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MORGAN STANLEY Capital/Financing Update 2021

Aug 11, 2021

29766_prs_2021-08-11_bcfa3abf-4a2c-43bb-bf9f-17a16bebaf46.zip

Capital/Financing Update

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CALCULATION OF REGISTRATION FEE

Title of Each Class of Securities Offered Maximum Aggregate Offering Price Amount of Registration Fee
Trigger Performance Leveraged Upside Securities due 2026 $336,000 $36.66

August 2021

Pricing Supplement No. 2,087 Registration Statement Nos. 333-250103; 333-250103-01 Dated August 9, 2021 Filed pursuant to Rule 424(b)(2)

M organ S tanley F inance LLC

STRUCTURED INVESTMENTS

Opportunities in U.S. Equities

Trigger PLUS Based on the Value of the Worst Performing of the NASDAQ-100 Index ® , the Russell 2000 ® Index and the Dow Jones Industrial Average SM due August 13, 2026

Trigger Performance Leveraged Upside Securities SM

Fully and Unconditionally Guaranteed by Morgan Stanley

Principal at Risk Securities

The Trigger PLUS are unsecured obligations of Morgan Stanley Finance LLC (“MSFL”) and are fully and unconditionally guaranteed by Morgan Stanley. The Trigger PLUS do not guarantee any return of principal, will pay a fixed quarterly coupon (including at maturity) at the rate specified below and have the terms described in the accompanying product supplement for PLUS, index supplement and prospectus, as supplemented or modified by this document. The payment at maturity on the Trigger PLUS will be based on the value of the worst performing of the NASDAQ-100 Index ® , the Russell 2000 ® Index and the Dow Jones Industrial Average SM , which we refer to as the underlying indices. At maturity, investors will receive the final quarterly coupon payment as well as a payment at maturity determined as follows: if each underlying index has appreciated in value, investors will receive the stated principal amount of their investment plus leveraged upside performance of the worst performing underlying index, subject to the maximum payment at maturity. If any of the underlying indices depreciates in value, but the final index value of each underlying index is greater than or equal to 50% of the respective initial index value, which we refer to as the respective trigger level, investors will receive the stated principal amount of their investment. However, if the final index value of any underlying index is less than its respective trigger level, investors will lose a significant portion or all of their investment, resulting in a loss of 1% for every 1% decline in the worst performing underlying index from its initial index value. Investors may lose their entire initial investment in the Trigger PLUS. Because the payment at maturity of the Trigger PLUS is based on the worst performing of the underlying indices, a decline in any underlying index below its respective trigger level will result in a significant loss of your investment, even if the other underlying indices have appreciated or have not declined as much. These long-dated Trigger PLUS are for investors who seek an equity index-based return and who are willing to risk their principal, risk exposure to the worst performing of three underlying indices and forgo current income and upside above the maximum payment at maturity in exchange for the upside leverage feature and the limited protection against loss that applies only if the final index value of each underlying index is greater than or equal to the respective trigger level. The Trigger PLUS are notes issued as part of MSFL’s Series A Global Medium-Term Notes program.

All payments are subject to our credit risk. If we default on our obligations, you could lose some or all of your investment. These Trigger PLUS are not secured obligations and you will not have any security interest in, or otherwise have any access to, any underlying reference asset or assets.

FINAL TERMS — Issuer: Morgan Stanley Finance LLC
Guarantor: Morgan Stanley
Maturity date: August 13, 2026
Underlying indices: NASDAQ-100 Index ® (the “NDX Index”), Russell 2000 ® Index (the “RTY Index”) and Dow Jones Industrial Average SM (the “INDU Index”)
Valuation date: August 10, 2026, subject to postponement for non-index business days and certain market disruption events
Aggregate principal amount: $336,000
Quarterly coupon: A fixed quarterly coupon at an annual rate of 1.00% (corresponding to $2.50 per quarter per Trigger PLUS) will be paid on each coupon payment date.
Coupon payment dates: November 15, 2021, February 14, 2022, May 12, 2022, August 12, 2022, November 15, 2022, February 14, 2023, May 12, 2023, August 14, 2023, November 14, 2023, February 14, 2024, May 14, 2024, August 14, 2024, November 14, 2024, February 13, 2025, May 14, 2025, August 14, 2025, November 14, 2025, February 12, 2026, May 14, 2026 and the maturity date; provided that if any such day is not a business day, that quarterly coupon payment will be made on the next succeeding business day and no adjustment will be made to any quarterly coupon payment made on that succeeding business day. The final quarterly coupon payment will be made on the maturity date.
Payment at maturity: At maturity, in addition to the final quarterly coupon payment, investors will receive a payment at maturity determined as follows: If the final index value of each underlying index is greater than its respective initial index value, $1,000 + leveraged upside payment In no event will the payment at maturity exceed the maximum payment at maturity. If the final index value of any underlying index is less than or equal to its respective initial index value, but the final index value of each underlying index is greater than or equal to its respective trigger level: $1,000 If the final index value of any underlying index is less than its respective trigger level: $1,000 × index performance factor of the worst performing underlying index Under these circumstances, the payment at maturity will be less than the stated principal amount of $1,000 and will represent a loss of at least 50%, and possibly all of your investment (aside from the final quarterly coupon payment).
Leveraged upside payment: $1,000 × leverage factor × index percent change of the worst performing underlying index
Leverage factor: 110% (applicable only if the final index value of each underlying index is greater than its respective initial index value)
Index percent change: With respect to each underlying index, (final index value – initial index value) / initial index value
Worst performing underlying index: The underlying index with the lowest index percent change
Index performance factor: With respect to each underlying index, final index value / initial index value
Maximum payment at maturity: $1,255 per Trigger PLUS (125.50% of the stated principal amount)
Initial index value: With respect to the NDX Index, 15,133.11, which is the index closing value of such index on the pricing date With respect to the RTY Index, 2,234.808, which is the index closing value of such index on the pricing date With respect to the INDU Index, 35,101.85, which is the index closing value of such index on the pricing date
Final index value: With respect to each underlying index, the index closing value of such index on the valuation date
Trigger level: With respect to the NDX Index, 7,566.555, which is 50% of the initial index value of such index With respect to the RTY Index, 1,117.404, which is 50% of the initial index value of such index With respect to the INDU Index, 17,550.925, which is 50% of the initial index value of such index
Stated principal amount / Issue price: $1,000 per Trigger PLUS (see “Commissions and issue price” below)
Pricing date: August 9, 2021
Original issue date: August 12, 2021 (3 business days after the pricing date)
CUSIP / ISIN: 61773FLS0 / US61773FLS01
Listing: The Trigger PLUS will not be listed on any securities exchange.
Agent: Morgan Stanley & Co. LLC (“MS & Co.”), an affiliate of MSFL and a wholly owned subsidiary of Morgan Stanley. See “Supplemental information regarding plan of distribution; conflicts of interest.”
Estimated value on the pricing date: $920.10 per Trigger PLUS. See “Investment Summary” beginning on page 2.
Commissions and issue price: Price to public Agent’s commissions (1) Proceeds to us (2)
Per Trigger PLUS $1,000 $36.25 $963.75
Total $336,000 $12,180 $323,820

[if IE]<![endif] (1) [if IE]<![endif] Selected dealers and their financial advisors will collectively receive from the agent, MS & Co., a fixed sales commission of $36.25 for each Trigger PLUS they sell. See “Supplemental information regarding plan of distribution; conflicts of interest.” For additional information, see “Plan of Distribution (Conflicts of Interest)” in the accompanying product supplement for PLUS.

[if IE]<![endif] (2) [if IE]<![endif] See “Use of proceeds and hedging” on page 26.

The Trigger PLUS involve risks not associated with an investment in ordinary debt securities. See “Risk Factors” beginning on page 9.

The Securities and Exchange Commission and state securities regulators have not approved or disapproved these securities, or determined if this document or the accompanying product supplement, index supplement and prospectus is truthful or complete. Any representation to the contrary is a criminal offense.

The Trigger PLUS are not deposits or savings accounts and are not insured by the Federal Deposit Insurance Corporation or any other governmental agency or instrumentality, nor are they obligations of, or guaranteed by, a bank.

You should read this document together with the related product supplement, index supplement and prospectus, each of which can be accessed via the hyperlinks below. Please also see “Additional Terms of the Trigger PLUS” and “Additional Information About the Trigger PLUS” at the end of this document.

As used in this document, “we,” “us” and “our” refer to Morgan Stanley or MSFL, or Morgan Stanley and MSFL collectively, as the context requires.

Product Supplement for PLUS dated November 16, 2020 Index Supplement dated November 16, 2020 Prospectus dated November 16, 2020

Morgan Stanley Finance LLC

Trigger PLUS Based on the Value of the Worst Performing of the NASDAQ-100 Index ® , the Russell 2000 ® Index and the Dow Jones Industrial Average SM due August 13, 2026

Trigger Performance Leveraged Upside Securities SM

Principal at Risk Securities

Investment Summary

Performance Leveraged Upside Securities

The Trigger PLUS Based on the Value of the Worst Performing of the NASDAQ-100 Index ® , the Russell 2000 ® Index and the Dow Jones Industrial Average SM due August 13, 2026 (the “Trigger PLUS”) can be used:

[if IE]<![endif] ■ [if IE]<![endif] As an alternative to direct exposure to the underlying indices that enhances returns for a certain range of positive performance of the worst performing underlying index, subject to the maximum payment at maturity

[if IE]<![endif] ■ [if IE]<![endif] To obtain a fixed quarterly coupon at a rate of 1.00% per annum

[if IE]<![endif] ■ [if IE]<![endif] To potentially outperform the worst performing of the NASDAQ-100 Index ® , the Russell 2000 ® Index and the Dow Jones Industrial Average SM in a moderately bullish scenario by taking advantage of the leverage factor

[if IE]<![endif] ■ [if IE]<![endif] To provide limited protection against loss of principal in the event of a decline of the underlying indices but only if the respective final index level of the worst performing underlying index is greater than or equal to the respective trigger level

Maturity: Approximately 5 years
Quarterly coupon: A fixed quarterly coupon at an annual rate of 1.00% (corresponding to $2.50 per quarter per Trigger PLUS) will be paid on each coupon payment date.
Leverage factor: 110% (applicable only if the final index value of each underlying index is greater than its respective initial index value).
Maximum payment at maturity: $1,255 per Trigger PLUS (125.50% of the stated principal amount)
Trigger level: With respect to the NDX Index, 50% of the initial index value With respect to the RTY Index, 50% of the initial index value With respect to the INDU Index, 50% of the initial index value
Minimum payment at maturity: None. You could lose your entire initial investment in the Trigger PLUS.

