class A Common Stock	M	825	$29.33	Acquired	68396	Direct
2025-10-14	Class A Common Stock	S	1167	$84.98	Disposed	67229	Direct
2025-10-14	Class A Common Stock	S	866	$86.11	Disposed	66363	Direct
2025-10-14	Class A Common Stock	S	400	$87.39	Disposed	65963	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-10-13	Stock Option (Right to Buy)	$18.93	M	1669	Disposed	2032-01-04	Class A Common Stock (1669)	Direct
2025-10-13	Stock Option (Right to Buy)	$27.85	M	4168	Disposed	2033-01-06	Class A Common Stock (4168)	Direct
2025-10-13	Stock Option (Right to Buy)	$72.35	M	1800	Disposed	2034-01-05	Class A Common Stock (1800)	Direct
2025-10-14	Stock Option (Right to Buy)	$18.93	M	731	Disposed	2032-01-04	Class A Common Stock (731)	Direct
2025-10-14	Stock Option (Right to Buy)	$27.85	M	877	Disposed	2033-01-06	Class A Common Stock (877)	Direct
2025-10-14	Stock Option (Right to Buy)	$29.33	M	825	Disposed	2033-03-01	Class A Common Stock (825)	Direct

Footnotes

F1: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 1, 2024.

F2: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $89.80 to $89.83, inclusive. The reporting person undertakes to provide to the staff of the Securities and Exchange Commission, Nuvalent, Inc. or any security holder of Nuvalent, Inc., upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) through (5) of this Form 4.

F3: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $84.64 to $85.63, inclusive.

F4: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $85.89 to $86.81, inclusive.

F5: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $87.33 to $87.56, inclusive.

F6: The shares underlying this option vest as follows: 25% of the shares vested on January 4, 2023, and the remainder have vested or shall vest over the three years thereafter in equal monthly installments, subject to continued service to Nuvalent, Inc. through the applicable vesting date.

F7: The shares underlying this option have vested or shall vest over the four years following January 6, 2023 in equal monthly installments, subject to continued service to Nuvalent, Inc. through the applicable vesting date.

F8: The shares underlying this option have vested or shall vest over the four years following January 5, 2024 in equal monthly installments, subject to continued service to Nuvalent, Inc. through the applicable vesting date.

F9: The shares underlying this option have vested or shall vest over the four years following March 1, 2023 in equal monthly installments, subject to continued service to Nuvalent, Inc. through the applicable vesting date.