IMUGENE LIMITED — Director's Dealing 2024

Nov 19, 2024

Appendix 3Z Final Director's Interest Notice

Rule 3.19A.3

Appendix 3Z

Final Director's Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX becomes ASX's property and may be made public.

Introduced 30/9/2001.

Name of entity	Imugene Limited
ABN	99 009 179 551

We (the entity) give ASX the following information under listing rule 3.19.A.3 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of director	Jens Eckstein
Date of last notice	02 July 2024
Date that director ceased to bedirector	14 November 2024

Part 1 - Director's relevant interests in securities of which the director is the registered holder

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust Note: In the case of a company, interests which come within paragraph (i) of the definition of "notifiable interest of a director" should be disclosed in this part.

Number & class of securities

(1) 600,000 - Employee Share Option Plan - Options (2) 20,988,095 - Ordinary Fully Paid Shares

(3) 750,000 - Restricted Stock Units (RSUs)

Part 2 - Director's relevant interests in securities of which the director is not the registered holder

Note: In the case of a company, interests which come within paragraph (ii) of the definition of "notifiable interest of a director" should be disclosed in this part.

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust

Name of holder & nature ofinterestNote: Provide details of the circumstancesgiving rise to the relevant interest.Nil	Number & class of SecuritiesNil

Part 3 - Director's interests in contracts

Detail of contract	1. Issue of restricted stock units under the Company'sESOP, as approved by shareholders on 14 November2024.

• See chapter 19 for defined terms.

11/03/2002

Appendix 3Z Page 1

Appendix 3Z Final Director's Interest Notice

Nature of interest	1. Shareholders approved on 14 November 2024 thegranting of 2,000,000 restricted stock units vesting inequal parts over four years to Dr Jens Eckstein, or hisnominee, under Imugene’s ESOP, it is intended that theRSUs will be issued within 30 days after the AnnualGeneral Meeting, but in any event no later than 12months after the Annual General Meeting.
Name of registered holder (ifissued securities)	1. Jens Eckstein
No. and class of securities towhich interest relates	1. 2,000,000 Restricted Stock Units (RSUs)

• See chapter 19 for defined terms.

Appendix 3Z Page 2

11/03/2002