MORGAN STANLEY — Capital/Financing Update 2012

Nov 2, 2012

October 2012 Pricing Sheet dated October 31, 2012 relating to Preliminary Terms No. 378 dated October 17, 2012 Registration Statement No. 333-178081 Filed pursuant to Rule 433

STRUCTURED INVESTMENTS

Opportunities in U.S. Equities

PLUS Based on the Value of the Morgan Stanley Mega 30 Index (Price Return) due October 30, 2014

Performance Leveraged Upside Securities SM

PRICING TERMS – OCTOBER 31, 2012 — Issuer:	Morgan Stanley
Maturity date:	October 30, 2014
Underlying index:	Morgan Stanley Mega 30 Index (Price Return)
Aggregate principal amount:	$900,000
Payment at maturity:	If final index value is greater than initial index value,
	$10 + leveraged upside payment
	In no event will the payment at maturity exceed the maximum payment at maturity.
	If final index value is less than or equal to initial index value,
	$10 × index performance factor
	This amount will be less than or equal to the stated principal amount of $10.
Leveraged upside payment:	$10 × leverage factor × index percent increase
Index percent increase:	(final index value – initial index value) / initial index value
Initial index value:	986.37, which is the index closing value on the pricing date
Final index value:	The index closing value on the valuation date
Valuation date:	October 27, 2014, subject to adjustment for non-index business days
Leverage factor:	300%
Index performance factor:	final index value / initial index value
Maximum payment at maturity:	$12.10 per PLUS (121% of the stated principal amount)
Stated principal amount:	$10 per PLUS
Issue price:	$10 per PLUS
Pricing date:	October 31, 2012
Original issue date:	November 5, 2012 (3 business days after the pricing date)
CUSIP:	61755S818
ISIN:	US61755S8180
Listing:	The PLUS will not be listed on any securities exchange.
Agent:	Morgan Stanley & Co. LLC (“MS & Co.”), a wholly-owned subsidiary of Morgan Stanley. See “Supplemental information regarding plan of distribution; conflicts of interest” in the accompanying preliminary terms.
Commissions and issue price:	Price to public	Agent’s commissions (1)	Proceeds to issuer
Per PLUS	$10	$0.225	$9.775
Total	$900,000	$20,250	$879,750

(1) Selected dealers, including Morgan Stanley Smith Barney LLC (an affiliate of the agent), and their financial advisors will collectively receive from the Agent, MS & Co., a fixed sales commission of $0.225 for each PLUS they sell. For additional information, see “Supplemental information regarding plan of distribution; conflicts of interest” in the accompanying preliminary terms and “Plan of Distribution (Conflicts of Interest)” in the accompanying product supplement for PLUS.

The PLUS are not bank deposits and are not insured by the Federal Deposit Insurance Corporation or any other governmental agency, nor are they obligations of, or guaranteed by, a bank.

You should read this document together with the preliminary terms describing the offering and the related product supplement and prospectus, each of which can be accessed via the hyperlinks below.

EFPlaceholder Preliminary Terms No. 378 dated October 17, 2012

EFPlaceholder Product Supplement for PLUS dated August 17, 2012 EFPlaceholder Prospectus dated November 21, 2011

The issuer has filed a registration statement (including a prospectus) with the SEC for the offering to which this communication relates. Before you invest, you should read the prospectus in that registration statement and other documents the issuer has filed with the SEC for more complete information about the issuer and this offering. You may get these documents for free by visiting EDGAR on the SEC Web site at . www.sec.gov. Alternatively, the issuer, any underwriter or any dealer participating in this offering will arrange to send you the prospectus if you request it by calling toll-free 1-800-584-6837.