Lepu Biopharma Co., Ltd. — Proxy Solicitation & Information Statement 2025

Jun 6, 2025

东普主钧

LEPU BIOPHARMA

LEPU BIOPHARMA CO., LTD.

樂普生物科技股份有限公司

(A joint stock company incorporated in the People's Republic of China with limited liability)

(Stock Code: 2157)

Proxy Form for the Annual General Meeting to be held on June 27 2025

I/We $^{(Note1)}$

of

being the registered holder(s) of $^{(Note2)}$

shares of RMB1.00 each in the share capital of Lepu Biopharma Co., Ltd. (the "Company") HEREBY APPOINT THE CHAIRMAN OF

THE AGM or $^{(Note3)}$

of

as my/our proxy to attend and act for me/us at the annual general meeting of the Company to be held at 5/F, United Centre, 95 Queensway, Admiralty, Hong Kong on Friday, June 27, 2025 at 10:30 a.m. (the "AGM") (and any adjournment thereof) for the purposes of considering and, if thought fit, passing the resolutions as set out in the notice convening the AGM and at the AGM (and at any adjournment thereof) to vote for me/us and in my/our name(s) in respect of the resolutions as indicated below $^{(Note4)}$. Unless otherwise indicated, capitalised terms used herein shall have the same meanings as ascribed to them in the circular dated June 6, 2025 issued by the Company (the "Circular").

ORDINARY RESOLUTIONS		FOR $^{(Note4)}$	AGAINST $^{(Note4)}$	ABSTAIN $^{(Note4)}$
1.	To consider and approve the resolution on the report of the Board of Directors of the Company for the year 2024.
2.	To consider and approve the resolution on the report of the Board of Supervisors of the Company for the year 2024.
3.	To consider and approve the resolution on the annual report of the Group for the year 2024.
4.	To consider and approve the resolution on the financial accounts report of the Group for the year 2024.
5.	To consider and approve the resolution on the financial budget of the Group for the year 2025.
6.	To consider and approve the resolution on the annual profit distribution plan of the Company for the year 2024.
7.	To consider and approve the re-appointment of Ernst & Young as the auditor of the Company for 2025, for a term commencing from the date of approval at the AGM until the conclusion of the 2025 annual general meeting of the Company, and authorize the Board to determine the specific matters in relation to such re-appointment, including but not limited to their remunerations.
8.	To consider and approve the proposed appointment of non-executive director.
SPECIAL RESOLUTION
9.	To consider and approve the resolution on the grant of a general mandate to the Board to issue, allot and deal with the additional Shares.

Date:

Signature(s) $^{(Note5)}$:

Notes:

1. Please insert full name(s) and address(es) as shown in the register of members of the Company in BLOCK CAPITALS.
2. Please insert the number of shares registered in your name(s) and type of shares (Domestic shares or H shares) to which this proxy form relates. If no number of shares is inserted, this proxy form will be deemed to relate to all shares registered in your name(s).
3. If any proxy other than the Chairman of the AGM is preferred, strike out the words "THE CHAIRMAN OF THE AGM or" and insert the name and address of the proxy desired in the space provided. A shareholder entitled to attend and vote at the AGM may appoint one or more proxies to attend and vote in his stead. A proxy need not be a shareholder of the Company but must attend the AGM in person to represent you. ANY ALTERATION MADE TO THIS PROXY FORM MUST BE INITIALLED BY THE PERSON(S) WHO SIGNS IT.
4. IMPORTANT: IF YOU WISH TO VOTE FOR A RESOLUTION, TICK (,) IN THE RELEVANT BOX BELOW THE BOX MARKED "FOR". IF YOU WISH TO VOTE AGAINST A RESOLUTION, TICK (,) IN THE RELEVANT BOX BELOW THE BOX MARKED "AGAINST". If no direction is given, your proxy may vote or abstain at his discretion. Your proxy will also be entitled to vote or abstain at his discretion on any resolution properly put to the AGM other than that referred to in the notice convening the AGM.
5. This proxy form must be signed by you or your attorney duly authorized in writing. In case of a corporation, the same must be executed either under its common seal or under the hand of its director(s) or duly authorized attorney. If the proxy form is signed by an attorney of the shareholder, the power of attorney authorizing that attorney to sign or other authorization document must be notarized.
6. In case of joint holders of any shares, any one of such joint holders may vote at the AGM, either in person or by proxy, in respect of such shares as if he is solely entitled thereto. However, if more than one of such joint holders are present at the AGM, in person or by proxy, the vote of the joint holder whose name stands first on the register of members, whether in person or by proxy, will be accepted to the exclusion of the votes of other joint holder(s).
7. In order to be valid, the instrument appointing a proxy together with the power of attorney or other authority, if any, under which it is signed, or a notarially certified copy of such power of attorney or authority, must be completed and returned to the Company's head office and principal place of business in the PRC, at No. 651, Lianheng Road, Minhang District, Shanghai, the PRC (for holders of Domestic Shares) or the H Share Registrar of the Company in Hong Kong, Computershare Hong Kong Investor Services Limited, at 17M Floor, Hopewell Centre, 183 Queen's Road East, Wanchai, Hong Kong (for holders of H shares), not less than 24 hours before the time fixed for holding the AGM (i.e. before 10:30 a.m. on Thursday, June 26, 2025) or any adjourned meeting thereof. Completion and return of the form of proxy will not preclude a shareholder from attending and voting at the AGM or any adjourned meeting thereof should he/she so wish.
8. Shareholders or their proxies attending the AGM (and any adjournment thereof) shall produce their identity documents.