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INSMED Inc Director's Dealing 2025

Nov 14, 2025

30150_dirs_2025-11-14_ccc9fa41-fdf1-428e-9a3a-6f2362ff0c0a.zip

Director's Dealing

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SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: INSMED Inc (INSM)
CIK: 0001104506
Period of Report: 2025-11-12

Reporting Person: Schaeffer Orlov S Nicole (Chief People Strategy Officer)

Non-Derivative Transactions

Date Security Code Shares Price A/D Holdings After Ownership
2025-11-12 Common Stock M 30000 $26.46 Acquired 66461 Direct
2025-11-12 Common Stock S 4078 $192.45 Disposed 62383 Direct
2025-11-12 Common Stock S 6575 $193.64 Disposed 55808 Direct
2025-11-12 Common Stock S 19183 $194.44 Disposed 36625 Direct
2025-11-12 Common Stock S 164 $195.88 Disposed 36461 Direct

Derivative Transactions

Date Security Exercise Price Code Shares A/D Expiration Underlying Ownership
2025-11-12 Stock Option (right to buy) $26.46 M 30000 Disposed 2031-05-12 Common Stock (30000) Direct

Footnotes

F1: This is the weighted average sales price representing 4,078 shares sold at prices ranging from $192.00 to $192.95 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F2: This is the weighted average sales price representing 6,575 shares sold at prices ranging from $193.02 to $194.01 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F3: This is the weighted average sales price representing 19,183 shares sold at prices ranging from $194.02 to $194.95 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F4: This is the weighted average sales price representing 164 shares sold at prices ranging from $195.42 to $195.96 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F5: The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.