IONIS PHARMACEUTICALS INC — Director's Dealing 2019

Dec 20, 2019

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: IONIS PHARMACEUTICALS INC (IONS)
CIK: 0000874015
Period of Report: 2019-12-20

Reporting Person: HOUGEN ELIZABETH L (SVP, Finance & CFO)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2019-12-20	Common Stock	M	7196	$10.82	Acquired	27251	Direct
2019-12-20	Common Stock	F	4215	$61.52	Disposed	23036	Direct
2019-12-20	Common Stock	M	3438	$10.82	Acquired	26474	Direct
2019-12-20	Common Stock	F	2014	$61.52	Disposed	24460	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2019-12-20	Employee Stock Option (right to buy)	$10.82	M	7196	Disposed	2020-01-01	Common Stock (7196)	Direct
2019-12-20	Employee Stock Option (right to buy)	$10.82	M	3438	Disposed	2020-01-01	Common Stock (3438)	Direct

Footnotes

F1: Acquired as a result of exercising a stock option in accordance with the Amendment to Outstanding Options Agreement dated November 9, 2015 between the reporting person and issuer ("Agreement"). The purchase and partial sale reported on this Form 4 was effective pursuant to the Agreement.

F2: Shares sold to cover the option cost and tax withholding obligations pursuant to the Agreement.

F3: Represents the date on which the options are fully exercisable pursuant to the vesting schedule of the grant.