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Khiron Life Sciences Corp. Board/Management Information 2022

Aug 27, 2022

47040_rns_2022-08-26_aa1ef955-642e-432c-958f-e445eac76eff.pdf

Board/Management Information

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FORM 51-102F3

MATERIAL CHANGE REPORT

Item 1. Name and Address of Company Khiron Life Sciences Corp. (the “ Company ”) 2300 – 500 Burrard Street Vancouver, BC V6C 2B5 Item 2. Date of Material Change July 18, 2022 Item 3. News Release A press release was issued through CNW on July 18, 2022 and subsequently filed on SEDAR. Item 4. Summary of Material Change

The Company announced the appointment of Helen Bellwood as Interim CFO, effective July 18, 2022.

Item 5. Full Description of Material Change 5.1 Full Description of Material Change The Company announced the appointment of Helen Bellwood as Interim CFO, effective July 18, 2022.

5.2 Disclosure for Restructuring Transactions Not Applicable.

Item 6. Reliance on Subsection 7.1(2) or (3) of National Instrument 51-102 – Continuous Disclosure Obligations Not Applicable. Item 7. Omitted Information

None.

Item 8. Executive Officer Knowledgeable of Material Change

Alvaro Torres Chief Executive Officer (647) 556-5750