Natera, Inc. — Director's Dealing 2025

Nov 26, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Natera, Inc. (NTRA)
CIK: 0001604821
Period of Report: 2025-11-24

Reporting Person: BOTHA ROELOF (Director)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-11-24	Common Stock	S	2000	$228.9672	Disposed	1227198	Indirect
2025-11-24	Common Stock	S	1000	$230.0300	Disposed	1226198	Indirect
2025-11-24	Common Stock	S	900	$231.2335	Disposed	1225298	Indirect
2025-11-24	Common Stock	S	3606	$232.7533	Disposed	1221692	Indirect
2025-11-24	Common Stock	S	7032	$233.6601	Disposed	1214660	Indirect
2025-11-24	Common Stock	S	9991	$234.5512	Disposed	1204669	Indirect
2025-11-24	Common Stock	S	9623	$235.6512	Disposed	1195046	Indirect
2025-11-24	Common Stock	S	6173	$236.5380	Disposed	1188873	Indirect
2025-11-24	Common Stock	S	15336	$237.6930	Disposed	1173537	Indirect
2025-11-24	Common Stock	S	18839	$238.5699	Disposed	1154698	Indirect
2025-11-24	Common Stock	S	500	$239.1100	Disposed	1154198	Indirect

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	2428	Direct

Footnotes

F1: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $228.70 to $229.63. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff at the Securities and Exchange Commission, upon request, the full information regarding the number of shares sold at each separate price within the ranges set forth above.

F2: Includes 4,411 shares transferred to an estate planning vehicle in a transaction exempt from Section 16 pursuant to Rule 16a-13.

F3: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $230.00 to $230.05. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff at the Securities and Exchange Commission, upon request, the full information regarding the number of shares sold at each separate price within the ranges set forth above.

F4: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $231.04 to $231.83. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff at the Securities and Exchange Commission, upon request, the full information regarding the number of shares sold at each separate price within the ranges set forth above.

F5: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $232.09 to $233.08. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff at the Securities and Exchange Commission, upon request, the full information regarding the number of shares sold at each separate price within the ranges set forth above.

F6: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $233.09 to $234.08. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff at the Securities and Exchange Commission, upon request, the full information regarding the number of shares sold at each separate price within the ranges set forth above.

F7: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $234.09 to $235.08. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff at the Securities and Exchange Commission, upon request, the full information regarding the number of shares sold at each separate price within the ranges set forth above.

F8: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $235.09 to $236.08. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff at the Securities and Exchange Commission, upon request, the full information regarding the number of shares sold at each separate price within the ranges set forth above.

F9: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $236.09 to $237.08. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff at the Securities and Exchange Commission, upon request, the full information regarding the number of shares sold at each separate price within the ranges set forth above.

F10: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $237.09 to $238.08. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff at the Securities and Exchange Commission, upon request, the full information regarding the number of shares sold at each separate price within the ranges set forth above.

F11: The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $238.09 to $239.07. The Reporting Person undertakes to provide the Issuer, any security holder of the Issuer, or the staff at the Securities and Exchange Commission, upon request, the full information regarding the number of shares sold at each separate price within the ranges set forth above.