The original issue price of each Trigger PLUS is $1,000. This price includes costs associated with issuing, selling, structuring and hedging the Trigger PLUS, which are borne by you, and, consequently, the estimated value of the Trigger PLUS on the pricing date is less than $1,000. We estimate that the value of each Trigger PLUS on the pricing date is $920.10.

What goes into the estimated value on the pricing date?

In valuing the Trigger PLUS on the pricing date, we take into account that the Trigger PLUS comprise both a debt component and a performance-based component linked to the underlying indices. The estimated value of the Trigger PLUS is determined using our own pricing and valuation models, market inputs and assumptions relating to the underlying indices, instruments based on the underlying indices, volatility and other factors including current and expected interest rates, as well as an interest rate related to our secondary market credit spread, which is the implied interest rate at which our conventional fixed rate debt trades in the secondary market.

What determines the economic terms of the Trigger PLUS?

In determining the economic terms of the Trigger PLUS, including the leverage factor, the trigger levels, the maximum payment at maturity and the quarterly coupon rate, we use an internal funding rate, which is likely to be lower than our secondary market credit spreads and therefore advantageous to us. If the issuing, selling, structuring and hedging costs borne by you were lower or if the internal funding rate were higher, one or more of the economic terms of the Trigger PLUS would be more favorable to you.

What is the relationship between the estimated value on the pricing date and the secondary market price of the Trigger PLUS?

The price at which MS & Co. purchases the Trigger PLUS in the secondary market, absent changes in market conditions, including those related to the underlying indices, may vary from, and be lower than, the estimated value on the pricing date, because the

August 2021 Page 2

Morgan Stanley Finance LLC

Trigger PLUS Based on the Value of the Worst Performing of the NASDAQ-100 Index ® , the Russell 2000 ® Index and the Dow Jones Industrial Average SM due August 13, 2026

Trigger Performance Leveraged Upside Securities SM

Principal at Risk Securities

secondary market price takes into account our secondary market credit spread as well as the bid-offer spread that MS & Co. would charge in a secondary market transaction of this type and other factors. However, because the costs associated with issuing, selling, structuring and hedging the Trigger PLUS are not fully deducted upon issuance, for a period of up to 6 months following the issue date, to the extent that MS & Co. may buy or sell the Trigger PLUS in the secondary market, absent changes in market conditions, including those related to the underlying indices, and to our secondary market credit spreads, it would do so based on values higher than the estimated value. We expect that those higher values will also be reflected in your brokerage account statements.

MS & Co. may, but is not obligated to, make a market in the Trigger PLUS, and, if it once chooses to make a market, may cease doing so at any time.

August 2021 Page 3

Morgan Stanley Finance LLC

Trigger PLUS Based on the Value of the Worst Performing of the NASDAQ-100 Index ® , the Russell 2000 ® Index and the Dow Jones Industrial Average SM due August 13, 2026

Trigger Performance Leveraged Upside Securities SM

Principal at Risk Securities

Key Investment Rationale

The Trigger PLUS pay a fixed quarterly coupon (including at maturity) at the rate specified herein and offer leveraged upside exposure to the worst performing of the NASDAQ-100 Index ® , the Russell 2000 ® Index and the Dow Jones Industrial Average SM , subject to the maximum payment at maturity. In exchange for the leverage feature, investors are exposed to the risk of loss of a significant portion or all of their investment (aside from the final quarterly coupon payment) due to the trigger feature. At maturity, an investor will receive an amount in cash based upon the closing value of the worst performing underlying index on the valuation date. The Trigger PLUS are unsecured obligations of ours, and all payments on the Trigger PLUS are subject to our credit risk. Investors may lose their entire initial investment in the Trigger PLUS.

Quarterly Coupon The securities will pay a fixed quarterly coupon at an annual rate of 1.00% (corresponding to $2.50 per quarter per Trigger PLUS) on each coupon payment date.
Leveraged Performance Up to a Cap The Trigger PLUS offer investors an opportunity to receive, in addition to the final quarterly coupon payment, 110% of the positive return of the worst performing of the underlying indices, subject to the maximum payment at maturity, if each underlying index has appreciated in value.
Trigger Feature At maturity, even if the worst performing underlying index has declined over the term of the Trigger PLUS, you will receive, in addition to the final quarterly coupon payment, your stated principal amount but only if the final index value of the worst performing underlying index is greater than or equal to the respective trigger level.
Upside Scenario Each underlying index increases in value and, at maturity, in addition to the final quarterly coupon payment, the Trigger PLUS redeem for the stated principal amount of $1,000 plus 110% of the index percent change of the worst performing underlying index, subject to the maximum payment at maturity of $1,255 per Trigger PLUS (125.50% of the stated principal amount).
Par Scenario The final index value of the worst performing index is less than or equal to the respective initial index value but is greater than or equal to the respective trigger level. In this case, in addition to the final quarterly coupon payment, you receive the stated principal amount of $1,000 at maturity even though the worst performing underlying index has depreciated.
Downside Scenario Any underlying index declines in value such that, at maturity, the final index value of the worst performing index is less than the respective trigger level. In this case, investors will receive the final quarterly coupon payment, but the Trigger PLUS will redeem for at least 50% less than the stated principal amount, and this decrease will be by an amount proportionate to the full decline in value of the worst performing underlying index over the term of the Trigger PLUS. Because the payment at maturity of the Trigger PLUS is based on the worst performing of the underlying indices, a decline in any underlying index below its respective trigger level will result in a significant loss of your investment, even if the other underlying indices have appreciated or have not declined as much.

August 2021 Page 4

Morgan Stanley Finance LLC

Trigger PLUS Based on the Value of the Worst Performing of the NASDAQ-100 Index ® , the Russell 2000 ® Index and the Dow Jones Industrial Average SM due August 13, 2026

Trigger Performance Leveraged Upside Securities SM

Principal at Risk Securities

Hypothetical Examples

The following hypothetical examples illustrate how to calculate the payment at maturity on the Trigger PLUS. The following examples are for illustrative purposes only. You will receive a fixed quarterly coupon (including at maturity) at a rate of 1.00% per annum regardless of the performance of the underlying indices. The actual initial index value and trigger level for each underlying index are set forth on the cover page of this pricing supplement. The payment at maturity on the Trigger PLUS is subject to our credit risk. The below examples are based on the following terms:

Stated principal amount: $1,000 per PLUS
Quarterly coupon: A fixed quarterly coupon at an annual rate of 1.00% (corresponding to $2.50 per quarter per Trigger PLUS) is paid on each coupon payment date.
Leverage factor: 110%
Maximum payment at maturity: $1,255 per Trigger PLUS (125.50% of the stated principal amount)
Hypothetical trigger level: With respect to the NDX Index, 6,000, 50% of the respective hypothetical initial index value With respect to the RTY Index, 750, 50% of the respective hypothetical initial index value With respect to the INDU Index, 15,000, 50% of the respective hypothetical initial index value
Hypothetical initial index value: With respect to the NDX Index: 12,000 With respect to the RTY Index: 1,500 With respect to the INDU Index: 30,000

EXAMPLE 1 : Each underlying index appreciates significantly and so investors receive only the maximum payment at maturity.

Final index value NDX Index: 22,800
RTY Index: 2,700
INDU Index: 58,500
Index percent change NDX Index: (22,800 – 12,000) / 12,000 = 90% RTY Index: (2,700 – 1,500) / 1,500 = 80% INDU Index: (58,500 – 30,000) / 30,000 = 95%
Payment at maturity (in addition to the final annual coupon payment) = $1,000 + leveraged upside payment , subject to the maximum payment at maturity

August 2021 Page 5

Morgan Stanley Finance LLC

Trigger PLUS Based on the Value of the Worst Performing of the NASDAQ-100 Index ® , the Russell 2000 ® Index and the Dow Jones Industrial Average SM due August 13, 2026

Trigger Performance Leveraged Upside Securities SM

Principal at Risk Securities

= $1,000 + ($1,000 × leverage factor × index percent change of the worst performing underlying index), subject to the maximum payment at maturity
= $1,000 + ($1,000 × 110% × 80%), subject to the maximum payment at maturity
= maximum payment at maturity of $1,255 per Trigger PLUS

In example 1, the final index value of each of the NDX Index, the RTY Index and the INDU Index is significantly greater than its initial index value. The NDX Index has appreciated by 90%, the RTY Index has appreciated by 80% and the INDU Index has appreciated by 95%. Therefore, investors receive at maturity, in addition to the final quarterly coupon payment, the stated principal amount plus 110% of the appreciation of the worst performing underlying index, subject to the maximum payment at maturity of $1,255 per Trigger PLUS. Under the terms of the Trigger PLUS, investors will realize the maximum payment at maturity at a final index value of the worst performing underlying index of approximately 123.182% of its respective initial index value. Therefore, in this example, in addition to the final quarterly coupon payment, investors receive only the maximum payment at maturity of $1,255 per stated principal amount, even though each underlying index has appreciated significantly.

