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NUFORMIX PLC

Earnings Release Dec 20, 2018

4941_ir_2018-12-20_b3200d65-c906-4f69-94de-a1d4c20a22a0.html

Earnings Release

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RNS Number : 0483L

Nuformix PLC

20 December 2018

Nuformix plc

("Nuformix" or "the Company"),

Unaudited Half Year Results

for the six months ended 30 September 2018

Significant Progress in Lead Programmes

Cambridge, UK, 20th December 2018: Nuformix (LSE: NFX), the pharmaceutical development company using cocrystal technology to unlock the therapeutic potential of approved small molecule drugs, announces the Company's unaudited results for the six months ended 30 September 2018.

KEY HIGHLIGHTS

·      Pipeline Update:

·      Key development milestone achieved for NXP001 in Oncology Supportive Care triggering payment of £500,000

·      Additional patent filing broadening NXP002 applications in fibrotic conditions

·      Continued growth of pre-clinical portfolio following the development of new drug cocrystals

·      Strengthening Board:

·      Dr Chris Blackwell appointed to the Nuformix Board as a Non-Executive Director

·      Financial Highlights:

·      Reported net loss for the period was £642,633 (2017: £127,546 loss)

·      Operating profit before exceptional items for the reported period was positive at £114,020 (2017: £170,725 loss)

POST PERIOD HIGHLIGHTS

·      Key milestone achieved for NXP002 programme in treating fibrosis:

·        Preclinical multi-patient tissue studies were completed in partnership with Newcastle University, UK in Q4 2018

·        Resulting data demonstrated NXP002 candidates strongly inhibit fibrosis ex-vivo, even in very severely fibrotic human lung tissue taken from patients at end stage with idiopathic lung fibrosis (IPF)

·      In addition, a very specific action was observed against key inflammatory targets

Commenting on the outlook, Dr Dan Gooding, CEO, Nuformix plc said: "We have achieved significant progress during the period, both operationally and within our lead programmes. The results strongly validate the Company's strategy of combining a 'lean burn' model and low operational costs with early revenues from both out-licensing and collaborative development. We have continued to progress our two lead programmes during the second half of 2018, reaching significant milestones for our oncology drug NXP001 and our fibrosis drug NXP002. We can look forward to achieving further clinical and commercial progress for both programmes in the first half of 2019 whilst maintaining low operating costs."

The information contained within this announcement is deemed to constitute inside information as stipulated under the Market Abuse Regulation (EU) No. 596/2014. Upon the publication of this announcement, this inside information is now considered to be in the public domain.

Enquiries:

Nuformix plc

Dr Dan Gooding, Chief Executive Officer
+44 (0)1223 423667
Optimum Strategic Communications

Supriya Mathur, Mary Clark

Email: [email protected]
+44 (0) 203 950 9144

About Nuformix plc  

Nuformix is a pharmaceutical development company using cocrystal technology to unlock the therapeutic potential of approved small molecule drugs. Nuformix's risk-mitigated development strategy has resulted in a pipeline of discoveries through which it has developed and patented novel cocrystal forms of approved small molecules.

Nuformix has created an IP portfolio of granted patents covering cocrystal forms of five small molecule drugs.  Nuformix is targeting high-value unmet needs with its lead programmes in:

·      NXP001: Oncology supportive care

·      NXP002: Treating fibrosis

Nuformix was established in Cambridge in 2009 and has invested in pharmaceutical cocrystal R&D, establishing world-class capability and know-how in cocrystal discovery and development, yielding multiple product opportunities. 

Nuformix plc shares are traded on the London Stock Exchange's Official List under the ticker: NFX.L.

For further information, please visit www.nuformix.com.

Half Year Report

The Company is pleased to update shareholders regarding the Company's developments during the first half of the year ending 30 September 2018 and subsequent events to date in the second half.

Half Year Overview

The Company conducts pharmaceutical development activities, minimising risk in clinical development by creating innovative new therapies based on known drugs with proven safety. The Company's innovative therapies are made possible via cocrystal technology, which provides new intellectual property (IP) plus performance and commercial advantages to enable the development of new products.

Nuformix seeks to maximise the value of its existing IP portfolio by conducting clinical proof-of-concept studies for a small number of compelling assets prior to generating revenues from out-licensing.

The Company has achieved significant progress during the period, both operationally and within its lead programmes. The results strongly validate the Company's strategy of combining a 'lean burn' model and low operational costs with early revenues from both out-licensing and collaborative development.

