INSMED Inc — Director's Dealing 2025

Jun 18, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: INSMED Inc (INSM)
CIK: 0001104506
Period of Report: 2025-06-16

Reporting Person: Lewis William (Director, Chair and CEO)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-06-16	Common Stock	S	442	$98.51	Disposed	308316	Direct
2025-06-16	Common Stock	S	1558	$99.65	Disposed	306758	Direct
2025-06-16	Common Stock	S	2300	$100.70	Disposed	304458	Direct
2025-06-16	Common Stock	S	904	$101.39	Disposed	303554	Direct
2025-06-16	Common Stock	M	129805	$10.85	Acquired	363729	Indirect
2025-06-16	Common Stock	S	7000	$98.50	Disposed	356729	Indirect
2025-06-16	Common Stock	S	32490	$99.51	Disposed	324239	Indirect
2025-06-16	Common Stock	S	48531	$100.54	Disposed	275708	Indirect
2025-06-16	Common Stock	S	41784	$101.23	Disposed	233924	Indirect

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-06-16	Stock Option (right to buy)	$10.85	M	129805	Disposed	2026-05-19	Common Stock (129805)	Indirect

Holdings (Non-Derivative)

Security	Shares	Ownership
Common Stock	50500	Indirect

Footnotes

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on September 12, 2024, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2: This is the weighted average sales price representing 442 shares sold at prices ranging from $98.08 to $98.94 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F3: This is the weighted average sales price representing 1,558 shares sold at prices ranging from $99.17 to $100.16 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F4: This is the weighted average sales price representing 2,300 shares sold at prices ranging from $100.19 to $101.07 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F5: This is the weighted average sales price representing 904 shares sold at prices ranging from $101.20 to $101.58 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F6: This is the weighted average sales price representing 7,000 shares sold at prices ranging from $97.93 to $98.92 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F7: This is the weighted average sales price representing 32,490 shares sold at prices ranging from $98.94 to $99.93 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F8: This is the weighted average sales price representing 48,531 shares sold at prices ranging from $99.94 to $100.93 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F9: This is the weighted average sales price representing 41,784 shares sold at prices ranging from $100.94 to $101.61 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F10: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.