EXAMPLE 2 : Each underlying index appreciates over the term of the Trigger PLUS, and investors receive the stated principal amount plus the leveraged upside payment, calculated based on the index percent change of the worst performing underlying index.

Final index value NDX Index: 12,600
RTY Index: 2,100
INDU Index: 36,000
Index percent change NDX Index: (12,600 – 12,000) / 12,000 = 5% RTY Index: (2,100 – 1,500) / 1,500 = 40% INDU Index: (36,000 – 30,000) / 30,000 = 20%
Payment at maturity (in addition to the final quarterly coupon payment) = $1,000 + leveraged upside payment, subject to the maximum payment at maturity
= $1,000 + ($1,000 × leverage factor × index percent change of the worst performing underlying index) , subject to the maximum payment at maturity
= $1,000 + ($1,000 × 110% × 5%), subject to the maximum payment at maturity
= $1,055

In example 2, the final index value of each of the NDX Index, the RTY Index and the INDU Index is greater than its initial index value. The NDX Index has appreciated by 5%, the RTY Index has appreciated by 40% and the INDU Index has appreciated by 20%. Therefore, investors receive at maturity, in addition to the final quarterly coupon payment, the stated principal amount plus 110% of the appreciation of the worst performing underlying index, which is the NDX Index in this example. Investors receive $1,055 per Trigger PLUS at maturity, in addition to the final quarterly coupon payment.

EXAMPLE 3 : One underlying index appreciates, while the other two underlying indices decline over the term of the Trigger PLUS but no index declines below the respective trigger level, and investors receive the stated principal amount.

Final index value
RTY Index: 1,200
INDU Index: 25,500

August 2021 Page 6

Morgan Stanley Finance LLC

Trigger PLUS Based on the Value of the Worst Performing of the NASDAQ-100 Index ® , the Russell 2000 ® Index and the Dow Jones Industrial Average SM due August 13, 2026

Trigger Performance Leveraged Upside Securities SM

Principal at Risk Securities

Index percent change NDX Index: (15,600 – 12,000) / 12,000 = 30% RTY Index: (1,200 – 1,500) / 1,500 = -20% INDU Index: (25,500 – 30,000) / 30,000 = -15%
Payment at maturity (in addition to the final quarterly coupon payment) = $1,000

In example 3, the final index value of the NDX Index is greater than its initial index value, while the final index values of the RTY Index and the INDU Index are less than their respective initial index values, but are greater than or equal to their respective trigger levels. The NDX Index has appreciated by 30% while the RTY index has declined by 20% and the INDU Index has declined by 15%. Investors will receive the stated principal amount of $1,000, in addition to the final quarterly coupon payment.

EXAMPLE 4 : Two underlying indices appreciate while one underlying index declines over the term of the Trigger PLUS, and the final index value of the worst performing underlying index is less than the respective trigger level. Investors are therefore exposed to the decline in the worst performing underlying index from its initial index value.

Final index value NDX Index: 15,600
RTY Index: 600
INDU Index: 31,500
Index percent change NDX Index: (15,600 – 12,000) / 12,000 = 30% RTY Index: (600 – 1,500) / 1,500 = -60% INDU Index: (31,500 – 30,000) / 30,000 = 5%
Payment at maturity (in addition to the final quarterly coupon payment) = $1,000 × (index performance factor of the worst performing index)
= $1,000 × (600 / 1,500)
= $400

In example 4, the final index values of the NDX Index and the INDU Index are greater than their respective initial index values, while the final index value of the RTY Index has declined below the trigger level. The NDX Index has appreciated by 30%, the INDU Index has appreciated by 5% and the RTY Index has depreciated by 60%. Because the final index value of the RTY Index has declined below the trigger level, investors receive the final quarterly coupon payment but are exposed to the negative performance of the RTY Index, which is the worst performing underlying index in this example. Investors receive a payment at maturity of $400, in addition to the final quarterly coupon payment.

EXAMPLE 5 : Each underlying index declines below its respective trigger level, and investors are therefore exposed to the decline in the worst performing underlying index from its initial index value.

Final index value NDX Index: 3,600
RTY Index: 600
INDU Index: 13,500
Index percent change NDX Index: (3,600 – 12,000) / 12,000 = -70% RTY Index: (600 – 1,500) / 1,500 = -60% INDU Index: (13,500 – 30,000) / 30,000 = -55%
Payment at maturity (in addition to the final quarterly coupon payment) = $1,000 × (index performance factor of the worst performing index)
= $1,000 × (3,600 / 12,000)
= $300

August 2021 Page 7

Morgan Stanley Finance LLC

Trigger PLUS Based on the Value of the Worst Performing of the NASDAQ-100 Index ® , the Russell 2000 ® Index and the Dow Jones Industrial Average SM due August 13, 2026

Trigger Performance Leveraged Upside Securities SM

Principal at Risk Securities

In example 5, the final index value of each of the NDX Index, the RTY Index and the INDU Index is less than its respective trigger level. The NDX Index has declined by 70%, the RTY Index has declined by 60% and the INDU Index has declined by 55%. Therefore, investors receive the final quarterly coupon payment but are exposed to the negative performance of the NDX Index, which is the worst performing underlying index in this example. Investors receive a payment at maturity of $300, in addition to the final quarterly coupon payment.

Because the payment at maturity of the Trigger PLUS is based on the worst performing of the underlying indices, a decline in any underlying index below its respective trigger level will result in a significant loss of your investment, even if the other underlying indices have appreciated or have not declined as much .

August 2021 Page 8

Morgan Stanley Finance LLC

Trigger PLUS Based on the Value of the Worst Performing of the NASDAQ-100 Index ® , the Russell 2000 ® Index and the Dow Jones Industrial Average SM due August 13, 2026

Trigger Performance Leveraged Upside Securities SM

Principal at Risk Securities

Risk Factors

This section describes the material risks relating to the Trigger PLUS. For further discussion of these and other risks, you should read the section entitled “Risk Factors” in the accompanying product supplement for PLUS, index supplement and prospectus. We also urge you to consult your investment, legal, tax, accounting and other advisers in connection with your investment in the Trigger PLUS.

Risks Relating to an Investment in the Trigger PLUS

[if IE]<![endif] ■ [if IE]<![endif] The Trigger PLUS do not guarantee return of any principal. The terms of the Trigger PLUS differ from those of ordinary debt securities in that the Trigger PLUS do not guarantee payment of any principal at maturity. If the final index value of any underlying index is less than the respective trigger level (which is 50% of the respective initial index level), the payout at maturity (aside from the final quarterly coupon payment) will be an amount in cash that is at least 50% less than the $1,000 stated principal amount of each Trigger PLUS, and this decrease will be by an amount proportionate to the full decrease in the value of the worst performing underlying index over the term of the Trigger PLUS. There is no minimum payment at maturity on the Trigger PLUS (aside from the final quarterly coupon payment), and you could lose your entire investment.

[if IE]<![endif] ■ [if IE]<![endif] The appreciation potential of the Trigger PLUS is limited by the maximum payment at maturity. The appreciation potential of the Trigger PLUS is limited by the maximum payment at maturity (aside from the final quarterly coupon payment) of $1,255 per Trigger PLUS, or 125.50% of the stated principal amount. Although the leverage factor provides leveraged upside returns if the final index value of each underlying index is greater than its respective initial index value, because the payment at maturity will be limited to 125.50% of the stated principal amount for the Trigger PLUS, any increase in the final index value of the worst performing underlying index over its initial index value by more than approximately 23.182% of its initial index value will not further increase the return on the Trigger PLUS.

[if IE]<![endif] ■ [if IE]<![endif] The market price will be influenced by many unpredictable factors. Several factors will influence the value of the Trigger PLUS in the secondary market and the price at which MS & Co. may be willing to purchase or sell the Trigger PLUS in the secondary market, including the value, volatility and dividend yield of the underlying indices, interest and yield rates, time remaining to maturity, geopolitical conditions and economic, financial, political and regulatory or judicial events and any actual or anticipated changes in our credit ratings or credit spreads. Generally, the longer the time remaining to maturity, the more the market price of the Trigger PLUS will be affected by the other factors described above. The levels of the underlying indices may be, and have recently been, extremely volatile, and we can give you no assurance that the volatility will lessen. See “NASDAQ-100 Index ® Overview,” “Russell 2000 ® Index Overview” and “Dow Jones Industrial Average SM Overview” below. You may receive less, and possibly significantly less, than the stated principal amount per Trigger PLUS if you try to sell your Trigger PLUS prior to maturity.

[if IE]<![endif] ■ [if IE]<![endif] The Trigger PLUS are subject to our credit risk, and any actual or anticipated changes to our credit ratings or credit spreads may adversely affect the market value of the Trigger PLUS. You are dependent on our ability to pay all amounts due on the Trigger PLUS at maturity or on any coupon payment date, and therefore you are subject to our credit risk. If we default on our obligations under the Trigger PLUS, your investment would be at risk and you could lose some or all of your investment. As a result, the market value of the Trigger PLUS prior to maturity will be affected by changes in the market’s view of our creditworthiness. Any actual or anticipated decline in our credit ratings or increase in the credit spreads charged by the market for taking our credit risk is likely to adversely affect the market value of the Trigger PLUS.

[if IE]<![endif] ■ [if IE]<![endif] As a finance subsidiary, MSFL has no independent operations and will have no independent assets. As a finance subsidiary, MSFL has no independent operations beyond the issuance and administration of its securities and will have no independent assets available for distributions to holders of MSFL securities if they make claims in respect of such securities in a bankruptcy, resolution or similar proceeding. Accordingly, any recoveries by such holders will be limited to those available under the related guarantee by Morgan Stanley and that guarantee will rank pari passu with all other unsecured, unsubordinated obligations of Morgan Stanley. Holders will have

August 2021 Page 9

Morgan Stanley Finance LLC

Trigger PLUS Based on the Value of the Worst Performing of the NASDAQ-100 Index ® , the Russell 2000 ® Index and the Dow Jones Industrial Average SM due August 13, 2026

Trigger Performance Leveraged Upside Securities SM

Principal at Risk Securities

recourse only to a single claim against Morgan Stanley and its assets under the guarantee. Holders of securities issued by MSFL should accordingly assume that in any such proceedings they would not have any priority over and should be treated pari passu with the claims of other unsecured, unsubordinated creditors of Morgan Stanley, including holders of Morgan Stanley-issued securities.