As a result, the Company is able to report an operating profit before exceptional items for the period of £114,020 (2017: £170,657 loss). The net results for the period are impacted by share option charges, which are not cash reducing, of £765,667. Overall, the reported net loss for the period is £642,633 (2017: £127,546 loss).

Earlier this year the Company completed a full strategic review of the Nuformix lead programmes, NXP001 in oncology supportive care and NXP002 in the treatment of fibrosis and included both commercial and operational aspects. The review also looked at the Company's broader portfolio, including early-stage pipeline and potential additional projects. The review provided the Board and the Advisory Panel with a refreshed perspective on the overall commercial and development potential across the pipeline and the associated objectives for each work stream.

As a result of the strategic review, the management team identified development targets for its two lead programmes opportunities and has made significant progress during the year as follows:

NXP001 Programme: Oncology Supportive Care

·      On track to deliver its first human pharmacokinetic data in H1 2019

·      MHRA clearance expected in February 2019 and patients scheduled for dosing in March 2019

·      All clinical materials generated and ready for study commencement

·      Demonstration of bioequivalence to the reference product will trigger a £2 million milestone payment

·      First milestone was achieved and the first NSB payment of £500,000 was received in Q4 2018

·      In November, announced an expanded licensing agreement with NSB for the China market

·      Rest of the World discussions for NXP001 commenced

Following the expanded agreement announced in November with NSB, Nuformix will be carrying out an additional pre-clinical study for NXP001 in parallel to its on-going clinical studies, to further validate additional differentiated product opportunities. Completion of the additional study will result in a milestone payment of £500,000 from NSB.

Total milestone payments from NSB will therefore increase from £2.5 million to £3 million, following the addition of this second pre-clinical milestone, which Nuformix expects to achieve in Q1 2019. The resulting data will support regulatory submissions in China to facilitate market approval of multiple NXP001-derived products.

NXP002 Programme: Treating Fibrosis

·      Preclinical multi-patient tissue studies were conducted in partnership with Newcastle University, UK

·     Resulting data demonstrated NXP002 candidates strongly inhibit fibrosis ex-vivo, even in very severely fibrotic human lung tissue taken from patients at end stage with IPF
·      In addition, a very specific action was observed against key inflammatory targets
·      NXP002 candidates out-performed current treatment standard of care (Pirfenidone, Esbriet ®)
·      Leading edge human tissue trial model closely replicates real-life patient disease
·     First results of their kind to be released in partnership with Newcastle University, UK. Positive trial results achieved against a high challenging model (end-stage patients)
·      These data provide strong support for wider applications in other fibrotic lung conditions
·      Additional patent filing made to broaden NXP002 applications in fibrotic conditions

The Company is highly encouraged by the first results from its partnership with Newcastle University (UK) and using cutting-edge human tissue disease models, Nuformix has demonstrated the potential for NXP002 candidates to attenuate progression in established lung fibrosis.

Life expectancy has not changed for patients diagnosed with IPF. Few patients respond to the two currently approved treatments and have to tolerate severe side effects that dramatically impact quality of life - severe vomiting on one therapy or severe diarrhoea on the other. The promising data from the NXP002 study gives us confidence in its ability to both inhibit fibrosis and address inflammation in patients without these side effects.

Nuformix announced in September an additional patent filing, which provides further strength and breadth to the existing NXP002 patent portfolio. The additional patent filing allows Nuformix to consider a wider range of options in the treatment of fibrosis, delivering wider benefit for patients whilst maximising value for investors.

Fibrotic disease is typically associated with high patient mortality, increasing prevalence and a lack of safe and effective treatments. Whilst, fibrosis treatments are in their infancy the emerging lung fibrosis market demonstrates their blockbuster potential. Markets for other fibrotic conditions are under-developed, with large and growing patient populations (e.g. the global liver disease market is predicted to reach $12.1 billion by 2022).

Strategy

The Company is focussed on building value for shareholders through its activities in drug development and out-licensing. Nuformix uses cocrystal technology to re-engineer the crystalline form of known small molecule drugs. The resulting novel drug cocrystals have new and improved physical properties that can enable advantageous new products, in addition to strategic benefits. Furthermore, the resulting drug cocrystals are protected with new 'substance of matter' IP protection.

