LEXICON PHARMACEUTICALS, INC. — Director's Dealing 2011

Mar 25, 2011

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: LEXICON PHARMACEUTICALS, INC./DE (LXRX)
CIK: 0001062822
Period of Report: 2011-03-23

Reporting Person: Lapuerta Pablo (SVP, Clin Dev and CMO)

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2011-03-23	Stock Option (Right to Buy)	$1.72	A	200000	Acquired	2021-03-23	Common Stock (200000)	Direct

Footnotes

F1: Option vests with respect to 25% of the shares subject to the option on the first anniversary of grant (3/23/2012) and vests 1/48th per month for each month of service therafter.