LEXICON PHARMACEUTICALS, INC. — Director's Dealing 2014

Nov 26, 2014

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: LEXICON PHARMACEUTICALS, INC./DE (LXRX)
CIK: 0001062822
Period of Report: 2014-11-26

Reporting Person: Artal International S.C.A. (Director, 10% Owner)
Reporting Person: Minne Pascal (Director, 10% Owner)
Reporting Person: Invus, L.P. (Director, 10% Owner)
Reporting Person: Invus Public Equities, L.P. (Director, 10% Owner)
Reporting Person: Artal International Management S.A. (Director, 10% Owner)
Reporting Person: Artal Group S.A. (Director, 10% Owner)
Reporting Person: Westend S.A. (Director, 10% Owner)
Reporting Person: Stichting Administratiekantoor Westend (Director, 10% Owner)
Reporting Person: Invus Advisors, L.L.C. (Director, 10% Owner)
Reporting Person: Invus Public Equities Advisors, LLC (Director, 10% Owner)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2014-11-26	Common Stock	P	149253731	$1.005	Acquired	149253731	Indirect

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	247818843	Indirect
Common Stock	5553292	Indirect

Footnotes

F1: These securities are directly held by Artal International S.C.A.

F2: These securities are directly held by Invus, L.P.

F3: These securities are directly held by Invus Public Equities, L.P.

F4: Invus Advisors, L.L.C. is the general partner of Invus, L.P., and Invus Public Equities Advisors, LLC is the general partner of Invus Public Equities, L.P. Artal International S.C.A. is the managing member of each of Invus Advisors, L.L.C. and Invus Public Equities Advisors, LLC. The managing partner of Artal International S.C.A. is Artal International Management S.A., both of which are wholly owned subsidiaries of Artal Group S.A., which is a wholly owned subsidiary of Westend S.A., which is a wholly owned subsidiary of Stichting Administratiekantoor Westend (the "Stichting"). Mr. Pascal Minne is the sole member of the board of the Stichting.

F5: Each of the Reporting Persons (other than to the extent it directly holds securities reported herein) disclaims beneficial ownership of the securities held by the other Reporting Persons, except to the extent of such Reporting Person's pecuniary interest therein, and, pursuant to Rule 16a-1(a)(4) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), each of the Reporting Persons (other than to the extent it directly holds securities reported herein) states that the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of all of the reported securities for purposes of Section 16 or for any other purpose.