[if IE]<![endif] ■ [if IE]<![endif] The amount payable on the Trigger PLUS is not linked to the values of the underlying indices at any time other than the valuation date. The final index value of each underlying index will be based on the index closing value of such index on the valuation date, subject to adjustment for non-index business days and certain market disruption events. Even if each underlying index appreciates prior to the valuation date but the value of any underlying index drops by the valuation date to below its trigger level, the payment at maturity will be significantly less than it would have been had the payment at maturity been linked to the values of the underlying indices prior to such drop. Although the actual values of the underlying indices on the stated maturity date or at other times during the term of the Trigger PLUS may be higher than their respective final index values, the payment at maturity will be based solely on the index closing values on the valuation date.

[if IE]<![endif] ■ [if IE]<![endif] Investing in the Trigger PLUS is not equivalent to investing in the underlying indices. Investing in the Trigger PLUS is not equivalent to investing in any underlying index or the component stocks of any underlying index. Investors in the Trigger PLUS will not have voting rights or rights to receive dividends or other distributions or any other rights with respect to stocks that constitute the underlying indices.

[if IE]<![endif] ■ [if IE]<![endif] The rate we are willing to pay for securities of this type, maturity and issuance size is likely to be lower than the rate implied by our secondary market credit spreads and advantageous to us. Both the lower rate and the inclusion of costs associated with issuing, selling, structuring and hedging the Trigger PLUS in the original issue price reduce the economic terms of the Trigger PLUS, cause the estimated value of the Trigger PLUS to be less than the original issue price and will adversely affect secondary market prices. Assuming no change in market conditions or any other relevant factors, the prices, if any, at which dealers, including MS & Co., may be willing to purchase the Trigger PLUS in secondary market transactions will likely be significantly lower than the original issue price, because secondary market prices will exclude the issuing, selling, structuring and hedging-related costs that are included in the original issue price and borne by you and because the secondary market prices will reflect our secondary market credit spreads and the bid-offer spread that any dealer would charge in a secondary market transaction of this type as well as other factors.

The inclusion of the costs of issuing, selling, structuring and hedging the Trigger PLUS in the original issue price and the lower rate we are willing to pay as issuer make the economic terms of the Trigger PLUS less favorable to you than they otherwise would be.

However, because the costs associated with issuing, selling, structuring and hedging the Trigger PLUS are not fully deducted upon issuance, for a period of up to 6 months following the issue date, to the extent that MS & Co. may buy or sell the Trigger PLUS in the secondary market, absent changes in market conditions, including those related to the underlying indices, and to our secondary market credit spreads, it would do so based on values higher than the estimated value, and we expect that those higher values will also be reflected in your brokerage account statements.

[if IE]<![endif] ■ [if IE]<![endif] The Trigger PLUS will not be listed on any securities exchange and secondary trading may be limited. The Trigger PLUS will not be listed on any securities exchange. Therefore, there may be little or no secondary market for the Trigger PLUS. MS & Co. may, but is not obligated to, make a market in the Trigger PLUS. Even if there is a secondary market, it may not provide enough liquidity to allow you to trade or sell the Trigger PLUS easily. Because we do not expect that other broker-dealers will participate significantly in the secondary market for the Trigger PLUS, the price at which you may be able to trade your Trigger PLUS is likely to depend on the price, if any, at which MS & Co. is willing to transact. If, at any time, MS & Co. were not to make a market in the Trigger PLUS, it is likely that there would be no secondary market for the Trigger PLUS. Accordingly, you should be willing to hold your Trigger PLUS to maturity.

[if IE]<![endif] ■ [if IE]<![endif] The estimated value of the Trigger PLUS is determined by reference to our pricing and valuation models, which may differ from those of other dealers and is not a maximum or minimum secondary market price.

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These pricing and valuation models are proprietary and rely in part on subjective views of certain market inputs and certain assumptions about future events, which may prove to be incorrect. As a result, because there is no market-standard way to value these types of securities, our models may yield a higher estimated value of the Trigger PLUS than those generated by others, including other dealers in the market, if they attempted to value the Trigger PLUS. In addition, the estimated value on the pricing date does not represent a minimum or maximum price at which dealers, including MS & Co., would be willing to purchase your Trigger PLUS in the secondary market (if any exists) at any time. The value of your Trigger PLUS at any time after the date of this document will vary based on many factors that cannot be predicted with accuracy, including our creditworthiness and changes in market conditions. See also “The market price will be influenced by many unpredictable factors” above.

[if IE]<![endif] ■ [if IE]<![endif] Hedging and trading activity by our affiliates could potentially adversely affect the value of the Trigger PLUS. One or more of our affiliates and/or third-party dealers expect to carry out hedging activities related to the Trigger PLUS (and to other instruments linked to the underlying index or its component stocks), including trading in the stocks that constitute the underlying indices as well as in other instruments related to the underlying indices. As a result, these entities may be unwinding or adjusting hedge positions during the term of the Trigger PLUS, and the hedging strategy may involve greater and more frequent dynamic adjustments to the hedge as the valuation date approaches. MS & Co. and some of our other affiliates also trade the stocks that constitute the underlying indices and other financial instruments related to the underlying indices on a regular basis as part of their general broker-dealer and other businesses. Any of these hedging or trading activities on or prior to the pricing date could potentially increase the initial index value of an underlying index, and, therefore, could increase the trigger level for such underlying index, which is the level at or above which such underlying index must close on the valuation date so that investors do not suffer a significant loss on their initial investment in the Trigger PLUS (depending also on the performance of the other underlying indices). Additionally, such hedging or trading activities during the term of the Trigger PLUS, including on the valuation date, could potentially affect whether the value of an underlying index on the valuation date is below the respective trigger level, and, therefore, whether an investor would receive significantly less than the stated principal amount of the Trigger PLUS at maturity (depending also on the performance of the other underlying indices).

[if IE]<![endif] ■ [if IE]<![endif] The calculation agent, which is a subsidiary of Morgan Stanley and an affiliate of MSFL, will make determinations with respect to the Trigger PLUS. As calculation agent, MS & Co. will determine the initial index values, the trigger levels and the final index values, including whether any underlying index has decreased to below the respective trigger level, and will calculate the amount of cash, if any, you will receive at maturity. Moreover, certain determinations made by MS & Co., in its capacity as calculation agent, may require it to exercise discretion and make subjective judgments, such as with respect to the occurrence or non-occurrence of market disruption events and the selection of a successor index or calculation of the final index value in the event of a market disruption event or discontinuance of the underlying indices. These potentially subjective determinations may adversely affect the payout to you at maturity, if any. For further information regarding these types of determinations, see “Description of PLUS—Postponement of Valuation Date(s)” and “—Calculation Agent and Calculations” and related definitions in the accompanying product supplement. In addition, MS & Co. has determined the estimated value of the Trigger PLUS on the pricing date.

[if IE]<![endif] ■ [if IE]<![endif] The U.S. federal income tax consequences of an investment in the Trigger PLUS are uncertain. There is no direct legal authority as to the proper treatment of the Trigger PLUS for U.S. federal income tax purposes, and, therefore, significant aspects of the tax treatment of the Trigger PLUS are uncertain.

Please read the discussion under “Additional Provisions—Tax considerations” in this document concerning the U.S. federal income tax consequences of an investment in the Trigger PLUS. We intend to treat a security for U.S. federal income tax purposes as a single financial contract that provides for a coupon that will be treated as gross income to you at the time received or accrued, in accordance with your regular method of tax accounting. Under this treatment, the ordinary income treatment of the coupon payments, in conjunction with the capital loss treatment of any loss recognized upon the sale, exchange or settlement of the Trigger PLUS, could result in adverse tax consequences to holders of the Trigger PLUS because the deductibility of capital losses is subject to limitations. We do not plan to request a ruling from the Internal Revenue Service (the “IRS”) regarding the tax treatment of the Trigger PLUS, and the IRS or a court may not agree with the tax treatment described herein. If the IRS were

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successful in asserting an alternative treatment for the Trigger PLUS, the timing and character of income or loss on the Trigger PLUS might differ significantly from the tax treatment described herein. For example, under one possible treatment, the IRS could seek to recharacterize the Trigger PLUS as debt instruments. In that event, U.S. Holders (as defined below) would be required to accrue into income original issue discount on the Trigger PLUS every year at a “comparable yield” determined at the time of issuance (as adjusted based on the difference, if any, between the actual and the projected amount of any contingent payments on the Trigger PLUS) and recognize all income and gain in respect of the Trigger PLUS as ordinary income. The risk that financial instruments providing for buffers, triggers or similar downside protection features, such as the Trigger PLUS , would be recharacterized as debt is greater than the risk of recharacterization for comparable financial instruments that do not have such features.

Non-U.S. Holders (as defined below) should note that we currently intend to withhold on any coupon paid to Non-U.S. Holders generally at a rate of 30%, or at a reduced rate specified by an applicable income tax treaty under an “other income” or similar provision, and will not be required to pay any additional amounts with respect to amounts withheld.

