Ion Beam Applications, SA

Major Shareholding Notification • Feb 18, 2021

IBA – TRANSPARENCY NOTIFICATION

(Article 14, paragraph 1 of the law of 2 May 2007 on the disclosure of major holdings)

Louvain-la-Neuve, Belgium, February 18th , 2021, 07:30 pm

Summary of the notification

IBA (Ion Beam Application), the world's leading provider of proton therapy solutions for the treatment of cancer, announces that it has to issue a transparency notification, in accordance with Article 14, al. 1 of the Transparency Law of May 2, 2007 on disclosure of major holdings, further to the notification received on February 16, 2021.

In its notification, BlackRock, Inc. has notified, that following an acquisition of voting rights, its total holding in IBA SA has crossed upwards the 1% threshold.

Content of the notification

• Reason for the notification: Acquisition or disposal of voting securities or voting rights
• Notification by : A parent undertaking or a controlling person
• Persons subject to the notification requirement:

BlackRock Inc., 55 East 52nd Street, New York, NY, 10055, U.S.A. BlackRock (Netherlands) B.V, Rembrandt Tower, 17th floor, Amstelplein, Amsterdam, Netherlands

BlackRock Advisors (UK) Limited, 12 Throgmorton Avenue, London, EC2N 2DL, U.K. BlackRock Asset Management Canada Limited, 161 Bay Street,, Suite 2500, Toronto, Ontario,

M5J 2S1, Canada

BlackRock Fund Advisors, 400 Howard Street, San Francisco, CA, 94105, U.S.A.

BlackRock Institutional Trust Company, National Association, 400 Howard Street, San Francisco, CA, 94105, U.S.A.

BlackRock Investment Management, LLC, 1 University Square Drive, Princeton, NJ, 8540,, U.S.A.

• Date on which the threshold is crossed: 12/02/2021
• Threshold crossed (in %): 1%
• Denominator: 38.254.747
• Notified details:

Press release 18/02/2021

Press Release Regulated information

A) Voting rights	Previous notification # of voting rights	After the transaction
		# of voting rights		% of voting rights
Holders of voting rights		Linked to securities	Not linked to the securities	Linked to securities	Not linked to the securities
BlackRock, Inc.	0	0		0,00%
BlackRock (Netherlands) B.V.	2.489	2.489		0.01%
BlackRock Advisors (UK) Limited	18.401	25.101		0.07%
BlackRock Asset Management Canada Limited	5.768	5.768		0.02%
BlackRock Fund Advisors	226,906	228.263		0,60%
BlackRock Institutional Trust Company, National Association	108.083	120.941		0,32%
BlackRock Investment Management, LLC	28	28		0.00%
Subtotal	361.675	382.590		1.00%
TO TAL		382.590	0	1,00%	0,00%

B) Equivalent financial instruments	After the transaction
Holders of equivalent financial instruments	Type of financial instrument	Expiration date	Exercise period or date	# of voting rights that may be acquired if the instrument is exercised	% of voting rights	Settlement
BlackRock Advisors (UK) Limited	Securities Lent			9.946	0,03%	physical
BlackRock Fund Advisors	Securities Lent			80	0.00%	physical
BlackRock Institutional Trust Company, National Association	Securities Lent			12.482	0,03%	physical
BlackRock Investment Management, ELC	Securities Lent			516	0,00%	physical	+
	TOTAL			23.024	0.06%

TOTAL (A & B)		# of voting rights % of voting rights
	CALCULATE	405.614	1,06%

• Full chain of controlled undertakings through which the holding is effectively held

BlackRock, Inc. Trident Merger, LLC BlackRock Investment Management, LLC

BlackRock, Inc. BlackRock Holdco 2, Inc. BlackRock Financial Management, Inc.

Press release 18/02/2021

2

BlackRock Holdco 4, LLC BlackRock Holdco 6, LLC BlackRock Delaware Holdings Inc. BlackRock Institutional Trust Company, National Association

BlackRock, Inc. BlackRock Holdco 2, Inc. BlackRock Financial Management, Inc. BlackRock Holdco 4, LLC BlackRock Holdco 6, LLC BlackRock Delaware Holdings Inc. BlackRock Fund Advisors

BlackRock, Inc. BlackRock Holdco 2, Inc. BlackRock Financial Management, Inc. BlackRock International Holdings, Inc. BR Jersey International Holdings L.P. BlackRock Holdco 3, LLC BlackRock Canada Holdings LP BlackRock Canada Holdings ULC BlackRock Asset Management Canada Limited

BlackRock, Inc. BlackRock Holdco 2, Inc. BlackRock Financial Management, Inc. BlackRock International Holdings, Inc. BR Jersey International Holdings L.P. BlackRock Holdco 3, LLC BlackRock Cayman 1 LP BlackRock Cayman West Bay Finco Limited BlackRock Cayman West Bay IV Limited BlackRock Group Limited BlackRock Finance Europe Limited BlackRock Advisors (UK) Limited

BlackRock, Inc. BlackRock Holdco 2, Inc. BlackRock Financial Management, Inc. BlackRock International Holdings, Inc. BR Jersey International Holdings L.P. BlackRock Holdco 3, LLC BlackRock Cayman 1 LP

Press release 18/02/2021

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BlackRock Cayman West Bay Finco Limited BlackRock Cayman West Bay IV Limited BlackRock Group Limited BlackRock Finance Europe Limited BlackRock (Netherlands) B.V.

• Additional Information

The disclosure obligation arose due to voting rights attached to shares for BlackRock, Inc. going above 1%.

For further information, please contact:

IBA

Valérie Van Impe Paralegal +32 10 203 180 legal@iba-group.com

About IBA

IBA (Ion Beam Applications) is a global medical technology company focused on bringing integrated and innovative solutions for the diagnosis and treatment of cancer. The company is the worldwide technology leader in the field of proton therapy, considered to be the most advanced form of radiation therapy available today. IBA's proton therapy solutions are flexible and adaptable, allowing customers to choose from universal full-scale proton therapy centers as well as compact, single room solutions. In addition, IBA also has a radiation dosimetry business and develops particle accelerators for the medical world and industry. Headquartered in Belgium and employing about 1,500 people worldwide, IBA has installed systems across the world.

IBA is listed on the pan-European stock exchange NYSE EURONEXT (IBA: Reuters IBAB.BR and Bloomberg IBAB.BB). More information can be found at: www.iba-worldwide.com