Nuformix's cocrystal technology expertise generates value and revenue by developing new cocrystal-based therapies using known drugs and licensing them to pharmaceutical companies post proof-of-concept. The initial product development focus is in the fields of oncology supportive care and fibrosis. However, the Company is building a pipeline of additional products behind its lead programmes, which it will continue to develop both in-house and in collaboration with external partners.

Strengthening Company Board

During the period, the Company has strengthened the Board of Directors with Dr Chris Blackwell's appointment to the Nuformix Board as a Non-Executive Director. His addition brings a wealth of proven expertise in life sciences value creation and broadens the Company's network.

Outlook

The Company will continue to progress its two lead programmes during the second half of the financial year ending 31st March 2019, with the commencement of clinical studies during Q1 of the calendar year for its NXP001 programme in oncology supportive care, which is on track to achieve significant development and commercial milestones during the period.

The Company will also continue to execute its commercial strategy as it seeks to out-license Rest of World marketing rights for NXP001, in addition to entering new collaborative development partnerships.

In fibrosis, the Company will seek to optimise delivery of candidates within its NXP002 programme, focussing on the treatment of unmet needs within idiopathic fibrosis.

In addition, the Company will continue to execute its product development strategy of using cocrystal technology to enable the redevelopment of small molecule drugs with therapeutic promise, adding value to its IP portfolio and pipeline, whilst maintaining low operating costs.

Dr Dan Gooding, CEO

20 December 2018
Dr David Tapolczay, Chairman

The information contained within this announcement is deemed to constitute inside information as stipulated under the Market Abuse Regulation (EU) No. 596/2014. Upon the publication of this announcement, this inside information is now considered to be in the public domain.

Nuformix plc

(Registration number: 09632100)

Unaudited Interim Results

Consolidated Income Statement and Statement of Comprehensive Income for the

Half Year Ended 30 September 2018

Note 30 September

2018

Unaudited

£
30 September

2017

Unaudited

£
31 March

2018

Audited

£
Revenue 610,000 5,000 15,000
Cost of sales (79,433) (12,682) (203,868)
Gross profit/(loss) 530,567 (7,682) (188,868)
Administrative expenses before exceptional items (419,410) (170,725) (729,016)
Exceptional Items 4 (765,667) - (1,062,142)
Total administrative expenses (1,185,077) (170,725) (1,791,158)
Other operating income 2,863 7,750 18,520
Operating profit/(loss) before exceptional items 114,020 (170,657) (899,364)
Operating loss after exceptional items (651,647) (170,657) (1,961,506)
Finance (costs)/income (10,986) 7,384 (3,547)
Loss before tax (662,633) (163,273) (1,965,053)
Income tax receipt 20,000 35,727 126,790
Loss for the year and total comprehensive income for the period (642,633) (127,546) (1,838,263)
Loss per share - basic and diluted 5 (0.14)p (127.5)p (0.49)p

Nuformix plc

(Registration number: 09632100)

Unaudited Interim Results

Consolidated Statement of Financial Position as at 30 September 2018 

Note 30 September

2018

Unaudited

£
30 September

2017

Unaudited

£
31 March

2018

Audited

£
Assets
Non-current assets
Property, plant and equipment 6 32,904 10,014 37,494
Intangible assets 7 4,272,257 247,487 4,275,920
4,305,161 257,501 4,313,414
Current assets
Trade and other receivables 702,640 27,605 180,322
Income tax asset 146,796 103,072 195,236
Cash and cash equivalents 32,660 - 338,167
882,096 130,677 713,725
Total assets 5,187,257 388,178 5,027,139
Equity and liabilities
Equity
Share capital 8 460,750 100 460,750
Share premium 2,932,590 509,965 2,932,590
Merger relief reserve 10,950,000 - 10,950,000
Reverse acquisition reserve (8,005,195) - (8,005,195)
Share option reserve 1,490,504 - 724,837
Retained earnings (3,212,473) (859,122) (2,569,840)
Total equity 4,616,176 (349,057) 4,493,142
Current liabilities
Trade and other payables 530,394 493,033 511,041
Loans and borrowings 40,687 204,600 22,956
Bank overdraft - 39,602 -
571,081 737,235 533,997
Total equity and liabilities 5,187,257 388,178 5,027,139

Nuformix plc

(Registration number: 09632100)

Unaudited Interim Results

Consolidated Statement of Changes in Equity for the Half Year Ended 30 September 2018 - Unaudited

