IMUGENE LIMITED — Director's Dealing 2023

Oct 3, 2023

Appendix 3Y Change of Director's Interest Notice

Rule 3.19A.2

Appendix 3Y

Change of Director's Interest Notice

Information or documents not available now must be given to ASX as soon as available. Information and documents given to ASX becomes ASX's property and may be made public.

Introduced 30/09/01 Amended 01/01/11

Introduced 30/09/01 Amended 01/01/11
Name of entity	Imugene Limited
ABN	99 009 179 551

We (the entity) give ASX the following information under listing rule 3.19A.2 and as agent for the director for the purposes of section 205G of the Corporations Act.

Name of director	Lesley Russell
Date of last notice	20 December 2022

Part 1 - Change of director's relevant interests in securities

In the case of a trust, this includes interests in the trust made available by the responsible entity of the trust Note: In the case of a company, interests which come within paragraph (i) of the definition of "notifiable interest of a director" should be disclosed in this part.

Direct or indirect interest	(1) Direct
	(2) Direct
	(3) Direct
Nature of indirect interest	N/A
(including registered holder)
Date of change	(1) N/A
	(2) 03 October 2023
	(3) 03 October 2023
No. of securities held prior to change	(1) 600,000 - EMPLOYEE SHARE OPTION PLAN
	(2) 20,000,000 - ORDINARY FULLY PAID SHARES
Class	(1) EMPLOYEE SHARE OPTION PLAN
	(2) ORDINARY FULLY PAID SHARES
	(3) LISTED OPTIONS @ $0.118, expiring 31 August
	2026
Number acquired	(1) NIL
	(2) 238,095 - ORDINARY FULLY PAID SHARES
	(3) 238,095 - LISTED OPTIONS @ $0.118, expiring
	31 August 2026
Number disposed	(1) NIL
	(2) NIL
	(3) NIL

• See chapter 19 for defined terms. 01/01/2011 Appendix 3Y Page 1

Appendix 3Y Change of Director's Interest Notice

	Appendix 3YChange of Director's Interest Notice
Value/Consideration	(1) N/A(2) $0.084 - ORDINARY FULLY PAID SHARES(3) NIL - Free attaching placement options
No. of securities held after change	(1) 600,000 - EMPLOYEE SHARE OPTION PLAN(2) 20,238,095 - ORDINARY FULLY PAID SHARES(3) 238,095 - LISTED OPTIONS @ $0.118, expiring31 August 2026
Nature of change	Participation in Placement announced 18 August2023 and as approved by shareholders at the EGMheld on 28 September 2023.

Part 2 - Change of director's relevant interests in contracts

Note: In the case of a company, interests which come within paragraph (ii) of the definition of "notifiable interest of a director" should be disclosed in this part.

Detail of contract	N/A
Nature of interest	N/A
Name of registered holder(if issued securities)	N/A
Date of change	N/A
No. and class of securitiesto which interest relatedprior to change	N/A
Interest acquired	N/A
Interest disposed	N/A
Value/Consideration	N/A
Interest after change	N/A

Part 3 -[+] Closed period

Part 3 -+Closed period
Were the interests in the securities orcontracts detailed above traded during a+closed period where prior written clearancewas required?	NO
If so, was prior written clearance provided toallow the trade to proceed during this period?	N/A
If prior written clearance was provided, onwhat date was this provided?	N/A

• See chapter 19 for defined terms. 01/01/2011 Appendix 3Y Page 2