MESOBLAST LTD — Capital/Financing Update 2007

Mar 21, 2007

Rule 2.7, 3.10.3, 3.10.4, 3.10.5

Appendix 3B

New issue announcement, application for quotation of additional securities and agreement

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX become ASX's property and may be made public.

Introduced 1/7/96. Origin: Appendix 5. Amended 1/7/98, 1/9/99, 1/7/2000, 30/9/2001, 11/3/2002, 1/1/2003.

Name of entity

Mesoblast Ltd

ABN

68 109 431 870

We (the entity) give ASX the following information.

Part 1 - All issues

You must complete the relevant sections (attach sheets if there is not enough space).

$\mathbbm{I}$ ⁺Class of ⁺securities issued or to be issued

Unlisted Options

330,000 Unlisted Options

$\overline{2}$ Number of ⁺securities issued or to be issued (if known) or maximum number which may be issued

3 Principal terms of the *securities (eg, if options, exercise price and date; if partly paid expiry *securities, the amount outstanding and due dates for payment; if *convertible securities, the conversion price and dates for conversion)

No. of Options - Expiry Date – Exercise Price
10,000	6 Dec 07	\$1.75
50,000	17 Mar 08	\$2.02
10,000	17 May 08	\$1.52
10,000	6 Jun 08	\$1.75
45,000	$01$ Jul $08$	\$1.96
75,000	$01$ Jan $09$	\$1.96
50,000	17 Mar 09	\$2.02
10,000	17 May 09	\$1.52
30,000	01 Jan 10	\$1.96
40,000	01 Jan 11	\$1.96

⁺ See chapter 19 for defined terms.

4	Do the securities rank equally in all respects from the date of allotment with an existing class of quoted *securities? If the additional securities do not rank equally, please state: the date from which they do the extent to which they participate for the next dividend, case of (in- the $\mathbf{a}$ trust. distribution) or interest payment	Options rank equally on exercise to ordinary shares.
	the extent to which they do not rank equally, other than in relation to the next dividend, distribution or interest payment
5	Issue price or consideration	Unlisted Options for Nil
6	Purpose of the issue (If issued as consideration for the acquisition of assets, clearly identify those assets)	Granted to confirm entitlements arising under existing employment/consultancy agreements as provided for in the Executive Share Option Plan
7	Dates of entering *securities into uncertificated holdings or despatch of certificates	22 March 2007
8	Number + class and of all *securities quoted on ASX (including the securities in clause 2 if applicable)	Number *Class 107,648,133 Ordinary

$+$ See chapter 19 for defined terms.

	Number	* Class
οf t class t all and Number "securities not quoted on ASX (including the securities in clause $8,024,667$ 2 if applicable)		Unlisted Options

Dividend policy (in the case of a
trust, distribution policy) on the
increased capital (interests) $10\,$

N/A

Part 2 - Bonus issue or pro rata issue

$\mathbf{1}$	holder security approval Is required?	N/A
12	Is the issue renounceable or non- renounceable?	N/A
13	Ratio in which the "securities will be offered	N/A
14	Class of securities to which the offer relates	N/A
15	determine *Record date to entitlements	N/A
16	Will holdings on different registers (or subregisters) be aggregated for calculating entitlements?	N/A
17	Policy for deciding entitlements in relation to fractions	N/A
18	Names of countries in which the entity has "security holders who will not be sent new issue documents	N/A
	Note: Security holders must be told how their entitlements are to be dealt with.
	Cross reference: rule 7.7.
19	Closing date for of. receipt acceptances or renunciations	N/A

$\overline{\text{+}$ See chapter 19 for defined terms.

20.	Names of any underwriters	N/A
21	Amount of any underwriting fee or commission	N/A
22	Names of any brokers to the issue	N/A
23.	Fee or commission payable to the	N/A
	broker to the issue
24	handling fee Amount of any payable to brokers who lodge	N/A
	acceptances or renunciations on
	behalf of *security holders
25.	If the issue is contingent on	N/A
	"security holders' approval, the
	date of the meeting
26	Date entitlement and acceptance	N/A
	form and prospectus or Product
	Disclosure Statement will be sent to persons entitled
27	If the entity has issued options, and	N/A
	the terms entitle option holders to participate on exercise, the date on
	which notices will be sent to option
	holders
28.	Date rights trading will begin (if	N/A
	applicable)
29	Date rights trading will end (if $N/A$ ) applicable)
30	How do *security holders sell their	N/A
	entitlements $in$ $full$ through a
	broker?
31	How do "security holders sell part	N/A
	of their entitlements through a
	broker and accept for the balance?