Share capital

£
Share premium

£
Merger Relief Reserve

£
Reverse acquisition reserve

£
Share option reserve Retained earnings

£
Total

£
At 31 March 2017 100 509,965 - - - (731,576) (221,511)
Loss for the half year - - - - - (127,546) (127,546)
At 30 September 2017 100 509,965 - - - (859,122) (349,057)
Arising on reverse acquisition 95,650 227,475 - (345,820) 22,695 - -
Loss for the half year and total comprehensive loss - - - - - (1,710,718) (1,710,718)
Issue of shares as consideration 300,000 - 10,950,000 - - - 11,250,000
Share issue costs - (339,850) - - - - (339,850)
Arising on reverse acquisition - - - (7,659,375) - - (7,659,375)
Issue of share capital 57,500 2,242,500 - - - - 2,300,000
Share based payment 7,500 292,500 - - 702,142 - 1,002,142
At 31 March 2018 460,750 2,932,590 10,950,000 (8,005,195) 724,837 (2,569,840) 4,493,142
Loss for the half year - - - - - (642,633) (642,633)
Share Based Payment - - - - 765,667 - 765,667
As at 30 September 2018 460,750 2,932,590 10,950,000 (8,005,195) 1,490,504 (3,212,473) 4,616,176

Nuformix plc

(Registration number: 09632100)

Unaudited Interim Results

Consolidated Statement of Cash Flows for the Half Year Ended 30 September 2018

Note 30 September

2018

Unaudited

£
30 September 2017

Unaudited

£
31 March

2018

Audited

£
Cash flows from operating activities
Loss for the year (642,633) (127,546) (1,838,263)
Adjustments to cash flows from non-cash items
Depreciation and amortisation 26,376 18,372 47,433
Finance (costs)/ income (10,986) (7,384) 3,547
Income tax expense (20,000) (35,727) (126,790)
Share based payment and acquisition costs 765,667 - 1,002,142
118,425 (152,285) (911,992)
Working capital adjustments
Increase in trade and other receivables 360,650 66,819 80,434
Increase in trade and other payables (785,020) 34,034 (631,321)
Cash generated from operations (305,945) (51,432) (1,462,819)
Income taxes (paid)/received - - (68,445)
Net cash flow from operating activities (305,945) (51,432) (1,531,264)
Cash flows from investing activities
Cash acquired on reverse acquisition - - 678
Acquisitions of property plant and equipment - - (44,094)
Acquisition of intangible assets - - (57,202)
Net cash flows from investing activities (305,945) (51,432) (100,618)
Cash flows from financing activities
Proceeds of share issue - - 1,960,150
Interest paid (774) (717) (2,061)
Foreign exchange (gains) / losses 1,212 8,101 7,514
Net cash flows from financing activities 438 7,384 1,965,603
Net increase in cash and cash equivalents (305,507) (44,048) 333,721
Cash and cash equivalents at start of period 338,167 4,446 4,446
Cash and cash equivalents at end of period 32,660 (39,602) 338,167

Nuformix plc

(Registration number: 09632100)

Unaudited Interim Results

Notes to the Consolidated Financial Statements for the Half Year Ended

30 September 2018

1 Basis of preparation of interim financial information

The consolidated interim financial statements have been prepared in accordance with the recognition and measurement principles of International Financial Reporting Standards as endorsed by the European Union ("IFRS") and expected to be effective at the year-end of 31 March 2018.

Accounting policies remain unchanged from the financial statements for the year ended 31 March 2018.

The interim financial statements are unaudited and do not constitute statutory accounts within the meaning of Section 434 of the Companies Act 2006. Statutory accounts for the year ended 31 March 2018, prepared in accordance with IFRS, have been filed with the Registrar of Companies.  The Auditors' Report on these accounts was unqualified, did not include any matters to which the Auditors drew attention by way of emphasis without qualifying their report and did not contain any statements under section 498 of the Companies Act 2006.

The consolidated interim financial statements are for the 6 months to 30 September 2018.

The interim consolidated financial information do not include all the information and disclosures required in the annual financial statements, and should be read in conjunction with the group's annual financial statements for the year ended 31 March 2018, which were prepared in accordance with IFRS's as adopted by the European Union.

2 Basis of consolidation

On 16 October 2017 the Company acquired the entire issued ordinary share capital of Nuformix Technologies Limited and became the legal parent of Nuformix Technologies Limited. The accounting policy adopted by the Directors applies the principles of IFRS 3 (Revised) "Business Combinations" in identifying the accounting parent as Nuformix Technologies Limited and the presentation of the Group consolidated statements of the Company (the legal parent) as a continuation of financial statements of the accounting parent or legal subsidiary (Nuformix Technologies Limited).

