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INSMED Inc Director's Dealing 2025

Dec 3, 2025

30150_dirs_2025-12-03_eac0ec6a-889b-49ac-adea-05b0b3f2bb16.zip

Director's Dealing

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SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: INSMED Inc (INSM)
CIK: 0001104506
Period of Report: 2025-12-01

Reporting Person: Flammer Martina M.D. (Chief Medical Officer)

Non-Derivative Transactions

Date Security Code Shares Price A/D Holdings After Ownership
2025-12-01 Common Stock M 8895 $25.83 Acquired 92006 Direct
2025-12-01 Common Stock S 1450 $205.98 Disposed 90556 Direct
2025-12-01 Common Stock S 5886 $207.03 Disposed 84670 Direct
2025-12-01 Common Stock S 1559 $207.73 Disposed 83111 Direct

Derivative Transactions

Date Security Exercise Price Code Shares A/D Expiration Underlying Ownership
2025-12-01 Stock Option (right to buy) $25.83 M 8895 Disposed 2034-05-13 Common Stock (8895) Direct

Footnotes

F1: This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on February 27, 2025, in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

F2: This is the weighted average sales price representing 1,450 shares sold at prices ranging from $205.45 to $206.39 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F3: This is the weighted average sales price representing 5,886 shares sold at prices ranging from $206.48 to $207.47 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F4: This is the weighted average sales price representing 1,559 shares sold at prices ranging from $207.49 to $208.17 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

F5: The options become exercisable based on the following vesting schedule: 25% vest on the first day of the first month following the first anniversary of the date of grant (the Initial Vesting Date) and 12.5% vest on each sixth month anniversary date thereafter through the fourth anniversary of the Initial Vesting Date.