IONIS PHARMACEUTICALS INC — Director's Dealing 2018

Apr 19, 2018

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: AKCEA THERAPEUTICS, INC. (AKCA)
CIK: 0001662524
Period of Report: 2018-04-17

Reporting Person: IONIS PHARMACEUTICALS INC (10% Owner)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2018-04-17	Common Stock	J	8000000	—	Acquired	53447879	Direct
2018-04-17	Common Stock	P	10666666	$18.75	Acquired	64114545	Direct

Footnotes

F1: Shares issued in satisfaction of the Issuer's obligations to the Reporting Person pursuant to that certain License Agreement, dated March 14, 2018, between the Issuer and the Reporting Person.

F2: Shares purchased pursuant to that certain Stock Purchase Agreement, dated March 14, 2018, between the Issuer and the Reporting Person.