Nuvalent, Inc. — Director's Dealing 2025

Nov 19, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Nuvalent, Inc. (NUVL)
CIK: 0001861560
Period of Report: 2025-11-17

Reporting Person: Balcom Alexandra (N/A)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-11-17	Class A Common Stock	M	6875	$6.89	Acquired	68609	Direct
2025-11-17	Class A Common Stock	M	13125	$72.35	Acquired	81734	Direct
2025-11-17	Class A Common Stock	S	3609	$93.80	Disposed	78125	Direct
2025-11-17	Class A Common Stock	S	3266	$95.12	Disposed	74859	Direct
2025-11-17	Class A Common Stock	S	4496	$100.58	Disposed	70363	Direct
2025-11-17	Class A Common Stock	S	3194	$102.13	Disposed	67169	Direct
2025-11-17	Class A Common Stock	S	5055	$103.27	Disposed	62114	Direct
2025-11-17	Class A Common Stock	S	380	$103.68	Disposed	61734	Direct
2025-11-18	Class A Common Stock	M	729	$72.35	Acquired	62463	Direct
2025-11-18	Class A Common Stock	S	220	$103.61	Disposed	62243	Direct
2025-11-18	Class A Common Stock	S	509	$104.54	Disposed	61734	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-11-17	Stock Option (Right to Buy)	$6.89	M	6875	Disposed	2031-04-29	Class A Common Stock (6875)	Direct
2025-11-17	Stock Option (Right to Buy)	$72.35	M	13125	Disposed	2034-01-05	Class A Common Stock (13125)	Direct
2025-11-18	Stock Option (Right to Buy)	$72.35	M	729	Disposed	2034-01-05	Class A Common Stock (729)	Direct

Footnotes

F1: These transactions were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on December 12, 2024.

F2: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $93.73 to $94.38, inclusive. The reporting person undertakes to provide to the staff of the Securities and Exchange Commission, Nuvalent, Inc. or any security holder of Nuvalent, Inc., upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) through (9) of this Form 4.

F3: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $94.93 to $95.58, inclusive.

F4: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $100.11 to $101.07, inclusive.

F5: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $101.57 to $102.47, inclusive.

F6: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $102.60 to $103.54, inclusive.

F7: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $103.65 to $103.79, inclusive.

F8: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $103.14 to $103.96, inclusive.

F9: The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $104.25 to $105.12, inclusive.

F10: The shares underlying this option vest as follows: 25% of the shares vested on April 29, 2022, and the remainder have vested or shall vest over the three years thereafter in equal monthly installments, subject to continued service to Nuvalent, Inc. through the applicable vesting date.

F11: The shares underlying this option have vested or shall vest over the four years following January 5, 2024 in equal monthly installments, subject to continued service to Nuvalent, Inc. through the applicable vesting date.