MAYNE PHARMA GROUP LIMITED — Major Shareholding Notification 2009

Nov 10, 2009

form 604 Corporations Law 671B

Notice of change in interests of substantial holder

To: Company Name/Scheme: HalcyGen Pharmaceuticals Limited

ACN/ARSN 76 115 832 963

1. Details of substantial holder[(1)]

name Roger Aston

ACN/ARSN (if applicable) Not applicable

There was a change in the interests of the substantial holder on 29/10/09.

The previous notice was given to the company on 03/07/07.

The previous notice was dated 03/07/07.

2. Previous and present voting power

The total number of votes attached to all the voting shares in the company or voting interests in the scheme that the substantial holder or an associate[(2)] had a relevant interest[(3)] in when last required, and when now required, to give a substantial holding notice to the company or scheme, are as follows:

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Class	of securities	[(4)]	Previous notice	Present notice
Person's votes	Voting	power	[(5)]	Person's votes	Voting	power	[(5)]
Fully	paid	ordinary	shares	9,571,000	12.55%	10,571,000	7.34%

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3. Changes in relevant interests

Particulars of each change in, or change in the nature of, a relevant interest of the substantial holder or an associate in voting securities of the company or scheme, since the substantial holder was last required to give a substantial holding notice to the company or scheme are as follows:

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Date of	Person whose	Nature of change	[(6)]	Consideration given	Class and number of	Person's votes
change	relevant interest	in relation to	securities affected	affected
changed	change	[(7)]
29/10/09	Dr Roger Aston	Purchase of Shares under Second	$200,000	+1,000,000 fully paid	+1,000,000
Placement	ordinary	shares

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4. Present relevant interests

Particulars of each relevant interest of the substantial holder in voting securities after the change are as follows:

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Holder of relevant	Registered holder of	Person entitled to be	Nature of relevant	Class and	Person's votes
interest	securities	registered as holder	[(8)]	interest	[(6)]	number of
securities
Dr Roger Aston	Dr Roger Aston	Dr Roger Aston	Beneficial Owner	5,320,000 FPO	5,320,000
Dr Roger Aston	Newtonmore	Dr Roger Aston	Beneficial Owner	4,251,000 FPO	4,251,000
Biosciences Pty Ltd
Dr Roger Aston	Newtonmore Super	Dr Roger Aston	Beneficial Owner	1,000,000 FPO	1,000,000
Fund

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5. Changes in association

The persons who have become associates[(2)] of, ceased to be associates of, or have change the nature of their association[(9)] with, the substantial holder in relation to voting interests in the company or scheme are as follows:

Name and ACN/ARSN (if applicable) Nature of association

902882

604 GUIDE 2/3 July 2000

6. Addresses

The addresses of persons named in this form are as follows: Name Address Dr Roger Aston Victoria Signature print name Dr Roger Aston capacity Self sign here date 5 November 2009

DIRECTIONS

(1) If there are a number of substantial holders with similar or related relevant interests (eg a corporation and its related corporations, or the manager and trustee of an equity trust), the names could be included in an annexure to the form. If the relevant interests of a group of persons are essentially similar, they may be referred to throughout the form as a specifically named group if the membership of each group, with the names and addresses of members is clearly set out in paragraph 6 of the form.

• (2) See the definition of "associate" in section 9 of the Corporations Law.

• (3) See the definition of "relevant interest" in sections 608 and 671B(7) of the Corporations Law.

• (4) The voting shares of a company constitute one class unless divided into separate classes.

• (5) The person's votes divided by the total votes in the body corporate or scheme multiplied by 100.

• (6) Include details of:

  • (a) any relevant agreement or other circumstance because of which the change in relevant interest occurred. If subsection 671B(4) applies, a copy of any document setting out the terms of any relevant agreement, and a statement by the person giving full and accurate details of any contract, scheme or arrangement, must accompany this form, together with a written statement certifying this contract, scheme or arrangement; and

  • (b) any qualification of the power of a person to exercise, control the exercise of, or influence the exercise of the voting powers or disposal of the securities to which the relevant interest relates (indicating clearly the particular securities to which the qualification applies).

902882

604 GUIDE 3/3 July 2000

See the definition of "relevant agreement" in section 9 of the Corporations Law.

(7) Details of the consideration must include any and all benefits, money and other, that any person from whom a relevant interest was acquired has, or may, become entitled to receive in relation to that acquisition. Details must be included even if the benefit is conditional on the happening or not of a contingency. Details must be included of any benefit paid on behalf of the substantial holder or its associate in relation to the acquisitions, even if they are not paid directly to the person from whom the relevant interest was acquired.

(8) If the substantial holder is unable to determine the identity of the person (eg if the relevant interest arises because of an option) write "unknown".

(9) Give details, if appropriate, of the present association and any change in that association since the last substantial holding notice.

902882