INVION LIMITED — Capital/Financing Update 2011

Sep 4, 2011

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5 September 2011

Dear Option holder,

Non-renounceable Rights Issue- Option holder participation

CBio Limited (ASX: CBZ ) today lodged with the ASX a Prospectus for a non-renounceable rights issue to raise up to $10.8 million.

Copies of the Prospectus are available on the ASX website (www.asx.com.au) as well as on the Company’s website (www.cbio.com.au).

Investors who hold options in CBio but do not hold shares may only participate in the offer if some or all of their options are exercised prior to the Record Date, being 13 September 2011, and they are recorded on the share register as shareholders.

Should you wish to exercise your options please contact the Company Secretary on (07) 3841 4844.

Yours sincerely

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STEPHEN JONES Executive Chairman