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MorphoSys AG — Investor Presentation 2012
Mar 2, 2012
291_ip_2012-03-02_c8c03d92-b8cf-4aed-a414-53dd5591e7a3.pdf
Investor Presentation
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Year End Results 2011 & Outlook
Safe Harbour
This presentation includes forward-looking statements.
Actual results could differ materially from those included in the forward-looking statements due to various risk factors and uncertainties including changes in business, economic competitive conditions, regulatory reforms, foreign exchange rate fluctuations and the availability of financing.
These and other risks and uncertainties are detailed in the Company's Annual Report.
Contents
- Review 2011
- Pipeline
- Technology
- AbD Serotec
- Financials
- Financial Outlook 2012
- Operational Outlook 2012
- Pipeline
- Technology
- AbD Serotec
Pipeline
MorphoSys Pipeline Continues to Grow & Mature
Clinical Pipeline Increased by Three Programs
Number of clinical development programs in our pipeline
MorphoSys's Proprietary Programs in Clinical Trials (I)
Data in Q3 2012
Data in 2013
GM-CSF: A Novel Target Gaining Importance in RA & MS
Mavrilimumab program provides clinical validation of pathway
Two independent studies confirm view of GM-CSF as key cytokine in MS
MorphoSys's Proprietary Programs in Clinical Trials (II)
Progress in Early Programs
1 program
1 program
Clinical Antibody Pipeline
| Program | Partner | Indication | Discovery | Pre-clinic | Phase 1 | Phase 2 |
|---|---|---|---|---|---|---|
| MOR103 (2 programs) | own | Rheumatoid arthritis, Multiple sclerosis |
||||
| not disclosed |
Novartis | not disclosed |
||||
| CNTO888 (2 programs) | Janssen/J&J | Cancer IPF |
||||
| Gantenerumab | Roche | Alzheimer's Disease | ||||
| BHQ880 | Novartis | Cancer | ||||
| BYM338 | Novartis | Musculoskeletal | ||||
| CNTO 1959 | Janssen/J&J | Psoriasis | ||||
| not disclosed |
Novartis | Ophthalmology | New! | |||
| MOR202 | own | Cancer | ||||
| MOR208 | own | Cancer | ||||
| CNTO 3157 | Janssen/J&J | Asthma | ||||
| not disclosed |
Janssen/J&J | Inflammation | ||||
| not disclosed |
Novartis | Inflammation | ||||
| not disclosed |
Boehringer Ingelheim | Cancer | ||||
| not disclosed |
Pfizer | Cancer | ||||
| OMP-59R5 | Oncomed | Cancer | ||||
| OMP-18R5 | Oncomed | Cancer | ||||
| BAY94-9343 (ADC) | Bayer HealthCare | Cancer |
Progress in 2011 Progress in 2012 Not shown: 24 in pre-clinic
32 in discovery
Gantenerumab: First Clinical Data Supports Approach in AD
- First imaging data confirms Aβ plaque clearance
- 360 patients in Phase 2 trial in 100 centers in 19 countries
-
Roche focuses on early Alzheimer's disease intervention
-
Bapineuzumab and solanezumab data
- Gantenerumab and bapineuzumab in independent trial
Technology
MorphoSys's Next Generation Platform Ylanthia
AbD Serotec
Growing Focus on Diagnostics
First diagnostic HuCAL-based kits entered the market
Diagnostic HuCAL Products
| Disease | Partner | Antibody Generation | Development | Regulatory Approval | Market |
|---|---|---|---|---|---|
| Autoimmune | Phadia | ||||
| Autoimmune Disease | Proteomika | ||||
| Rheumatoid Arthritis |
Proteomika | ||||
| Rheumatoid Arthritis |
Proteomika | ||||
| Cancer | Proteomika | ||||
| Maternal Healthcare | n.d. | ||||
| Immune Suppression |
n.d. | ||||
| Diabetes | n.d. | ||||
| Infectious Disease | n.d. | ||||
| Malaria | FIND | ||||
| Cardiac | n.d. | ||||
| Cancer | n.d. |
Slonomics – New Opportunities for AbD Serotec in Industrial Biotechnology Applications
Financials
Double-digit Growth in Key Financials
FY2011: Income Statement
| in € million |
2011 | 2010 | Change |
|---|---|---|---|
| Revenues | 100.8 | 87.0 | +16% |
| Cost of Goods Sold | 7.0 | 7.3 | |
| Total Research and Development Expenses | 57.5 | 46.9 | |
| Sales, General & Administrative Expenses | 24.6 | 23.2 | |
| Total Operating Expenses | 89.1 | 77.4 | +15% |
| Other Operating Income | 0.5 | 0.2 | |
| Profit from Operations | 12.2 | 9.8 | +24% |
| Finance Income | 1.4 | 4.1 | |
| Other Expenses | 2.1 | 0.8 | |
| Profit before Taxes | 11.4 | 13.2 | -14% |
| Income Tax Expenses | 3.2 | 4.0 | |
| Net Profit | 8.2 | 9.2 | -11% |
| EPS (diluted) | 0.36 | 0.40 |
Composition of Group Revenues
- Success-based Payments
- Proprietary Development
- License Fees and R&D Funding
- AbD Serotec
Five-Year Overview: Solid Financial Situation
Substantial Investment Into Proprietary R&D
in € million
Split of MorphoSys's investment in proprietary development in 2011
Other Expenses
FY2011: Balance Sheet
| in € million |
2011 | 2010 | |
|---|---|---|---|
| Assets | |||
| Cash, Cash Equivalents & Marketable Securities |
134.4 | 108.4 | |
| Other Current Assets | 20.3 | 24.1 | |
| Total Non-Current Assets | 73.7 | 77.3 | |
| Total Assets | 228.4 | 209.8 | |
| Liabilities & Stockholders' Equity | |||
| Total Current Liabilities | 23.8 | 21.4 | |
| Total Non-Current Liabilities | 7.5 | 2.5 | |
| Total Stockholders' Equity | 197.1 | 185.9 | |
| Total Liabilities & Stockholders' Equity | 228.4 | 209.8 |
MorphoSys's Shareholder Base
Guidance 2012
| in € million |
2012 | 2011 |
|---|---|---|
| Group Revenues | 75 – 80 |
100.8 |
| Investment into Proprietary R&D | 20 – 25 |
36.7 |
| Group EBIT | 1 – 5 |
11.1 |
| in € million |
2012 | 2011 |
|---|---|---|
| AbD Serotec Segment Revenues (at constant currency) |
20 – 22 |
19.3 |
| AbD Serotec EBIT Margin (at constant currency) |
~ 6% – 8% |
5% |
How to Look at MorphoSys?
Outlook 2012
Outlook 2012
Own Clinical Programs to Advance Significantly in 2012
The Partnered Pipeline What's Coming Up?
Expected dates for completion of clinical trials (MorphoSys estimates)
Visibility on Pipeline Value Increases Constantly
Outlook 2012
Other Items to Watch Out For
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