In 2007, the U.S. Treasury Department and the IRS released a notice requesting comments on the U.S. federal income tax treatment of “prepaid forward contracts” and similar instruments. While it is not clear whether the Trigger PLUS would be viewed as similar to the prepaid forward contracts described in the notice, it is possible that any Treasury regulations or other guidance promulgated after consideration of these issues could materially and adversely affect the tax consequences of an investment in the Trigger PLUS, possibly with retroactive effect. The notice focuses on a number of issues, the most relevant of which for holders of the Trigger PLUS are the character and timing of income or loss and the degree, if any, to which income realized by non-U.S. investors should be subject to withholding tax. Both U.S. and Non-U.S. Holders should consult their tax advisers regarding the U.S. federal income tax consequences of an investment in the Trigger PLUS, including possible alternative treatments, the issues presented by this notice and any tax consequences arising under the laws of any state, local or non-U.S. taxing jurisdiction.

Risks Relating to the Underlying Indices

[if IE]<![endif] ■ [if IE]<![endif] You are exposed to the price risk of each underlying index. Your return on the Trigger PLUS it not linked to a basket consisting of each underlying index. Rather, it will be based upon the independent performance of each underlying index. Unlike an instrument with a return linked to a basket of underlying assets, in which risk is mitigated and diversified among all the components of the basket, you will be exposed to the risks related to each underlying index. Poor performance by any underlying index over the term of the Trigger PLUS will negatively affect your return and will not be offset or mitigated by any positive performance by the other underlying indices. If any underlying index declines to below its respective trigger level as of the valuation date, you will be exposed to the negative performance of the worst performing underlying index at maturity, even if the other underlying indices have appreciated or have not declined as much, and you will lose a significant portion or all of your investment. Accordingly, your investment is subject to the price risk of each underlying index.

[if IE]<![endif] ■ [if IE]<![endif] Because the Trigger PLUS are linked to the performance of the worst performing underlying index, you are exposed to greater risk of sustaining a significant loss on your investment than if the Trigger PLUS were linked to just one underlying index. The risk that you will suffer a significant loss on your investment is greater if you invest in the Trigger PLUS as opposed to substantially similar securities that are linked to just the performance of one underlying index. With three underlying indices, it is more likely that any underlying index will decline to below its trigger level as of the valuation date, than if the Trigger PLUS were linked to only one underlying index. Therefore it is more likely that you will suffer a significant loss on your investment.

[if IE]<![endif] ■ [if IE]<![endif] The Trigger PLUS are linked to the Russell 2000 ® Index and are subject to risks associated with small-capitalization companies. As the Russell 2000 ® Index is one of the underlying indices, and the Russell 2000 ® Index consists of stocks issued by companies with relatively small market capitalization, the Trigger PLUS are linked to the value of small-capitalization companies. These companies often have greater stock price volatility, lower trading volume and less liquidity than large-capitalization companies and therefore the Russell 2000 ® Index may be more volatile than indices that consist of stocks issued by large-capitalization companies. Stock prices of

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small-capitalization companies are also more vulnerable than those of large-capitalization companies to adverse business and economic developments, and the stocks of small-capitalization companies may be thinly traded. In addition, small capitalization companies are typically less well-established and less stable financially than large-capitalization companies and may depend on a small number of key personnel, making them more vulnerable to loss of personnel. Such companies tend to have smaller revenues, less diverse product lines, smaller shares of their product or service markets, fewer financial resources and less competitive strengths than large-capitalization companies and are more susceptible to adverse developments related to their products.

[if IE]<![endif] ■ [if IE]<![endif] Adjustments to the underlying indices could adversely affect the value of the Trigger PLUS. The publisher of each underlying index may add, delete or substitute the stocks constituting such underlying index or make other methodological changes that could change the value of such underlying index. The publisher of each underlying index may discontinue or suspend calculation or publication of such underlying index at any time. In these circumstances, the calculation agent will have the sole discretion to substitute a successor index that is comparable to the discontinued underlying index and will be permitted to consider indices that are calculated and published by the calculation agent or any of its affiliates.

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NASDAQ-100 Index ® Overview

The NASDAQ-100 Index ® , which is calculated, maintained and published by Nasdaq, Inc., is a modified capitalization-weighted index of 100 of the largest and most actively traded equity securities of non-financial companies listed on The NASDAQ Stock Market LLC. The NASDAQ-100 Index ® includes companies across a variety of major industry groups. At any moment in time, the value of the NASDAQ-100 Index ® equals the aggregate value of the then-current NASDAQ-100 Index ® share weights of each of the NASDAQ-100 Index ® component securities, which are based on the total shares outstanding of each such NASDAQ-100 Index ® component security, multiplied by each such security’s respective last sale price on NASDAQ (which may be the official closing price published by NASDAQ), and divided by a scaling factor, which becomes the basis for the reported NASDAQ-100 Index ® value. For additional information about the NASDAQ-100 Index ® , see the information set forth under “NASDAQ-100 Index ® ” in the accompanying index supplement.

Information as of market close on August 9, 2021:

Bloomberg Ticker Symbol: NDX
Current Index Value: 15,133.11
52 Weeks Ago: 11,085.17
52 Week High (on 8/5/2021): 15,181.64
52 Week Low (on 9/23/2020): 10,833.33

The following graph sets forth the daily closing values of the NDX Index for the period from January 1, 2016 through August 9, 2021. The related table sets forth the published high and low closing values, as well as end-of-quarter closing values, of the NDX Index for each quarter in the same period. The closing value of the NDX Index on August 9, 2021 was 15,133.11. We obtained the information in the graph and table below from Bloomberg Financial Markets, without independent verification. The NDX Index has at times experienced periods of high volatility, and you should not take the historical values of the NDX Index as an indication of its future performance.

NDX Index Daily Closing Values January 1, 2016 to August 9, 2021

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NASDAQ-100 Index ® High Low Period End
2016
First Quarter 4,497.86 3,947.80 4,483.66
Second Quarter 4,565.42 4,201.06 4,417.70
Third Quarter 4,891.36 4,410.75 4,875.70
Fourth Quarter 4,965.81 4,660.46 4,863.62
2017
First Quarter 5,439.74 4,911.33 5,436.23
Second Quarter 5,885.30 5,353.59 5,646.92
Third Quarter 6,004.38 5,596.96 5,979.30
Fourth Quarter 6,513.27 5,981.92 6,396.42
2018
First Quarter 7,131.12 6,306.10 6,581.13
Second Quarter 7,280.71 6,390.84 7,040.80
Third Quarter 7,660.18 7,014.55 7,627.65
Fourth Quarter 7,645.45 5,899.35 6,329.96
2019
First Quarter 7,493.27 6,147.13 7,378.77
Second Quarter 7,845.73 6,978.02 7,671.08
Third Quarter 8,016.95 7,415.69 7,749.45
Fourth Quarter 8,778.31 7,550.79 8,733.07
2020
First Quarter 9,718.73 6,994.29 7,813.50
Second Quarter 10,209.82 7,486.29 10,156.85
Third Quarter 12,420.54 10,279.25 11,418.06
Fourth Quarter 12,888.28 11,052.95 12,888.28
2021
First Quarter 13,807.70 12,299.08 13,091.44
Second Quarter 14,572.75 13,001.63 14,554.80
Third Quarter (through August 9, 2021) 15,181.64 14,549.09 15,133.11

“Nasdaq ® ,” “NASDAQ-100 ® ” and “NASDAQ-100 Index ® ” are trademarks of Nasdaq, Inc. For more information, see “NASDAQ-100 Index ® ” in the accompanying index supplement.

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Russell 2000 ® Index Overview

The Russell 2000 ® Index is an index calculated, published and disseminated by FTSE Russell, and measures the composite price performance of stocks of 2,000 companies incorporated in the U.S. and its territories. All 2,000 stocks are traded on a major U.S. exchange and are the 2,000 smallest securities that form the Russell 3000 ® Index. The Russell 3000 ® Index is composed of the 3,000 largest U.S. companies as determined by market capitalization and represents approximately 98% of the U.S. equity market. The Russell 2000 ® Index consists of the smallest 2,000 companies included in the Russell 3000 ® Index and represents a small portion of the total market capitalization of the Russell 3000 ® Index. The Russell 2000 ® Index is designed to track the performance of the small capitalization segment of the U.S. equity market. For additional information about the Russell 2000 ® Index, see the information set forth under “Russell 2000 ® Index” in the accompanying index supplement.

Information as of market close on August 9, 2021:

Bloomberg Ticker Symbol: RTY
Current Index Value: 2,234.808
52 Weeks Ago: 1,584.670
52 Week High (on 3/15/2021): 2,360.168
52 Week Low (on 9/23/2020): 1,451.458

The following graph sets forth the daily closing values of the RTY Index for the period from January 1, 2016 through August 9, 2021. The related table sets forth the published high and low closing values, as well as end-of-quarter closing values, of the RTY Index for each quarter in the same period. The closing value of the RTY Index on August 9, 2021 was 2,234.808. We obtained the information in the graph and table below from Bloomberg Financial Markets, without independent verification. The RTY Index has at times experienced periods of high volatility, and you should not take the historical values of the RTY Index as an indication of its future performance.

RTY Index Daily Closing Values January 1, 2016 to August 9, 2021

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Russell 2000 ® Index High Low Period End
2016
First Quarter 1,114.028 953.715 1,114.028
Second Quarter 1,188.954 1,089.646 1,151.923
Third Quarter 1,263.438 1,139.453 1,251.646
Fourth Quarter 1,388.073 1,156.885 1,357.130
2017
First Quarter 1,413.635 1,345.598 1,385.920
Second Quarter 1,425.985 1,345.244 1,415.359
Third Quarter 1,490.861 1,356.905 1,490.861
Fourth Quarter 1,548.926 1,464.095 1,535.511
2018
First Quarter 1,610.706 1,463.793 1,529.427
Second Quarter 1,706.985 1,492.531 1,643.069
Third Quarter 1,740.753 1,653.132 1,696.571
Fourth Quarter 1,672.992 1,266.925 1,348.559
2019
First Quarter 1,590.062 1,330.831 1,539.739
Second Quarter 1,614.976 1,465.487 1,566.572
Third Quarter 1,585.599 1,456.039 1,523.373
Fourth Quarter 1,678.010 1,472.598 1,668.469
2020
First Quarter 1,705.215 991.160 1,153.103
Second Quarter 1,536.895 1,052.053 1,441.365
Third Quarter 1,592.287 1,398.920 1,507.692
Fourth Quarter 2,007.104 1,531.202 1,974.855
2021
First Quarter 2,360.168 1,945.914 2,220.519
Second Quarter 2,343.758 2,135.139 2,310.549
Third Quarter (through August 9, 2021) 2,329.359 2,130.680 2,234.808

The “Russell 2000 ® Index” is a trademark of FTSE Russell. For more information, see “Russell 2000 ® Index” in the accompanying index supplement.

