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Lyra Therapeutics, Inc. Director's Dealing 2020

May 2, 2020

35183_dirs_2020-05-01_370735ca-2876-4546-9303-783916f14338.zip

Director's Dealing

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SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Lyra Therapeutics, Inc. (LYRA)
CIK: 0001327273
Period of Report: 2020-04-30

Reporting Person: PERCEPTIVE ADVISORS LLC (Director, 10% Owner)
Reporting Person: EDELMAN JOSEPH (Director, 10% Owner)

Derivative Transactions

Date Security Exercise Price Code Shares A/D Expiration Underlying Ownership
2020-04-30 Stock Option $16.00 A 14500 Acquired 2030-04-29 Common Stock (14500) Indirect
2020-04-30 Stock Option $16.00 A 14500 Acquired 2030-04-29 Common Stock (14500) Indirect

Footnotes

F1: This option vests and becomes exercisable in 36 equal monthly installments beginning May 30, 2020.

F2: Consists of options to purchase shares of the Issuer's common stock awarded to Konstantin Poukalov in connection with his role as a member of the Issuer's Board of Directors. Mr. Poukalov is affiliated with Perceptive Advisors, LLC (the "Advisor"). The Advisor may be deemed to have an indirect pecuniary interest in the options to purchase common stock of the Issuer reported herein because the Advisor has the right to receive the director compensation provided in respect of Mr. Poukalov's board service through a partial management fee offset.

F3: Consists of options to purchase shares of the Issuer's common stock awarded to Michael Altman in connection with his role as a member of the Issuer's Board of Directors. Mr. Altman is affiliated with the Advisor. The Advisor may be deemed to have an indirect pecuniary interest in the options to purchase common stock of the Issuer reported herein because the Advisor has the right to receive the director compensation provided in respect of Mr. Altman's board service through a partial management fee offset.

F4: Joseph Edelman is the managing member of the Advisor. Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of the securities reported on this form, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes.