MADRIGAL PHARMACEUTICALS, INC. — Director's Dealing 2012

Nov 15, 2012

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: SYNTA PHARMACEUTICALS CORP (SNTA)
CIK: 0001157601
Period of Report: 2012-11-12

Reporting Person: Kovner Bruce (Director, 10% Owner)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2012-11-12	Common Stock	P	27200	$6.8915	Acquired	937200	Indirect
2012-11-14	Common Stock	P	10500	$6.9532	Acquired	947700	Indirect

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	7096852	Direct
Common Stock	125000	Indirect
Common Stock	125000	Indirect
Common Stock	125000	Indirect
Common Stock	125000	Indirect
Common Stock	475000	Indirect
Common Stock	475000	Indirect
Common Stock	475000	Indirect
Common Stock	475000	Indirect
Common Stock	7761716	Indirect

Footnotes

F1: The shares were purchased in multiple transactions at prices ranging from $6.86 to $6.96 per share. The price reported above is the weighted average purchase price. The Reporting Person hereby undertakes to provide upon request to the staff of the SEC, the Issuer or a security holder of the Issuer, full information regarding the number of shares purchased at each separate price within the range set forth above.

F2: Includes 910,000 shares of Common Stock reported incorrectly on a Form 4 filed on July 2, 2012 as directly owned by the Reporting Person. See Notes 3 and 5.

F3: These shares are owned directly by KFO Holdings LLC ("KFO") and indirectly by the Reporting Person as the sole member of KFO.

F4: The shares were purchased in multiple transactions at prices ranging from $6.92 to $6.98 per share. The price reported above is the weighted average purchase price. The Reporting Person hereby undertakes to provide upon request to the staff of the SEC, the Issuer or a security holder of the Issuer, full information regarding the number of shares purchased at each separate price within the range set forth above.

F5: Excludes 910,000 shares of Common Stock previously reported incorrectly on a Form 4 filed July 2, 2012 as directly owned by the Reporting Person that are directly owned by KFO Holdings LLC and indirectly owned by the Reporting Person. See Notes 2 and 3.

F6: These shares are owned directly by CxSynta LLC and indirectly by the Reporting Person as chairman and sole shareholder of Caxton Corporation, the managing member of CxSynta LLC. The Reporting Person disclaims beneficial ownership of these shares except to the extent of his pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of the beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose.