IsoEnergy Ltd. — AGM Information 2021

May 12, 2021

ISOENERGY LTD.

NOTICE OF ANNUAL AND SPECIAL MEETING OF SHAREHOLDERS

NOTICE IS HEREBY GIVEN that the annual and special meeting (the “ Meeting ”) of shareholders of IsoEnergy Ltd. (the “ Corporation ” or “ IsoEnergy ”) will be held on Tuesday, June 8, 2021 at 2:30 p.m. (Vancouver time) at the offices of NexGen Energy Ltd., located at 3150 - 1021 West Hasting Street, Vancouver, BC V6E 0C3 for the following purposes:

1. to receive the audited consolidated financial statements of the Corporation for the period ended December 31, 2020 together with the report of the independent auditor thereon;

2. to set the number of directors at five (5) and to elect the directors of the Corporation for the ensuing year;

3. to appoint KPMG LLP as independent auditor of the Corporation for the 2021 fiscal year and to authorize the directors to fix their remuneration;

4. to consider and, if deemed appropriate, to pass, with or without variation, an ordinary resolution reapproving the stock option plan of the Corporation; and

5. to transact such other business as may properly come before the Meeting or any adjournment or postponement thereof.

Shareholders will also be able to access the Meeting by teleconference using the details below.

The nature of the business to be transacted at the Meeting is described in further detail in the accompanying management information circular, which is deemed to form part of this Notice of Meeting. Please read the management information circular carefully before you vote on the matters being transacted at the Meeting.

Your vote is important regardless of the number of IsoEnergy shares you own. All registered shareholders are entitled to attend and vote at the Meeting in person or by proxy; however, the Corporation’s board of directors is requesting that due to the current COVID-19 pandemic that all shareholders vote their shares by proxy in advance of the Meeting and not attend the Meeting in person. Registered IsoEnergy shareholders are requested to complete, date, sign and return the enclosed form of proxy or, alternatively, to vote by telephone, or over the Internet, in each case in accordance with the enclosed instructions. To be used at the Meeting, the completed proxy form must be deposited at the office of Computershare Investor Services Inc., by fax within North America at 1-866-249-7775, outside North America at (416) 2639524, or by mail to the 8th Floor, 100 University Avenue, Toronto, Ontario, M5J 2Y1, not later than 2:30 p.m. (Vancouver time) on June 4, 2021 or, if the Meeting is adjourned or postponed, not later than 48 hours (excluding Saturdays, Sundays and statutory holidays in the Province of British Columbia) prior to the time set for the adjourned or postponed meeting.

Non-registered IsoEnergy shareholders who receive these materials through their broker or other intermediary should complete and send the form of proxy or voting instruction form in accordance with the instructions provided by their broker or intermediary.

Late proxies may be accepted or rejected by the Chair of the Meeting in his or her discretion.

Shareholders that wish to access the Meeting by teleconference can do so by dialing the number below. For international dial-in details please contact the Corporation at info@isoenergy.ca.

North American Toll Free : 888-390-0546

Conference ID : 74029229

DATED at Vancouver, British Columbia, this 4th day of May, 2021.

BY ORDER OF THE BOARD

“Tim Gabruch” Tim Gabruch President & Chief Executive Officer

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