Lobe Sciences Ltd. — Proxy Solicitation & Information Statement 2025

Feb 18, 2025

LOBE SCIENCES LTD.
1771 Robson Street #1614
Vancouver, BC, V6G 3B7

NOTICE OF ANNUAL GENERAL MEETING

TO THE SHAREHOLDERS:

NOTICE IS HEREBY GIVEN that the annual general meeting (the “Meeting”) of Lobe Sciences Ltd. (the “Company”) will be held virtually, on March 20, 2025, beginning at the hour of 11:00 a.m. (Vancouver time) for the following purposes:

1. to set the number of directors of the Company at seven and to elect Dr. Fred Sancilio PhD, Harry Jacobson M.D. Wesley Ramjeet, CPA, and Charles F. Goulburn directors of the Company to hold office for three year terms, or until their earlier resignation or such time as their successors are duly elected or appointed in accordance with the Company’s constating documents;
2. to approve the updated articles and bylaws as presented;
3. to appoint Davidson & Company LLP, as the auditors of the Company for the fiscal year ending August 31, 2025 at remuneration to be fixed by the board of directors of the Company (the “Board”);
4. to place before the Meeting the audited financial statements of the Company for the fiscal year ended August 31, 2025, and the accompanying report of the auditors thereon; and
5. to transact such further or other business as may properly come before the Meeting and any adjournment or postponement thereof.

The management information circular (the “Information Circular”) accompanying this notice of Meeting (the “Notice of Meeting”) provides additional information relating to the matters to be dealt with at the Meeting and is supplemental to, and expressly made a part of, this Notice of Meeting.

The Board has fixed February 3, 2025 as the record date for the determination of shareholders entitled to notice of and to vote at the Meeting and at any adjournment or postponement thereof. Each registered shareholder at the close of business on that date is entitled to such notice and to vote at the Meeting in the circumstances set out in the Information Circular.

If you are a registered shareholder of the Company and unable to attend the Meeting, please complete, date and sign the accompanying form of proxy and deposit it with the Company’s transfer agent, Marrelli Trust Company Limited, 620-1111 Melville St., Vancouver, BC, V6E 3V6, at least 48 hours (excluding Saturdays, Sundays and holidays recognized in the Province of British Columbia) before the time and date of the Meeting or any adjournment or postponement thereof.

If you are a non-registered shareholder of the Company and received this Notice of Meeting and accompanying materials through a broker, a financial institution, a participant, or a trustee or administrator of a self-administered retirement savings plan, retirement income fund, education savings plan or other similar self-administered savings or investment plan registered under the Income Tax Act (Canada), or a nominee of any of the foregoing that holds your securities on your behalf (each, an “Intermediary”), please complete and return the materials in accordance with the instructions provided to you by your Intermediary.

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DATED at Vancouver, British Columbia, this 1st day of February, 2025.

By Order of the Board of Directors of

LOBE SCIENCES LTD.

“Dr. Fred Sancilio”

Dr. Fred Sancilio

Executive Chairman and Chief Executive Officer