MILESTONE SCIENTIFIC INC. — Director's Dealing 2007

May 23, 2007

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: MILESTONE SCIENTIFIC INC/NJ (MLSS.OB)
CIK: 0000855683
Period of Report: 2003-03-14

Reporting Person: Fuller Jeffrey (Director)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2007-05-21	Common Stock	M	10000	$0.83	Acquired	10000	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2007-05-21	Options to purchase Common Stock	$.83	M	10000	Disposed	2011-06-19	Common Stock (10000)	Direct
2003-03-14	Options to purchase Common Stock	$1.50	A	6667	Acquired	2008-03-13	Common Stock (6667)	Direct
2005-03-19	Options to purchase Common Stock	$3.27	A	20000	Acquired	2010-03-18	Common Stock (20000)	Direct
2005-11-17	Options to purchase Common Stock	$1.40	A	20000	Acquired	2010-11-16	Common Stock (20000)	Direct
2006-06-20	Options to purchase Common Stock	$.83	A	20000	Acquired	2011-06-19	Common Stock (20000)	Direct

Footnotes

F1: Granted to the Reporting Person on June 20, 2006.

F2: Exercisable as follows: (1) to purchase 10,000 shares of Common Stock beginning on June 20, 2006; and (ii) to purchase an additional 10,000 shares of Common Stock beginning on June 20, 2007.

F3: Not applicable.

F4: Immediate.