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Dow Jones Industrial Average SM Overview

The Dow Jones Industrial Average SM is a price-weighted index composed of 30 common stocks that is published by S&P Dow Jones Indices LLC, the marketing name and a licensed trademark of CME Group Inc., as representative of the broad market of U.S. industry. For additional information about the Dow Jones Industrial Average SM , see the information set forth under “Dow Jones Industrial Average SM ” in the accompanying index supplement.

Information as of market close on August 9, 2021:

Bloomberg Ticker Symbol: INDU
Current Index Value: 35,101.85
52 Weeks Ago: 27,791.44
52 Week High (on 8/6/2021): 35,208.51
52 Week Low (on 10/30/2020): 26,501.60

The following graph sets forth the daily closing values of the INDU Index for the period from January 1, 2016 through August 9, 2021. The related table sets forth the published high and low closing values, as well as end-of-quarter closing values, of the INDU Index for each quarter in the same period. The closing value of the INDU Index on August 9, 2021 was 35,101.85. We obtained the information in the graph and table below from Bloomberg Financial Markets, without independent verification. The INDU Index has at times experienced periods of high volatility, and you should not take the historical values of the INDU Index as an indication of its future performance.

INDU Index Daily Closing Values January 1, 2016 to August 9, 2021

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Dow Jones Industrial Average SM High Low Period End
2016
First Quarter 17,716.66 15,660.18 17,685.09
Second Quarter 18,096.27 17,140.24 17,929.99
Third Quarter 18,636.05 17,840.62 18,308.15
Fourth Quarter 19,974.62 17,888.28 19,762.60
2017
First Quarter 21,115.55 19,732.40 20,663.22
Second Quarter 21,528.99 20,404.49 21,349.63
Third Quarter 22,412.59 21,320.04 22,405.09
Fourth Quarter 24,837.51 22,557.60 24,719.22
2018
First Quarter 26,616.71 23,533.20 24,103.11
Second Quarter 25,322.31 23,644.19 24,271.41
Third Quarter 26,743.50 24,174.82 26,458.31
Fourth Quarter 26,828.39 21,792.20 23,327.46
2019
First Quarter 26,091.95 22,686.22 25,928.68
Second Quarter 26,753.17 24,815.04 26,599.96
Third Quarter 27,359.16 25,479.42 26,916.83
Fourth Quarter 28,645.26 26,078.62 28,538.44
2020
First Quarter 29,551.42 18,591.93 21,917.16
Second Quarter 27,572.44 20,943.51 25,812.88
Third Quarter 29,100.50 25,706.09 27,781.70
Fourth Quarter 30,606.48 26,501.60 30,606.48
2021
First Quarter 33,171.37 29,982.62 32,981.55
Second Quarter 34,777.76 33,153.21 34,502.51
Third Quarter (through August 9, 2021) 35,208.51 33,962.04 35,101.85

“Dow Jones,” “Dow Jones Industrial Average,” “Dow Jones Indexes” and “DJIA” are service marks of Dow Jones Trademark Holdings LLC. For more information, see “Dow Jones Industrial Average SM ” in the accompanying index supplement.

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Additional Terms of the Trigger PLUS

Please read this information in conjunction with the summary terms on the front cover of this document.

Additional Terms:
If the terms described herein are inconsistent with those described in the accompanying product supplement, index supplement or prospectus, the terms described herein shall control.
Underlying index publisher: With respect to the NDX Index, Nasdaq, Inc., or any successor thereof. With respect to the RTY Index, FTSE Russell, or any successor thereof. With respect to the INDU Index, S&P Dow Jones Indices LLC, or any successor thereof.
Day-count convention: Interest will be computed on the basis of a 360-day year of twelve 30-day months.
Record Date: The record date for each coupon payment date shall be the date one business day prior to such scheduled coupon payment date; provided , however, that any coupon payable at maturity shall be payable to the person to whom the payment at maturity shall be payable.
Denominations: $1,000 per Trigger PLUS and integral multiples thereof
Interest period: The quarterly period from and including the original issue date (in the case of the first interest period) or the previous scheduled coupon payment date, as applicable, to but excluding the following scheduled coupon payment date, with no adjustment for any postponement thereof.
Trustee: The Bank of New York Mellon
Calculation agent: MS & Co.
Bull market or bear market PLUS: Bull market PLUS
Index closing value: With respect to each of the NDX Index and the INDU Index, the index closing value on any index business day shall be determined by the calculation agent and shall equal the official closing value of such underlying index, or any successor index, published at the regular official weekday close of trading on such index business day by the underlying index publisher for such underlying index. In certain circumstances, the index closing value for the NDX Index or the INDU Index shall be based on the alternate calculation of such underlying index described under “Discontinuance of Any Underlying Index or Basket Index; Alteration of Method of Calculation” in the accompanying product supplement. With respect to the RTY Index, the index closing value on any index business day shall be determined by the calculation agent and shall equal the closing value of the RTY Index, or any successor index reported by Bloomberg Financial Services, or any successor reporting service the calculation agent may select, on such index business day. In certain circumstances, the index closing value for the RTY Index shall be based on the alternate calculation of the RTY Index described under “Discontinuance of Any Underlying Index or Basket Index; Alteration of Method of Calculation” in the accompanying product supplement.
Postponement of maturity date: If the scheduled valuation date is not an index business day with respect to an underlying index or if a market disruption event occurs with respect to an underlying index on that day so that the valuation date is postponed and falls less than two business days prior to the scheduled maturity date, the maturity date of the Trigger PLUS will be postponed to the second business day following the latest valuation date as postponed with respect to such underlying index.
Issuer notice to registered security In the event that the maturity date is postponed due to postponement of the

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holders, the trustee and the depositary: valuation date, the issuer shall give notice of such postponement and, once it has been determined, of the date to which the maturity date has been rescheduled (i) to each registered holder of the Trigger PLUS by mailing notice of such postponement by first class mail, postage prepaid, to such registered holder’s last address as it shall appear upon the registry books, (ii) to the trustee by facsimile confirmed by mailing such notice to the trustee by first class mail, postage prepaid, at its New York office and (iii) to The Depository Trust Company (the “depositary”) by telephone or facsimile, confirmed by mailing such notice to the depositary by first class mail, postage prepaid. Any notice that is mailed to a registered holder of the Trigger PLUS in the manner herein provided shall be conclusively presumed to have been duly given to such registered holder, whether or not such registered holder receives the notice. The issuer shall give such notice as promptly as possible, and in no case later than (i) with respect to notice of postponement of the maturity date, the business day immediately preceding the scheduled maturity date, and (ii) with respect to notice of the date to which the maturity date has been rescheduled, the business day immediately following the actual valuation date. The issuer shall, or shall cause the calculation agent to, (i) provide written notice to the trustee, on which notice the trustee may conclusively rely, and to the depositary of the amount of cash to be delivered as quarterly coupon with respect to each Trigger PLUS on or prior to 10:30 a.m. (New York City time) on the business day preceding each coupon payment date, and (ii) deliver the aggregate cash amount due with respect to the applicable coupon to the trustee for delivery to the depositary, as holder of the Trigger PLUS, on the applicable coupon payment date. The issuer shall, or shall cause the calculation agent to, (i) provide written notice to the trustee, on which notice the trustee may conclusively rely, and to the depositary of the amount of cash, if any, to be delivered with respect to the Trigger PLUS, on or prior to 10:30 a.m. (New York City time) on the business day preceding the maturity date, and (ii) deliver the aggregate cash amount due with respect to the Trigger PLUS, if any, to the trustee for delivery to the depositary, as holder of the Trigger PLUS, on the maturity date.

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Additional Information About the Trigger PLUS
Additional Information:
Minimum ticketing size: $1,000 / 1 Trigger PLUS
Tax considerations: Prospective investors should note that the discussion under the section called “United States Federal Taxation” in the accompanying product supplement does not apply to the Trigger PLUS issued under this document and is superseded by the following discussion. The following is a general discussion of the material U.S. federal income tax consequences and certain estate tax consequences of the ownership and disposition of the Trigger PLUS . This discussion applies only to investors in the Trigger PLUS who: ● purchase the Trigger PLUS in the original offering; and ● hold the Trigger PLUS as capital assets within the meaning of Section 1221 of the Internal Revenue Code of 1986, as amended (the “Code”). This discussion does not describe all of the tax consequences that may be relevant to a holder in light of the holder’s particular circumstances or to holders subject to special rules, such as: ● certain financial institutions; ● insurance companies; ● certain dealers and traders in securities or commodities; ● investors holding the Trigger PLUS as part of a “straddle,” wash sale, conversion transaction, integrated transaction or constructive sale transaction; ● U.S. Holders (as defined below) whose functional currency is not the U.S. dollar; ● partnerships or other entities classified as partnerships for U.S. federal income tax purposes; ● regulated investment companies; ● real estate investment trusts; or ● tax-exempt entities, including “individual retirement accounts” or “Roth IRAs” as defined in Section 408 or 408A of the Code, respectively. If an entity that is classified as a partnership for U.S. federal income tax purposes holds the Trigger PLUS, the U.S. federal income tax treatment of a partner will generally depend on the status of the partner and the activities of the partnership. If you are a partnership holding the Trigger PLUS or a partner in such a partnership, you should consult your tax adviser as to the particular U.S. federal tax consequences of holding and disposing of the Trigger PLUS to you. In addition, we will not attempt to ascertain whether any issuer of any shares to which a Trigger PLUS relates (such shares hereafter referred to as “Underlying Shares”) is treated as a “passive foreign investment company” (“PFIC”) within the meaning of Section 1297 of the Code or as a “U.S. real property holding corporation” (“USRPHC”) within the meaning of Section 897 of the Code. If any issuer of Underlying Shares were so treated, certain adverse U.S. federal income tax consequences might apply, to a U.S. Holder in the case of a PFIC and to a Non-U.S. Holder in the case of a USRPHC, upon the sale, exchange or settlement of a Trigger PLUS . You should refer to information filed with the Securities and Exchange Commission or other governmental authorities by the issuers of the Underlying Shares and consult your tax adviser regarding the possible consequences to you if any issuer is or becomes a PFIC or USRPHC . As the law applicable to the U.S. federal income taxation of instruments such as the Trigger PLUS is technical and complex, the discussion below necessarily represents only a general summary. The effect of any applicable state, local or non-U.S. tax laws is not discussed, nor are any alternative minimum tax consequences or consequences resulting from the Medicare tax on investment income. Moreover, the discussion below does not address the consequences to taxpayers subject to special tax accounting rules under Section 451(b) of the Code. This discussion is based on the Code, administrative pronouncements, judicial decisions and final, temporary and proposed Treasury regulations, all as of the date hereof, changes to any of which subsequent to the date hereof may affect the

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tax consequences described herein. Persons considering the purchase of the Trigger PLUS should consult their tax advisers with regard to the application of the U.S. federal income tax laws to their particular situations as well as any tax consequences arising under the laws of any state, local or non-U.S. taxing jurisdiction. General Due to the absence of statutory, judicial or administrative authorities that directly address the treatment of the Trigger PLUS or instruments that are similar to the Trigger PLUS for U.S. federal income tax purposes, no assurance can be given that the IRS or a court will agree with the tax treatment described herein. We intend to treat a security for U.S. federal income tax purposes as a single financial contract that provides for a coupon that will be treated as gross income to you at the time received or accrued in accordance with your regular method of tax accounting. In the opinion of our counsel, Davis Polk & Wardwell LLP, this treatment of the Trigger PLUS is reasonable under current law; however, our counsel has advised us that it is unable to conclude affirmatively that this treatment is more likely than not to be upheld, and that alternative treatments are possible. You should consult your tax adviser regarding all aspects of the U.S. federal tax consequences of an investment in the Trigger PLUS (including possible alternative treatments of the Trigger PLUS ). Unless otherwise stated, the following discussion is based on the treatment of each security as described in the previous paragraph. Tax Consequences to U.S. Holders This section applies to you only if you are a U.S. Holder. As used herein , the term “U.S. Holder” means a beneficial owner of a Trigger PLUS that is, for U.S. federal income tax purposes: ● a citizen or individual resident of the United States; ● a corporation, or other entity taxable as a corporation, created or organized in or under the laws of the United States, any state thereof or the District of Columbia; or ● an estate or trust the income of which is subject to U.S. federal income taxation regardless of its source. Tax Treatment of the Trigger PLUS Assuming the treatment of the Trigger PLUS as set forth above is respected, the following U.S. federal income tax consequences should result. Tax Basis . A U.S. Holder’s tax basis in the Trigger PLUS should equal the amount paid by the U.S. Holder to acquire the Trigger PLUS . Tax Treatment of Coupon Payments . Any coupon payment on the Trigger PLUS should be taxable as ordinary income to a U.S. Holder at the time received or accrued, in accordance with the U.S. Holder’s regular method of accounting for U.S. federal income tax purposes. Sale , Exchange or Settlement of the Trigger PLUS . Upon a sale, exchange or settlement of the Trigger PLUS, a U.S. Holder should recognize gain or loss equal to the difference between the amount realized on the sale, exchange or settlement and the U.S. Holder’s tax basis in the Trigger PLUS sold, exchanged or settled. For this purpose, the amount realized does not include any coupon paid at settlement and may not include sale proceeds attributable to an accrued coupon, which may be treated as a coupon payment. Subject to the discussion above regarding the possible application of Section 1297 of the Code, any such gain or loss recognized should be long-term capital gain or loss if the U.S. Holder has held the Trigger PLUS for more than one year at the time of the sale, exchange or settlement, and should be short-term capital gain or loss otherwise. The ordinary income treatment of the coupon payments, in conjunction with the capital loss treatment of any loss recognized upon the sale, exchange or settlement of the Trigger PLUS , could result in adverse tax consequences to holders of the Trigger PLUS because the deductibility of capital losses is subject to limitations. Possible Alternative Tax Treatments of an Investment in the Trigger PLUS Due to the absence of authorities that directly address the proper tax treatment of the Trigger PLUS , no assurance can be given that the IRS will accept, or that a court will uphold, the treatment described above. In particular, the IRS could seek to analyze the U.S. federal income tax consequences of owning the Trigger PLUS under Treasury regulations governing contingent payment debt instruments (the “Contingent Debt Regulations”). If the IRS were successful in asserting that the Contingent Debt Regulations applied to the Trigger PLUS, the timing and character

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of income thereon would be significantly affected. Among other things, a U.S. Holder would be required to accrue into income original issue discount on the Trigger PLUS every year at a “comparable yield” determined at the time of their issuance, adjusted upward or downward to reflect the difference, if any, between the actual and the projected amount of any contingent payments on the Trigger PLUS. Furthermore, any gain realized by a U.S. Holder at maturity or upon a sale, exchange or other disposition of the Trigger PLUS would be treated as ordinary income, and any loss realized would be treated as ordinary loss to the extent of the U.S. Holder’s prior accruals of original issue discount and as capital loss thereafter. The risk that financial instruments providing for buffers, triggers or similar downside protection features, such as the Trigger PLUS , would be recharacterized as debt is greater than the risk of recharacterization for comparable financial instruments that do not have such features. Other alternative federal income tax treatments of the Trigger PLUS are possible, which, if applied, could significantly affect the timing and character of the income or loss with respect to the Trigger PLUS. In 2007, the U.S. Treasury Department and the IRS released a notice requesting comments on the U.S. federal income tax treatment of “prepaid forward contracts” and similar instruments. The notice focuses on whether to require holders of “prepaid forward contracts” and similar instruments to accrue income over the term of their investment. It also asks for comments on a number of related topics, including the character of income or loss with respect to these instruments; whether short-term instruments should be subject to any such accrual regime; the relevance of factors such as the exchange–traded status of the instruments and the nature of the underlying property to which the instruments are linked; whether these instruments are or should be subject to the “constructive ownership” rule, which very generally can operate to recharacterize certain long-term capital gain as ordinary income and impose an interest charge; and appropriate transition rules and effective dates. While it is not clear whether instruments such as the Trigger PLUS would be viewed as similar to the prepaid forward contracts described in the notice, any Treasury regulations or other guidance promulgated after consideration of these issues could materially and adversely affect the tax consequences of an investment in the Trigger PLUS, possibly with retroactive effect. U.S. Holders should consult their tax advisers regarding the U.S. federal income tax consequences of an investment in the Trigger PLUS, including possible alternative treatments and the issues presented by this notice. Backup Withholding and Information Reporting Backup withholding may apply in respect of payments on the Trigger PLUS and the payment of proceeds from a sale, exchange or other disposition of the Trigger PLUS , unless a U.S. Holder provides proof of an applicable exemption or a correct taxpayer identification number and otherwise complies with applicable requirements of the backup withholding rules. The amounts withheld under the backup withholding rules are not an additional tax and may be refunded, or credited against the U.S. Holder’s U.S. federal income tax liability, provided that the required information is timely furnished to the IRS. In addition, information returns will be filed with the IRS in connection with payments on the Trigger PLUS and the payment of proceeds from a sale, exchange or other disposition of the Trigger PLUS , unless the U.S. Holder provides proof of an applicable exemption from the information reporting rules. Tax Consequences to Non-U.S. Holders This section applies to you only if you are a Non-U.S. Holder. As used herein, the term “Non-U.S. Holder” means a beneficial owner of a Trigger PLUS that is for U.S. federal income tax purposes: ● an individual who is classified as a nonresident alien; ● a foreign corporation; or ● a foreign estate or trust. The term “Non-U.S. Holder” does not include any of the following holders: ● a holder who is an individual present in the United States for 183 days or more in the taxable year of disposition and who is not otherwise a resident of the United States for U.S. federal income tax purposes; ● certain former citizens or residents of the United States; or ● a holder for whom income or gain in respect of the Trigger PLUS is effectively connected with the conduct of a trade or business in the United States. Such holders should consult their tax advisers regarding the U.S. federal income