$+$ See chapter 19 for defined terms.

$\overline{\mathbf{M}}$ 32 How do *security holders dispose of their entitlements (except by sale through a broker)?

33 *Despatch date

IN/A

$N/A$

Part 3 - Quotation of securities

You need only complete this section if you are applying for quotation of securities

• 34 Type of securities $(iick one)$
• $(a)$ Securities described in Part 1 $\bar{X}$
• $(b)$ All other securities

Example: restricted securities at the end of the escrowed period, partly paid securities that become fully paid, employee incentive share securities when restriction ends, securities issued on expiry or conversion of convertible securities

Entities that have ticked box 34(a)

Additional securities forming a new class of securities

Tick to indicate you are providing the information or documents

• If the "securities are "equity securities, the names of the 20 largest holders of the additional "securities, and the number and percentage of additional "securities held by those holders
• If the *securities are *equity securities, a distribution schedule of the additional 36 *securities setting out the number of holders in the categories $1 - 1,000$ $1,001 - 5,000$ $5,001 - 10,000$ 10,001 - 100,000 100,001 and over

37

A copy of any trust deed for the additional *securities

⁺ See chapter 19 for defined terms.

Entities that have ticked box 34(b)

• 38 Number of securities for which ⁺quotation is sought
• 39 Class of *securities for which quotation is sought
• Do the *securities rank equally in all 40 respects from the date of allotment with an existing ⁺class of quoted *securities?

If the additional securities do not rank equally, please state:

• the date from which they do
• the extent to which they participate for the next dividend. (in the case of a trust, distribution) or interest payment
• the extent to which they do not rank equally, other than in relation to the next dividend, distribution or interest payment
• 41 Reason for request for quotation now

Example: In the case of restricted securities, end of restriction period

(if issued upon conversion of another security, clearly identify that other security)

Number and *class of all *securities 42 quoted on ASX (including the securities in clause 38)

	Number	*Class
i
;

⁺ See chapter 19 for defined terms.

Quotation agreement

• $\mathbf{I}$ *Ouotation of our additional *securities is in ASX's absolute discretion. ASX may quote the *securities on any conditions it decides.
• $\overline{2}$ We warrant the following to ASX.
• The issue of the *securities to be quoted complies with the law and is not for an illegal purpose.
• There is no reason why those *securities should not be granted *quotation.
• An offer of the "securities for sale within 12 months after their issue will not require disclosure under section $707(3)$ or section $1012C(6)$ of the Corporations Act.

Note: An entity may need to obtain appropriate warranties from subscribers for the securities in order to be able to give this warranty

• Section 724 or section 1016E of the Corporations Act does not apply to any applications received by us in relation to any *securities to be quoted and that no-one has any right to return any *securities to be quoted under sections 737, 738 or 1016F of the Corporations Act at the time that we request that the "securities be quoted.
• We warrant that if confirmation is required under section 1017F of the $\bullet$ Corporations Act in relation to the *securities to be quoted, it has been provided at the time that we request that the "securities be quoted.
• If we are a trust, we warrant that no person has the right to return the *securities to be quoted under section 1019B of the Corporations Act at the time that we request that the "securities be quoted.

$\overline{\text{+ See chapter 19}}$ for defined terms.

• $\overline{3}$ We will indemnify ASX to the fullest extent permitted by law in respect of any claim, action or expense arising from or connected with any breach of the warranties in this agreement.
• $\overline{4}$ We give ASX the information and documents required by this form. If any information or document not available now, will give it to ASX before *quotation of the "securities begins. We acknowledge that ASX is relying on the information and documents. We warrant that they are (will be) true and complete.

$\gamma$

Sign here:

...................................... (Company secretary)

Print name:

Kevin Hollingsworth....................................

==

⁺ See chapter 19 for defined terms.