INCYTE CORP — Director's Dealing 2025

Nov 7, 2025

SEC Form 4 — Statement of Changes in Beneficial Ownership

Issuer: INCYTE CORP (INCY)
CIK: 0000879169
Period of Report: 2025-11-05

Reporting Person: Stein Steven H (EVP & Chief Medical Officer)

Non-Derivative Transactions

Date	Security	Code	Shares	Price	A/D	Holdings After	Ownership
2025-11-05	Common Stock	M	1194	$83.83	Acquired	104080	Direct
2025-11-05	Common Stock	M	2995	$95.76	Acquired	107075	Direct
2025-11-05	Common Stock	M	1044	$95.76	Acquired	108119	Direct
2025-11-05	Common Stock	S	5233	$102.20	Disposed	102886	Direct

Derivative Transactions

Date	Security	Exercise Price	Code	Shares	A/D	Expiration	Underlying	Ownership
2025-11-05	Non-Qualified Stock Option (right to buy)	$83.83	M	1194	Disposed	2026-07-14	Common Stock (1194)	Direct
2025-11-05	Non-Qualified Stock Option (right to buy)	$95.76	M	2995	Disposed	2026-01-06	Common Stock (2995)	Direct
2025-11-05	Incentive Stock Option (right to buy)	$95.76	M	1044	Disposed	2026-01-06	Common Stock (1044)	Direct

Footnotes

F1: This includes an aggregate of 100,327 shares of common stock issuable pursuant to previously reported restricted stock units and earned performance shares that have not vested.

F2: Beginning July 15, 2016, options become exercisable in 37 installments, with the first 25% vesting after one year and the remainder vesting monthly over three years.

F3: Beginning January 7, 2016, options become exercisable in full on January 7, 2020.