Jazz Pharmaceuticals plc — Director's Dealing 2025

Dec 4, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: Jazz Pharmaceuticals plc (JAZZ)
CIK: 0001232524
Period of Report: 2025-12-02

Reporting Person: O'Keefe Kenneth W (Director)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-12-02	Ordinary Shares	F	603	$173.07	Disposed	25811	Direct

Holdings (Non-Derivative)

Security	Shares	Ownership
Ordinary Shares	4445	Indirect

Footnotes

F1: Shares sold to satisfy tax obligations arising out of the vesting of previously granted restricted stock units.

F2: Reflects the cancellation for no value of 2,258 RSU shares on December 1, 2025.

F3: Shares are held for the benefit of The Kenneth W. O'Keefe Trust U/A/D 2/12/1997, of which the reporting person is both trustee and beneficiary.