IMUGENE LIMITED — Major Shareholding Notification 2008

Feb 3, 2008

603 page 1/2

Form 603

Corporations Act 2001

Section 671B

Notice of initial substantial holder

To: Imugene Limited ACN 009 179 551

1. Details of substantial holder (1)

Name Dr Warwick Andrew Lamb

ACN/ARSN (if applicable) n/a

The holder became a substantial holder on 31/01/08

2. Details of voting power

The total number of votes attached to all the voting shares in the company or voting interests in the scheme that the substantial holder or an associate (2) had a relevant interest (3) in on the date the substantial holder became a substantial holder are as follows:

C	lass of securities (4)	lass of securities (4)	N	umber of securities	Person's votes (5)	Voting power (6)
	O	rdinary Shares		7,520,002	7,520,002	5.2%

3. Details of relevant interests

The nature of the relevant interest the substantial holder or an associate had in the following voting securities on the date the substantial holder became a substantial holder are as follows:

H	older of relevant interest	Nature of relevant interest (7)	Class and number of securities
H	ELD DIRECTLY	RegisteredHolder	7,245,002Ordinary Shares
VETSPECPTY LTD		RegisteredHolder	275,000 Ordinary Shares

4. Details of present registered holders

The persons registered as holders of the securities referred to in paragraph 3 above are as follows:

Holder of relevant	Registered holder of		Class and number of
interest	securities	Person entitled to be registered as holder (8)	securities
Dr Warwick Andrew	Dr Warwick Andrew
Lamb	Lamb	Dr Warwick Andrew Lamb	7,245,002Ordinary Shares
VETSPECPTY LTD	VETSPECPTY LTD	VETSPECPTY LTD	275,000 Ordinary Shares

603 page 2/2

5. Consideration

The consideration paid for each relevant interest referred to in paragraph 3 above, and acquired in the four months prior to the day that the substantial holder became a substantial holder is as follows:

5. Consideration	5. Consideration
The consideration paid for each relev		ant interest referred to in paragraph 3 abo		ve, and acquired in the four months prior to
that the substantial holder became a s		ubstantial holder is as follows:
Holder ofrelevantinterest	Date of acquisition	Consideration (9)			Classnumbsecur	ander ofities
		Cash	N	on-cash
	23 January2008	$86,100	n/a		615,001 Fullypaid ordinaryshares
	23 January2008	$3,500	n/a		25,000 Fullypaid ordinaryshares
	31January2008	$67,200	n/a		480,000 Fullypaid ordinaryshares

6. Associates

The reasons the persons named in paragraph 3 above are associates of the substantial holder are as follows:

Name and ACN/ARSN (if
applicable)	Nature of association
VETSPECPTY LTD	ControlledBody Corporate

7. Addresses

The addresses of persons named in this form are as follows:

Name	Address
Dr Warwick Andrew Lamb	Level 1,14-20Delhi Road,NORTH RYDE NSW 2113
VetspecPtyLtd	Level 1,14-20Delhi Road,NORTH RYDE NSW 2113

Signature

print Registered holder and name Warwick Lamb capacity Director sign date 4 / 2 / 08 here