Natera, Inc. — Director's Dealing 2025

Oct 25, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Natera, Inc. (NTRA)
CIK: 0001604821
Period of Report: 2025-10-22

Reporting Person: Brophy Michael Burkes (N/A)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-10-22	Common Stock	S	920	$186.68	Disposed	69189	Direct
2025-10-22	Common Stock	M	1250	—	Acquired	70439	Direct
2025-10-23	Common Stock	S	495	$187.16	Disposed	69944	Direct
2025-10-24	Common Stock	S	755	$196.77	Disposed	69189	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-10-22	Restricted Stock Unit	$	M	1250	Disposed		Common Stock (1250)	Direct

Footnotes

F1: The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 14, 2024.

F2: Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of the Issuer's Common Stock.

F3: The sale of shares was effected in order to satisfy tax withholding and remittance obligations in connection with the vesting of RSUs and made pursuant to a written instruction that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) under the Exchange Act contained in the Reporting Person's Stock Unit Agreement granted on October 22, 2021.

F4: The RSUs vest over four years. 25% of the RSUs vested on October 22, 2022 and the remaining shares vest in 12 equal quarterly installments thereafter.