Nevis Brands Inc. — Board/Management Information 2021

Sep 7, 2021

Form 51-102F3 Material Change Report

PART 2 CONTENT OF MATERIAL CHANGE REPORT

Item 1 Name and Address of Company PASCAL BIOSCIENCES INC. 4000 Mason Road, Suite 304 Seattle WA 98195 Item 2 D ate of Material Change September 7, 2021 Item 3 News Release September 7, 2021 Filed with the TSX.V, Sedar and Stockwatch Item 4 Summary of Material Change The Company has changed its CEO and President. Item 5 Full Description of Material Change Effective September 3, 2021, Rob Geitl of West Vancouver, B.C. was appointed CEO and President to replace Patrick Gray as CEO and Mark van der Horst as President. Patrick Gray was appointed executive chairman of the board of directors. Item 6 Reliance on subsection 7.1(2) or (3) of National Instrument 51-102 N/A Item 7 Omitted Information No information has been omitted on the basis that it is confidential information. Item 8 Executive Officer Rob Geitl – CEO, President Telephone: 604 8494111 Email: robgietl@gmail.com

I tem 9 Date of Report September 7, 2021

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