INSMED Inc — Director's Dealing 2025

Jul 23, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: INSMED Inc (INSM)
CIK: 0001104506
Period of Report: 2025-07-21

Reporting Person: Bonstein Sara (Chief Financial Officer)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-07-21	Common Stock	M	3443	$26.46	Acquired	87460	Direct
2025-07-21	Common Stock	M	11455	$28.88	Acquired	98915	Direct
2025-07-21	Common Stock	M	15890	$29.13	Acquired	114805	Direct
2025-07-21	Common Stock	M	17100	$34.03	Acquired	131905	Direct
2025-07-21	Common Stock	S	32090	$102.38	Disposed	99815	Direct
2025-07-21	Common Stock	S	26310	$103.03	Disposed	73505	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-07-21	Stock Option (right to buy)	$26.46	M	3443	Disposed	2031-05-12	Common Stock (3443)	Direct
2025-07-21	Stock Option (right to buy)	$28.88	M	11455	Disposed	2030-02-03	Common Stock (11455)	Direct
2025-07-21	Stock Option (right to buy)	$29.13	M	15890	Disposed	2034-01-04	Common Stock (15890)	Direct
2025-07-21	Stock Option (right to buy)	$34.03	M	17100	Disposed	2031-01-07	Common Stock (17100)	Direct

Footnotes

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on March 5, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2: This is the weighted average sales price representing 32,090 shares sold at prices ranging from $101.77 to $102.76 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F3: This is the weighted average sales price representing 26,310 shares sold at prices ranging from $102.77 to $103.37 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F4: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.

F5: The options become exercisable based on the following vesting schedule: 25% vest on the first anniversary of the grant date and an additional 12.5% vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.