INSMED Inc — Director's Dealing 2025

Aug 6, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: INSMED Inc (INSM)
CIK: 0001104506
Period of Report: 2025-08-04

Reporting Person: Flammer Martina M.D. (Chief Medical Officer)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-08-04	Common Stock	M	8715	$19.74	Acquired	91826	Direct
2025-08-04	Common Stock	S	8715	$109.50	Disposed	83111	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-08-04	Stock Option (right to buy)	$19.74	M	8715	Disposed	2033-01-05	Common Stock (8715)	Direct

Footnotes

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on June 7, 2024, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2: The options become exercisable based on the following vesting schedule: 25% vest on the first anniversary of the grant date and an additional 12.5% vest on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.