LEXICON PHARMACEUTICALS, INC. — Director's Dealing 2020

Dec 17, 2020

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: LEXICON PHARMACEUTICALS, INC. (LXRX)
CIK: 0001062822
Period of Report: 2020-12-16

Reporting Person: Invus Public Equities, L.P. (Director, 10% Owner)
Reporting Person: Artal Treasury Ltd (Director, 10% Owner)
Reporting Person: Invus, L.P. (Director, 10% Owner)
Reporting Person: Invus Public Equities Advisors, LLC (Director, 10% Owner)
Reporting Person: Invus Advisors, L.L.C. (Director, 10% Owner)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2020-12-16	Common Stock	P	10937500	$3.20	Acquired	32259461	Indirect

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	3516214	Indirect
Common Stock	35402689	Indirect

Footnotes

F1: On December 11, 2020, Artal International S.C.A. entered into a subscription agreement with the Issuer and other parties thereto, pursuant to which Artal International S.C.A. agreed to purchase 10,937,500 shares of Class A common stock of the Issuer at a price of $3.20 per share. The purchase closed on December 16, 2020.

F2: These securities are directly held by Artal International S.C.A.

F3: These securities are directly held by Invus Public Equities, L.P.

F4: These securities are directly held by Invus, L.P.

F5: Invus Public Equities Advisors, LLC is the general partner of Invus Public Equities, L.P., and Invus Advisors, L.L.C. is the general partner of Invus, L.P. Artal Treasury Limited is the managing member of Invus Public Equities Advisors, LLC. Artal International S.C.A. is the managing member of Invus Advisors, L.L.C. and, through its Geneva branch, is the sole stockholder of Artal Treasury Limited. The managing partner of Artal International S.C.A. is Artal International Management S.A. The parent company of Artal International Management S.A. is Artal Group S.A. The parent company of Artal Group S.A. is Westend S.A. The majority stockholder of Westend S.A. is Stichting Administratiekantoor Westend (the "Stichting"). Mr. Pascal Minne is the sole member of the board of the Stichting.

F6: Each of the Reporting Persons (other than to the extent it directly holds securities reported herein) disclaims beneficial ownership of the securities held by the other Reporting Persons, except to the extent of such Reporting Person's pecuniary interest therein, and, pursuant to Rule 16a-1(a)(4) under the Exchange Act, each of the Reporting Persons (other than to the extent it directly holds securities reported herein) states that the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 of the Exchange Act or for any other purpose.

F7: Due to the limitations of the electronic filing system certain Reporting Persons are filing a separate Form 4.