The interim consolidated financial statements cover the six months ended 30 September 2018.  The interim financial statements for the comparative period ended 30 September 2017 represent the substance of the reverse acquisition and are those of Nuformix Technologies Limited.

3 Going concern

The financial statements have been prepared on the going concern basis of preparation which, inter alia, is based on the directors' reasonable expectation that the Group has adequate resources to continue to operate as a going concern for at least twelve months from the date of their approval.  In forming this assessment, the directors have prepared cashflow forecasts covering the period ending 30 November 2019 which take into account the likely run rate on overheads and research expenditure and the prudent expectations of income from its lead programmes.

Whilst there can be no guarantee of the successful outcome of future trials, in compiling the cashflow forecasts the directors have made cautious estimates of the likely outcome of such trials, when income might be generated and have considered alternative strategies should projected income be delayed or fails to materialise.  These strategies include postponing non-committed research expenditure, securing alternative licensing arrangements from those currently planned and using the Group's established network of licensed brokers for fundraising. 

After careful consideration, the directors consider that they have reasonable grounds to believe that the Group can be regarded as a going concern and, for this reason, they continue to adopt the going concern basis in preparing the Group's financial statements.

4 Exceptional Item

As part of the reverse acquisition the Group issued a number of options and warrants to existing directors, new directors and for the provision of professional services in relation to the successful completion of the transaction and in respect of the new directors' future service. Details of the share based payments can be found in note 9.

30 September

2018

Unaudited



£
30 September

2017

Unaudited

£
31 March

2018

Audited



£
Share option charge 765,667 - 702,142
Acquisition costs - - 360,000
765,667 - 1,062,142

5 Loss per Share

Loss per share is calculated by dividing the loss after tax attributable to the equity holders of the Group by the weighted average number of shares in issue during the year. As no new shares were issued during the time period, the weighted average is the same as the total shares as at the start of the year.

The basic earnings per share for each comparative period shall be calculated by dividing the profit of the legal entity in each of those period by the legal entities historical weighted average number of shares outstanding multiplied by the exchange ratio.

30 September

2018

Unaudited

£
30 September

2017

Unaudited

£
31 March

2018

Audited

£
Loss before tax (642,633) (127,546) (1,838,263)
Weighted average number of shares - basic and diluted 460,750,000 1,000 373,548,630
Basic and diluted loss per share (0.14)p (127.5)p (0.49)p

6 Property, Plant and Equipment

Leasehold improvements

£
Computer equipment

£
Lab equipment

£
Total

£
Cost or valuation
At 31 March 2017 - 12,858 7,568 20,426
Additions 14,650 750 - 15,400
Disposals - (250) - (250)
At 30 September 2017 14,650 13,358 7,568 35,576
Additions 17,554 9,949 1,194 28,697
Disposals (5,959) - (5,959)
At 31 March 2018 32,204 17,348 8,762 58,314
Additions - - 966 966
Disposals - - - -
At 30 September 2018 32,204 17,348 9,732 59,280
Depreciation
At 31 March 2017 - 11,971 6,722 18,693
Charge 5,367 1,213 539 7,119
Eliminated on disposal - (250) - (250)
At 30 September 2017 5,367 12,934 7,261 25,562
Charge - 1,214 - 1,214
Eliminated on disposal - (5,959) - (5,959)
At 31 March 2018 5,367 8,189 7,261 20,817
Charge 3,220 1,930 409 5,559
Eliminated on disposal - - - -
At 30 September 2018 8,587 10,119 7,670 26,376
Carrying amount
At 30 September 2017 9,283 424 307 10,014
At 31 March 2018 26,837 9,159 1,501 37,497
At 30 September 2018 23,617 7,229 2,062 32,904

7 Intangible Assets

Goodwill

£
Patents

£
Total

£
Cost
At 31 March 2017 - 333,791 333,791
Additions - 30,727 30,727
At 30 September 2017 364,518 364,518
Additions 4,023,484 26,474 4,049,958
At 31 March 2018 4,023,484 390,993 4,414,476
Additions - 16,448 16,448
At 30 September 2018 4,023,484 407,440 4,430,924
Amortisation
At 31 March 2017 - 99,457 99,457
Amortisation charge - 17,574 17,574
At 30 September 2017 - 117,031 117,031
Amortisation charge - 21,525 21,525
At 31 March 2018 - 138,556 138,556
Amortisation charge - 20,111 20,111
At 30 September 2018 - 158,667 158,667
Net book value
At 30 September 2017 - 247,487 247,487
At 31 March 2018 4,023,484 252,436 4,275,920
At 30 September 2018 4,023,484 248,773 4,272,257

For impairment testing purposes, management consider the operations of the Group to represent a single CGU focused on the research and development. Consequently, the goodwill is effectively allocated and considered for impairment against the business as a whole being the single CGU.

8 Share Capital

Allotted, called up and fully paid shares

30 September

2018

Unaudited
30 September

2017

Unaudited
31 March 2018

Audited
No. £ No. £ No. £
Ordinary shares of £0.001 each

(Sep 17: £0.10)
460,750,000 460,750 1,000 100 460,750,000 460,750

9 Share Options

The Group operates share-based payments arrangements to remunerate directors and key employees in the form of a share option scheme. Equity-based share-based payments are measured at fair value (excluding the effect of non-market based vesting conditions) at the date of grant. The fair value is determined at the grant date of the equity-settled share-based payments is expensed on a straight line basis over the vesting period, based on the Group's estimate of shares that will eventually vest and adjusted for the effect of non-market based vesting conditions.

As part of the reverse acquisition of Nuformix Technologies Limited the following share-based payments were made in the half year:

·    79,650,050 unapproved share options were issued on 16 October 2017. The options have a 1 year vesting period, an exercise price of 4p per share and a 4 year exercise period from vesting. The fair value of the options was determined as 1.7p per share and a charge of £638,946 has been recognised in the current period.

·    12,499,950 options under an EMI share options scheme were issued on 16 October 2017. The options have a 1 year vesting period, an exercise price of 4p per share and a 4 year exercise period from vesting. The fair value of the options was determined as 1.6p per share and a charge of £106,541 has been recognised in the current period.

·   1,625,000 Existing director warrants were issued on 15 September 2017. The warrants have a 1 year vesting period, an exercise price of 4p per share and a 2 year exercise period from vesting. The fair value of the warrants was determined as 1.4p per share and a charge of £11,406 has been recognised in the current period.

·   1,250,000 Shakespeare Martineau warrants were issued on 15 September 2017. The warrants have a 1 year vesting period, an exercise price of 4p per share and a 2 year exercise period from vesting. The fair value of the options was determined as 1.4p per share and a charge of £8,774 has been recognised in the current period.

The fair value of the options and warrants was determined using the Black-Scholes option pricing model and was an average of 1.61p per option (2017: 1.25p per option). The significant inputs into the model in respect of the options and warrants granted in the year ended 31 March 2018 were as follows:

2018 2018 2018 2018 2017
Unapproved options EMI options Existing director warrants Shakespeare Martineau warrants Howard Whitman warrants
Grant date share price 4p 4p 4p 4p 4p
Exercise price 4p 4p 4p 4p 4p
No. of share options 79,650,050 12,499,950 1,625,000 1,250,000 250,000
Risk free rate 0.5% 0.5% 0.5% 0.5% 0.5%
Expected volatility 50% 50% 50% 50% 50%
Expected option life 5 years 5 years 3 years 3 years 2 years

Statement of Directors Responsibilities

We confirm that to the best of our knowledge:

1.   the interim condensed set of financial statements has been prepared in accordance with IAS 34 'Interim Financial Reporting' as issued by the IASB and adopted by the EU;

2.   the interim management report includes a fair review of the information required by:

2.1.  DTR 4.2.7R of the Disclosure Guidance and Transparency Rules, being an indication of important events that have occurred during the first six months of the financial year and their impact on the condensed set of financial statements; and a description of the principal risks and uncertainties for the remaining six months of the year; and

2.2.  DTR 4.2.8R of the Disclosure Guidance and Transparency Rules, being related party transactions that have taken place in the first six months of the current financial year and that have materially affected the financial position or performance of the entity during that period; and any changes in the related party transactions described in the last annual report that could do so.

The directors of Nuformix PLC are listed in the Group's 2018 Annual Report and Accounts.

D Gooding

Chief Executive

Further copies of this document are available from the company's registered address and will be available on the company's website later today.

Nuformix plc

(Registration number: 09632100)

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact [email protected] or visit www.rns.com.

END

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