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tax consequences of an investment in the Trigger PLUS. Although significant aspects of the tax treatment of each Trigger PLUS are uncertain, we intend to withhold on any coupon paid to a Non-U.S. Holder generally at a rate of 30% or at a reduced rate specified by an applicable income tax treaty under an “other income” or similar provision. We will not be required to pay any additional amounts with respect to amounts withheld. In order to claim an exemption from, or a reduction in, the 30% withholding tax, a Non-U.S. Holder of the Trigger PLUS must comply with certification requirements to establish that it is not a U.S. person and is eligible for such an exemption or reduction under an applicable tax treaty. In addition, as discussed above, if any issuer of Underlying Shares were treated as a USRPHC, certain adverse U.S. federal income tax consequences might apply to a Non-U.S. Holder upon the sale, exchange or settlement of the Trigger PLUS . If you are a Non-U.S. Holder, you should consult your tax adviser regarding the tax treatment of the securities, including the possibility of obtaining a refund of any withholding tax and the certification requirement described above. Section 871(m) Withholding Tax on Dividend Equivalents Section 871(m) of the Code and Treasury regulations promulgated thereunder (“Section 871(m)”) generally impose a 30% (or a lower applicable treaty rate) withholding tax on dividend equivalents paid or deemed paid to Non-U.S. Holders with respect to certain financial instruments linked to U.S. equities or indices that include U.S. equities (each, an “Underlying Security”). Subject to certain exceptions, Section 871(m) generally applies to securities that substantially replicate the economic performance of one or more Underlying Securities, as determined based on tests set forth in the applicable Treasury regulations (a “Specified Security”). However, pursuant to an IRS notice, Section 871(m) will not apply to securities issued before January 1, 2023 that do not have a delta of one with respect to any Underlying Security. Based on our determination that the Trigger PLUS do not have a delta of one with respect to any Underlying Security, our counsel is of the opinion that the Trigger PLUS should not be Specified Securities and, therefore, should not be subject to Section 871(m). Our determination is not binding on the IRS, and the IRS may disagree with this determination. Section 871(m) is complex and its application may depend on your particular circumstances, including whether you enter into other transactions with respect to an Underlying Security. If Section 871(m) withholding is required, we will not be required to pay any additional amounts with respect to the amounts so withheld. You should consult your tax adviser regarding the potential application of Section 871(m) to the Trigger PLUS. U.S. Federal Estate Tax Individual Non-U.S. Holders and entities the property of which is potentially includible in such an individual’s gross estate for U.S. federal estate tax purposes (for example, a trust funded by such an individual and with respect to which the individual has retained certain interests or powers) should note that, absent an applicable treaty exemption, the Trigger PLUS may be treated as U.S.-situs property subject to U.S. federal estate tax. Prospective investors that are non-U.S. individuals, or are entities of the type described above, should consult their tax advisers regarding the U.S. federal estate tax consequences of an investment in the Trigger PLUS . Backup Withholding and Information Reporting Information returns will be filed with the IRS in connection with any coupon payment and may be filed with the IRS in connection with the payment at maturity on the Trigger PLUS and the payment of proceeds from a sale, exchange or other disposition. A Non-U.S. Holder may be subject to backup withholding in respect of amounts paid to the Non-U.S. Holder, unless such Non-U.S. Holder complies with certification procedures to establish that it is not a U.S. person for U.S. federal income tax purposes or otherwise establishes an exemption. The amount of any backup withholding from a payment to a Non-U.S. Holder will be allowed as a credit against the Non-U.S. Holder’s U.S. federal income tax liability and may entitle the Non-U.S. Holder to a refund, provided that the required information is timely furnished to the IRS. FATCA Legislation commonly referred to as “FATCA” generally imposes a withholding tax of 30% on payments to certain non-U.S. entities (including financial intermediaries) with respect to certain financial instruments, unless various U.S. information reporting and due diligence requirements have been satisfied. An intergovernmental agreement between the United States and the non-U.S. entity’s jurisdiction may modify these requirements. FATCA generally applies to certain financial instruments that are treated as paying U.S.-source interest or other U.S.-source “fixed or determinable annual or periodical” income (“FDAP income”).

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Withholding (if applicable) applies to payments of U.S.-source FDAP income and to payments of gross proceeds of the disposition (including upon retirement) of certain financial instruments treated as providing for U.S.-source interest or dividends. Under proposed regulations (the preamble to which specifies that taxpayers are permitted to rely on them pending finalization), no withholding will apply on payments of gross proceeds. While the treatment of the Trigger PLUS is unclear, you should assume that any coupon payment with respect to the Trigger PLUS will be subject to the FATCA rules. If withholding applies to the Trigger PLUS, we will not be required to pay any additional amounts with respect to amounts withheld. Both U.S. and Non-U.S. Holders should consult their tax advisers regarding the potential application of FATCA to the Trigger PLUS. The discussion in the preceding paragraphs, insofar as it purports to describe provisions of U.S. federal income tax laws or legal conclusions with respect thereto, constitutes the full opinion of Davis Polk & Wardwell LLP regarding the material U.S. federal tax consequences of an investment in the Trigger PLUS.
Use of proceeds and hedging: The net proceeds from the sale of the Trigger PLUS will be used by us for general corporate purposes and, in part, in connection with hedging our obligations under the Trigger PLUS through one or more of our affiliates. On or prior to the pricing date, we, through our affiliates or others, will hedge our anticipated exposure in connection with the Trigger PLUS by taking positions in stocks of the underlying indices, futures and/or options contracts on the underlying indices, any component stocks of the underlying indices listed on major securities markets or positions in any other available securities or instruments that we may wish to use in connection with such hedging. Such purchase activity could potentially increase the value of an underlying index on the pricing date, and therefore could increase the respective trigger level, which is the level at or above which such underlying index must close on the valuation date so that investors do not suffer a significant loss on their initial investment in the Trigger PLUS (depending also on the performance of the other underlying indices). In addition, through our affiliates, we are likely to modify our hedge position throughout the term of the Trigger PLUS, including on the valuation date, by purchasing and selling the stocks constituting the underlying indices, futures or options contracts on the underlying indices or its component stocks listed on major securities markets or positions in any other available securities or instruments that we may wish to use in connection with such hedging activities. As a result, these entities may be unwinding or adjusting hedge positions during the term of the Trigger PLUS, and the hedging strategy may involve greater and more frequent adjustments to the hedge as the valuation date approaches. We cannot give any assurance that our hedging activities will not affect the value of an underlying index and, therefore, adversely affect the value of the Trigger PLUS or the payment you will receive at maturity, if any (depending also on the performance of the other underlying indices). For further information on our use of proceeds and hedging, see “Use of Proceeds and Hedging” in the accompanying product supplement for PLUS.
Additional considerations: Client accounts over which Morgan Stanley, Morgan Stanley Wealth Management or any of their respective subsidiaries have investment discretion are not permitted to purchase the Trigger PLUS, either directly or indirectly.
Supplemental information regarding plan of distribution; conflicts of interest: Selected dealers, which may include our affiliates, and their financial advisors will collectively receive from the agent a fixed sales commission of $36.25 for each Trigger PLUS they sell. MS & Co. is an affiliate of MSFL and a wholly owned subsidiary of Morgan Stanley, and it and other affiliates of ours expect to make a profit by selling, structuring and, when applicable, hedging the Trigger PLUS. MS & Co. will conduct this offering in compliance with the requirements of FINRA

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Rule 5121 of the Financial Industry Regulatory Authority, Inc., which is commonly referred to as FINRA, regarding a FINRA member firm’s distribution of the securities of an affiliate and related conflicts of interest. MS & Co. or any of our other affiliates may not make sales in this offering to any discretionary account. See “Plan of Distribution (Conflicts of Interest)” and “Use of Proceeds and Hedging” in the accompanying product supplement for PLUS.
Validity of the Trigger PLUS: In the opinion of Davis Polk & Wardwell LLP, as special counsel to MSFL and Morgan Stanley, when the Trigger PLUS offered by this pricing supplement have been executed and issued by MSFL, authenticated by the trustee pursuant to the MSFL Senior Debt Indenture (as defined in the accompanying prospectus) and delivered against payment as contemplated herein, such Trigger PLUS will be valid and binding obligations of MSFL and the related guarantee will be a valid and binding obligation of Morgan Stanley, enforceable in accordance with their terms, subject to applicable bankruptcy, insolvency and similar laws affecting creditors’ rights generally, concepts of reasonableness and equitable principles of general applicability (including, without limitation, concepts of good faith, fair dealing and the lack of bad faith), provided that such counsel expresses no opinion as to (i) the effect of fraudulent conveyance, fraudulent transfer or similar provision of applicable law on the conclusions expressed above and (ii) any provision of the MSFL Senior Debt Indenture that purports to avoid the effect of fraudulent conveyance, fraudulent transfer or similar provision of applicable law by limiting the amount of Morgan Stanley’s obligation under the related guarantee. This opinion is given as of the date hereof and is limited to the laws of the State of New York, the General Corporation Law of the State of Delaware and the Delaware Limited Liability Company Act. In addition, this opinion is subject to customary assumptions about the trustee’s authorization, execution and delivery of the MSFL Senior Debt Indenture and its authentication of the Trigger PLUS and the validity, binding nature and enforceability of the MSFL Senior Debt Indenture with respect to the trustee, all as stated in the letter of such counsel dated November 16, 2020, which is Exhibit 5-a to the Registration Statement on Form S-3 filed by Morgan Stanley on November 16, 2020.
Where you can find more information: MSFL and Morgan Stanley have filed a registration statement (including a prospectus, as supplemented by the product supplement for PLUS and index supplement) with the Securities and Exchange Commission, or SEC, for the offering to which this communication relates. You should read the prospectus in that registration statement, the product supplement for PLUS, the index supplement and any other documents relating to this offering that MSFL and Morgan Stanley have filed with the SEC for more complete information about MSFL and Morgan Stanley and this offering. You may get these documents without cost by visiting EDGAR on the SEC web site at . www.sec.gov. Alternatively, MSFL, Morgan Stanley, any underwriter or any dealer participating in this offering will arrange to send you the product supplement for PLUS, index supplement and prospectus if you so request by calling toll-free 800-584-6837. You may access these documents on the SEC web site at . www.sec.gov . as follows: Product Supplement for PLUS dated November 16, 2020 Index Supplement dated November 16, 2020 Prospectus dated November 16, 2020 Terms used but not defined in this document are defined in the product supplement for PLUS, in the index supplement or in the prospectus. “Performance Leveraged Upside Securities SM ” and “PLUS SM ” are our service

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marks.

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